Sara Valpione 🌻

Terrible

They create chaos and then promise you that they're going to deal with the chaos that they create. But, in fact, the chaos is what they thrive on. JASON STANLEY How Fascism Works

Chaos in the world creates
churn on Wall Street.
Fascists love chaos and churn to death.

I am writing a paper about gendered publication rates & something I am noticing in the existing literature is that men tend to say the causes for less publications by women are either not well understood, non existent or due to family demands. While women say the cause is systemic and structural.

In a study co-led by myself and Prof @tmem-samuel.bsky.social at The Centre for Cancer Biology, Adelaide University, we found breast cancer cells subjected to compression, such as experienced during tumour growth in the restricted mammary duct, are changed in ways that worsen the resulting tumours.

Online now! Cell-free DNA #methylome and #fragmentome analysis for relapse monitoring of #EwingSarcoma

By S. Richardson, M. McCabe, @florentmouliere.bsky.social & colleagues @cancerresearchuk.org @manchester.ac.uk

➡️ doi.org/10.1038/s44321-026-00396-7

This was a quite wonderful talk and it was a privilege to be there
well worth your time

Cancer death rate in Britain down by almost a third since 1980s Huge improvements in prevention, diagnosis and treatment have driven the fall, Cancer Research UK says

Hugely positive new statistics on cancer reported by @andrewgregory.com in today's @theguardian.com.

Research is powering advances in diagnosing, preventing and treating cancer that are changing and saving lives around the world.

Read the Guardian article ⤵️

www.theguardian.com/society/2026...

Only few days left to apply. We are looking for a motivated and enthusiastic scientific officer to work @cruknbc.bsky.social , close collaboration with @christieinstitute.bsky.social @gastric.bsky.social

Photograph shows researchers working in the National Biomarker Centre labs

Our partners in the Cancer Research UK National Biomarker Centre are recruiting a Scientific Officer to their Translational Immunology group

Starting Salary: £25,000 - £30,000 pa (dependent upon experience)
Closing Date: 15th March
Duration: 2 years fixed

apps.cruk.manchester.ac.uk/recruitment/...

Rationally and in silico guided APOBEC3F-directed CBE for enhanced PDAC genetic therapy #PancreaticCancer 🧪 idp.nature.com/authorize?re...

A MUC1-ALIX complex regulates extracellular vesicle cargo loading with activated SRC to enhance pancreatic cancer progression Extracellular vesicles (EVs) are critical mediators of intercellular communication in the tumor microenvironment and play an essential role in tumor g…

A MUC1-ALIX complex regulates extracellular vesicle cargo loading with activated SRC to enhance #PancreaticCancer progression 🧪 www.sciencedirect.com/science/arti...

In vivo modeling of human γδ T cell ontogeny reveals terminal deoxynucleotidyl transferase as a key regulator of type 3 Vδ2 T cell development Human γδ T cells differ greatly from mouse γδ T cells. La et al. report that it is possible to generate bona fide human γδ T cells in a humanized immune system mouse model. Additionally, they show tha...

In vivo modeling of human γδ T cell ontogeny reveals terminal deoxynucleotidyl transferase as a key regulator of type 3 Vδ2 T cell development

#gdTcells @cp-cellreports.bsky.social

Molecular subtypes in pancreatic cancer: from academic promise to clinical reality - Molecular Cancer Pancreatic ductal adenocarcinoma (PDAC) continues to rank among the most lethal malignancies, with five-year survival rates stubbornly below 12%. Over the past decade and a half, transcriptomic analys...

We are thrilled to share our new review article just published in Molecular Cancer Our team explores the journey of molecular subtyping in pancreatic cancer: moving from academic promise to clinical reality. link.springer.com/article/10.1...
#PDAC @ufvmadrid.bsky.social @imas12.bsky.social

We've been blown away with the response to our map of women through science history, with over 125 submissions so far, and 70 landmarks added across the UK. Submit your suggestions now and help us map science history. #WomenInSTEM #InternationalWomensDay royalsociety.org/news-resourc...

It's #InternationalWomensDay, and for the past year we've been commemorating the 80th anniversary of the election of our first women Fellows. Find out more about trailblazing women scientists and help us chart science history with our interactive map: royalsociety.org/news-resourc...

