Just stumbling around trying to figure out how the world works.
12.03.2026 07:45
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Just stumbling around trying to figure out how the world works.
It is interesting whether this consumer ens***tification will lead to stronger public discontent than people currently believe.
Some people think the Soviet Union broke apart not because they had an operating space station or nuclear weapons - but because consumer goods supply got worse and worse.
A screenshot of a tech magazine describing PS6 delays because of memory shortages
A screenshot of a tech magazine describing hard drive shortages for 2026, 2027, 2028
Very few things seem to lead to public disquiet at the moment.
One wonders whether the below may.
Panem et circensis.
Interesting this is highlighted the same day as the research on antibiotic resistance in E. Coli, which seems to suggest that dormant microbes are not the ones conferring resistance. Working in an incurable cancer, I wonder whether we will see the same here. We still hardly understand proliferation.
'Empirical data and the theories that make sense of them are the twin pillars of scientific progress. When one pillar is raised much higher than the other, they cease to be good pillars.'
www.nature.com/articles/s41...
Provocative! Not all scientists will want to hear this. I agree with many points. In parallel to emphasis on better communication, I hope weβll begin conversations about maintaining integrity.
asteriskmag.com/issues/13/th...
Itβs a matter of time before Tesla automatically generates non-consensual images of people in revealing clothing as you drive past them.
I know the proliferation of references to non-existent papers, powered by genAI, is getting less surprising and shocking but it doesn't make it any less potentially corrosive to the scholarly knowledge environment.
Are 'unexpected' early relapses really unexpected in #myeloma ? Or a sign for need for wider implementation of and access to already diagnostic tests?
Challenging the concept of functional high-risk myeloma through transcriptional and genetic profiling url: ashpublications.org/blood/articl...
I donβt know if anyone else notices or cares, but when I see a presentation in which the speaker uses obviously generated-AI images to illustrate their slides, it makes me immediately less confident in whatever other content theyβre presenting.
Meet the AI workers who tell their friends and family to stay away from AI
Real-world data is a hot topic with medical regulators and payers in oncology. Here is our analysis comparing a change in induction regimens in multiple myeloma in a public healthcare system, using real-world MRD measurement.
www.clinical-lymphoma-myeloma-leukemia.com/article/S215...
Yet again, we can't afford to let LLMs become a source of epistemic grounding for society.
Very nice reflection on risk and personalisation of medicine in context of regulation
www.gov.uk/government/n...
Doesnβt sound ideal.
"We cannot control who sees what, we cannot see what users are doing, and we cannot verify that the software itself is secure," the memo says.
www.reuters.com/business/aer...
"Researchers recruited to work in the UK have to fund a Β£1,035 annual ο»Ώimmigration health surcharge, which must be paid in full in advance, as well as up to Β£1,519 in visa fees. For a family of four, the upfront costs can total almost Β£30,000."
𧬠Some promising novel candidates for therapeutic inhibition included:
β’ BAFF-R and CD39 in HL
β’ CD25 in MM
β’ CD27 in CLL
β’ CD80/86 in DLBCL
β’ CCR2 in FL and MZL
We are excited to announce our latest publication in #BloodCancerJournal of our Two-Sample MR analysis to investigate causal relationships between 446 immune cell traits and 6 B-cell malignancies
π www.nature.com/articles/s41...
#cancer #genetics #Bcell #bloodcancer #drugdiscovery #MR
Funny how this hypothetical talk of "optimizing" never considers traits like kindness, decency, generosity of spirit... It's always "what does my baby need to get ahead?"
Great comment by @sarahoconnorft.ft.com -- I shared some reflection at the start of the year. To me a revaluation of social status is necessary and potentially a reconfiguration of social organisation away from occupational silos.
www.trfetzer.com/generational...
Peto's Paradoxβthat cancer does not increase with body size of mammalsβwas wrong.
A new, comprehensive study of 263 species documents higher cancer prevalence with increasing body mass. Some large animals (e.g. elephants) have some built-in genetic adaptations
www.pnas.org/doi/10.1073/... @pnas.org
A pleasure to do this British Society of Haematology podcast on advanced imaging in myeloma for earlier diagnosis and morbidity prevention with Dr Ceri Bygrave.
open.spotify.com/episode/1JAq...
Meanwhile, some voting districts (Berlin-Mitte, of all !π) did not manage to send out election materials to voters abroad on time. Certainly not an important feature given the high % of votes casted (which is great) but still disappointing re active democratic participation.
The inverse correlation between articles bemoaning the existential plight of the German economy, and its stock market, is a wonder to behold
Amazing historical quote in the Economist: 'In part owing to the East German governmentβs industrial policy in the 1980s, ..., the region (Saxony) has become Europeβs largest maker of microelectronics'
Fantastic DLF podcast on similar topic ('Neuland')
www.economist.com/finance-and-...
Literally just cleaned survival data for a Sunday R analysis...
China wants in on the pedestrian and cyclist crushing game too.
Which are also not covered for visiting students from EU funders (at least NHS fee not covered by @dfg.de ), making it comfy for junior researchers π
If there's something we don't understand I assume transposons are responsible unless proven otherwise