Why do women benefit more? Female singers tend to partner with older, more experienced male singers who can offer career resources & mentorship.
But having multiple romantic partners also correlates with success in the industry. Could narcissism drives creative ambition?

Homogamy=career boost.
Our study explores the complex ties between love, fame, and creativity in music. Singers with singer romantic partners achieve earlier & more sustained success—especially women. www.nature.com/articles/s41...

Scientists investigate 400 biological cold cases A team of EPFL scientists tested the reproducibility of five decades of research on fly immunity. Most of those research results proved to be valid, but the team made one surprising discovery: the non...

A summary and an interview on our extensive reproducibility project in Drosophila immunity. actu.epfl.ch/news/scienti...

An open webinar on our reproducibility project 'WHAT 400 DROSOPHILA PAPERS Teach Us about Doing Better Science' on December 9th 2PM EEST time (1PM Swiss time). Registration below

Diagrams of fruit fly larvae (left) and adult (right) annotated with genes expressed in different tissues, including male- or female-biased gene expressions.

A diagram providing an overview of the regulation of antimicrobial peptide and other host effector peptides by Toll and Imd signalling, alongside diagrams showing the diversity of the peptides.

A summary table illustrating sequence features common to antimicrobial peptides, and a summary table of gene families.

A diagram giving a model for the mechanisms of antimicrobial peptide and host defence peptide actions in killing microbial cells, including precise mechanisms, broader host-pathogen relationships, and non-microbicidal roles of these peptides in protecting the host.

Bizarre that our 2020 #Drosophila #AMP review already feels out of date.

Thanks to #AnnualReviews to cover the many updates in the field and present a much more complete picture of the diversity, mechanisms, topics, of fly immunity re: host defence peptides.

www.annualreviews.org/content/jour...

Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.

Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...

As someone who ended up using non-model systems after doing his PhD with Drosophila, you don't realise just how amazing FlyBase or WormBase are until you try to genetics without them.

Immune–tracheal intercellular signalling coordinates the muscle injury response in Drosophila Effective tissue adaptation to damage requires precise coordination among diverse cell types. In skeletal muscle, injury-responsive cells play a pivotal role in repair, yet the molecular and cellular ...

I read the preprint. It's very beautiful work from Hadi Boukhatmi's group. They test how if at all #Drosophila can repair their #muscles.
www.biorxiv.org/content/10.1...

Brave Genomes The role of environmentally triggered genetic and epigenetic changes in microbial adaptation and evolution is still not broadly appreciated. Brave Gen

Currently reading Brave Genomes by Silvia Bulgherisi — a wonderful book on recent advances in genomics, environmental change, and the influence of microbes. Highly recommend!

shop.elsevier.com/books/brave-...

www.amazon.de/Brave-Genome...

Majority of fruit fly immunity studies can be replicated, huge analysis finds Verification of 50 years of data bolsters immunology research, but identifies “suspicious” papers that don’t hold up

Comment on our @Reproducibility project in @Drosophila immunity. It is a normal that findings—however exciting and important at the time—may later prove to be more complex than initially believed. Re-evaluations is essential to the self-correcting nature of science. www.science.org/content/arti...

the strain on academic publishing could be substantially alleviated if funding agencies stipulated... work they support must be published in non-profit journals.

Specifically on the #metascience side, congrats to @josephlemaitre.bsky.social and @brunolemaitre.bsky.social on this consequential piece. 🎉

By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.

The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field?

That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience

A 🧵 1/n

Congratulations to @fly-eds.bsky.social board member Gábor Juhász @juhg.hu and to Oren Schuldiner @schuldinerorenlab.bsky.social for their election to EMBO membership!
#Drosophila

FlyCROSS 2025–26: Mentor-mentee matching program - the Node Call for Mentors from the Drosophila community. The Fly Board is excited to announce the second cycle of FlyCROSS (2025–2026), following a successful

#FlyCROSS is a mentor-mentee matching program for the fly community. They're looking for mentors from all career paths (academia, industry, policy etc.) who have experience with #Drosophila research and are eager to support the next generation of fly scientists.