The Invisible Billionaire: Daniel Ludwig Podcast Episode · Founders · March 23, 2025 · Bonus · 50m

Have some extra time this weekend? Check out this Founders Podcast episode on our founder Daniel K. Ludwig:

podcasts.apple.com/us/podcast/t...

#CanSky #OncoSky

#BMJExclusive: Consultants’ and resident doctors’ real terms earnings fell more sharply than the average drop across the public sector between 2011 and 2025, a new analysis shows
@nuffieldtrust.org.uk
https://bit.ly/3NgSFhe

CODA maps of responsive vs. non-responsive regions of PDAC tumors

Deep Learning Enabled 3D Multi-Omic Analysis Reveals Molecular Signatures of Heterogeneous Response to Chemotherapy in Pancreatic Cancer

More here: www.biorxiv.org/content/10.6...

🚨 New paper from our lab just published in Nature🚨

www.nature.com/articles/s41...

Discover how 🌱 tumour formation is shaped by tissue context from the very beginning. Cancer is not driven by genetics alone

✨Fantastic team led by Greta Skrupskelyte, Eduardo Rojo, @hariajith.bsky.social

Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition Immune cells populate the old brain, but whether they can be specifically targeted to improve brain function in older individuals remains unclear. Navarro Negredo et al. dissect how aging impacts brai...

Excited to share our new study using engineered immune proteins to quench inflammation in aged brains!!

Congratulations to Paloma Navarro and the entire team!

Fantastic collaboration with Chris Garcia's lab, Tony Wyss-Coray's lab, and Saul Villeda's lab!

www.cell.com/immunity/ful...

National Oesophago-Gastric Cancer Audit (NOGCA) - National Cancer Audit Collaborating Centre We use some essential cookies to make this website work.

❤️ Need support for OG cancer? Connect with @cancerresearchuk.org, #macmillan and explore other vital resources linked on our site!

Visual representation of "TP53"

𝐓𝐏𝟓𝟑 is the gene that encodes the tumor-suppressor protein p53.

Full definition of this NEJM Illustrated Glossary term: nej.md/4cINZuK

#ScienceSky

Photograph of Alice Sherrard Text says "A very warm welcome to Dr Alice Sherrard New Group Leader Chromatin Regulation in Cancer" Background shows an electron microscope tomograph with gold labelling

We are delighted to announce that Alice Sherrard will be joining the Institute as a Group Leader in October!

Alice is an outstanding researcher with expertise in #chromatin topology & #ElectronMicroscopy, combing these with genetic models in her new research group - Chromatin Regulation in Cancer

Her research will combine cutting-edge light & electron microscopy, genome editing & genomics in embryonic and #cancer models to address fundamental questions in #chromatin biology & her interest in how #TumourMicroenvironment signals impact chromatin regulation open up collaborative opportunities

FEBS Advanced Lecture Course 2026 - Tumour microenvironment: From tumour heterogeneity to therapy resistance 4–8 May 2026 │ Fodele, Greece

One week left to register for the FEBS Advanced Course on Tumour Microenvironment: From Tumour Heterogeneity to Therapy Resistance. which will be held in May 4-8, 2026, in Crete! 🧑‍🔬 🧪 🔬
There is an excellent line up of internationally recognized speakers!

tumourmicroenvironment2026.febsevents.org

Good morning, all! The past week has seen some fantastic papers in #cancermetabolism and #mitochondrialbiology. Check them here: biomed.news/bims-camemi/... Biomed News #keepreading

"Time, which changes people, does not alter the image we have of them."-Marcel Proust

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Do you know anyone keen to study cancers of unmet need and understand how to improve their responses to treatment? We are looking for a curious enthusiastic scientific officer to work at @cruknbc.bsky.social , close ties with @manchester.ac.uk and @christieinstitute.bsky.social

We are #Hiring! Our lab is looking for a LabTech/Lab Manager! Take a look to our research here!
physics-of-life.tu-dresden.de/team/pol-gro...
Drop a line if you are interested to know more details!
#labtech #labtechnician #biology #labtechnicians #labmanager #labwork #Xenopus #zebrafish #devbiol