Apply to become a mentor by 14 July:

Michael Ashburner FRS was an influential figure in the fields of Drosophila genomics and early sequencing database initiatives such as @ebi.embl.org.

Read about their contributions across genetics and bioinformatics in the new biographical memoir: buff.ly/f01zNat

@geneticscam.bsky.social‬

drosophila melanogaster

Hidden virus harboured by fruit flies may influence experimental accuracy.
buff.ly/TtHCYLQ

Oh man, you guys. This is so important. Drosophila have led to so much in terms of what we understand about how genes work.

Big #Drosophila news!🪰

The AMP mutant lines from Hanson et al. (elifesciences.org/articles/443...) & the many isogenic immunity strains generated by @lmvteixeira.bsky.social & @brunolemaitre.bsky.social's group are now in @vdrc-flies.bsky.social!

Find the 40 DrosDel Immunity Panel strains at ⬇️

We are happy to annouce that we have deposited at @VDRC
(ViennaDrosophila Resource Center) a list of isogenized @Drosophila immunity mutants affecting all major immune modules and effectors. We hope these strains will be useful to the community.
epfl.ch/labs/lemaitr...

Sad news. Benny Shilo, a pioneer in dev bio & Drosophila genetics, has died.

I'll remember the infectious enthusiasm and burning curiosity he brought to every conversation I had with him.

The Drosophila Immunity Handbook cover, showing flies that are either glowing green or not. All flies are infected by a green-expressing bacteria, but only red-eyed flies glow green because those flies are missing immune genes needed for resistance to infection.

Some hashtags:

#immunity #Dros25 #Drosophila #antimicrobialpeptides #NFkB #inflammation #ImmunoSky #Infection #pathogen

And if you want to learn more about these modules and how you could incorporate them in your research, check our our free book: "The Drosophila Immunity Handbook"
bit.ly/3z429p5

Layers of immunity: Deconstructing the Drosophila effector response The host innate immune response relies on the cooperation of multiple defense modules. In insects and other arthropods, which have only innate immune mechanisms, four main immune-specific modules cont...

Excited to finally announce this work which has been in the pipeline for 5 years: Layers of Immunity.

Faustine et al. made a set of immune mutants covering 4 major immune modules in #Drosophila, deleting melanization (ROS), phagocytosis, and both Toll & Imd NF-kB responses. What did we find?

1/n 🧵

4/ Of course, homogamy in science has trade-offs too. Our study examines the costs & benefits of these relationships. Want to see the data? Check out our preprint here: ⬇️
osf.io/preprints/os...

3/ This dynamic challenges traditional gender gaps in academia. More research time + a supportive partner in the same field = a formula for success?

2/ Motherhood penalty? Less severe in homogamous couples. Our study suggests that when both partners are researchers, men tend to share more of the investigative workload, mitigating career slowdowns for women.

1/ Women in homogamous relationships tend to advance further in science. As they climb the academic ladder, the proportion of homogamous women increases. Could collaboration at home & work be a key advantage? 🤔

Does marrying a fellow scientist boost your career?
In academia, homogamous couples—where both partners are scientists—are common, especially among top achievers. But who benefits more? Let’s dive into our latest research!

Recently completed your #PhD using #Drosophila in a European lab? Apply for the European Drosophila Society best thesis prize!
🏆🪰
Deadline: 28 Feb 2025.
Prize = €1000 & keynote presentation at the EDRC in Alicante @edrc2025.bsky.social!
Info here: europeandrosophilasociety.org/eds-best-phd...

Salut Pedro, je te propose d'en discuter par telephone. Peux tu m'envoyer email à mon addresse epfl: bruno.lemaitre@epfl.ch