TTVguideTX

The TTVguideIT trial uses a compound endpoint incl infection, organ rejection & patient- & graft survival. The team around @gregorbond.bsky.social at @meduniwien.ac.at used clinical trial simulations to optimise primary-analysis strategies for such multiple endpoints: www.nature.com/articles/s41...

Torque Teno Virus Loads and Leukocyte Populations in Stable Outpatient Solid Organ Transplant Recipients Dosing immunosuppressive medication after solid organ transplantation remains a challenge, with no established marker of immune function available for routine clinical use. Torque teno virus (TTV), a ...

Associations between #TTV and Leukocyte Populations in Solid Organ Transplant Recipients - Partners in The Netherlands provide evidence to support the theory that TTV replicates in immature granulocytes. www.ijidonline.com/article/S120... #TTVguide

Immune Monitoring Goes Viral 🦠 Torque Teno Virus
for Immunologic Risk Stratification After Kidney Transplantation

⏩️ new review in TI 🔥

doi.org/10.3389/ti.2...
#ttvguide

Statistical analysis plan for TTVguideIT—a multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and Torque Teno virus-guided immuno... Background Non-interventional studies indicate an association between Torque Teno Virus (TTV) load in peripheral blood and immunosuppression related outcomes in kidney transplant recipients. This make...

can viruses 🦠 be superheroes 🦸‍♂️ ?

PhD student Felix Herkner just published the statistical analysis plan
of the TTVguideIT trial 💪👏

Torque Teno virus guided immunosuppression #TTVguide

data cleaning until Q1/26
analysis Q2/26

trialsjournal.biomedcentral.com/articles/10....

happy to speak about TT virus 🦠 @Italien 🇮🇹 micro biology congress

TTV based immune monotoring
#TTVguide

Last week, our team around @gregorbond.bsky.social from @meduniwien.ac.at took part in the "Kinderuni Wien" - Vienna’s Children’s University - to bring science to life for curious kids aged 7 to 12, where the kids learnt that some viruses like TTV can also be superheroes. #TTVguide

🗞️ New paper out: Detection of non-intact Torque Teno viral particles. Partners in Italy have analysed the added value of PMAxx™ treatment to detect non-intact Torque Teno viral particles which may overestimate viremia quantified by digital droplet PCR. #TTV #TTVguide www.mdpi.com/1422-0067/26...

Interesting insights into running clinical studies in EU projects.

Our team around @gregorbond.bsky.social recently participated at #ESOT2025 - here's our most important learnings: 🔸 More & more groups worldwide pick up the idea of TTV-guided immunosuppression. 🔸 First data on the association between TTV load & the development of malignomes is available. #ttvguide

#ESOTCongress 2025 London 🇬🇧 action at the eposters
Torque Teno virus 🦠
for the prediction of Infection post kidney TX
first long term data
#TTVguide

freddi at #ESOTcongress 🇬🇧

depression is a major factor
for reduced HRQOL
post kidney TX

@fredhaupenthal.bsky.social

happy 😊 meeting you
@ #ESOTcongress
this Monday 1.7.
in London 🇬🇧

talks 🗣️ on Torque Teno virus 🦠 guided immunosuppression 💊

09:30 and 11:00 room S1
13:15 room S5, 16:15 room S4

#ttvguide

meet me at #ESOTcongress in London 🇬🇧

🗓️ July 1, 13:00-14:00, ROOM s5

to discuss Torque Teno virus 🦠 based immunologic monotoring

viruses 🦠 can be superheroes 🦸

#ESOT2025 #TTVguide #ESOT

Very happy to see #TTV having the opportunity to be presented and discussed in the realm of #rheumatology
Great work of Daniel Mrak and interdisciplinary collaboration😊
POS0914
@squeezeproject.bsky.social
#EULAR2025

#TTV spreading to #Rheumatology. Currently happening at #EULAR2025. @pstudenic.bsky.social #TTVguide

ttps://www.kinderuni-anmeldung.at/event.php?event_id=5410

Are you based in Vienna & have a 7-12 yr old? 🧒🏻👧🏼 Registration opens today for the Vienna Kids University in July where @gregorbond.bsky.social will give a lecture on how some viruses can be true superheroes. 🦠 Kids will learn about the Torque Teno virus & experience being a student. Join & share! 👩🏻‍🏫

congrets to Katharina Mayer receiving the young investigator award @ #ERA25 👏

how do TX baseline and fup data influence TT virus 🦠 load?
#TTVguide

torque teno virus 🦠 load predicts malignoma post kidney TX 💪

👏 carsten herz at #era25

viruses 🦠 can be 🦸 superheros
TTVbased immune monitoring
#TTVguide

Sebastian Kapps presents
first data on Torque Teno virus 🦠
in long-term kidney TX patients
at #ERA25 #TTVguide

Yesterday our team around @gregorbond.bsky.social came together for our Year 4 meeting at @meduniwien.ac.at to celebrate a major milestone: 🩺 The last patient visit has officially been completed in late May. Now we move to data cleaning & analysis. Follow us for insights into the potential of #TTV .

Sebastian Kapps taking science 🧬 to the public 👨🏽‍🦱👩🏾👨🏼‍🦲👵🏼

can we use a virus 🦠 to quantify the immune system? #ttvguide

Comparison of Torque Teno Virus DNA Load in Plasma and Whole Blood The main challenge of immunosuppressive therapy after solid organ transplantation is creating an immunological balance that prevents organ rejection without promoting opportunistic infections. Torque ...

📢 Partners from @chugrenoblealpes.bsky.social showed that TTV DNA load was slightly higher in whole blood (WB) than in plasma. Overall TTV detection was similar and distribution of TTV DNA loads did not differ. Read the full paper here: www.kireports.org/article/S246... #TTVguide

Self-reported Non-adherence to Immunosuppressive Medication Detected by the BAASIS Predicts Allograft Rejections in Kidney Transplant Recipients AbstractBackground. After kidney transplantation adherence to immunosuppressive medication is crucial for graft survival and its assessment requires valid

📢 First results from the AdTorque trial: a prospective study to define the optimal strategy for the detection of non-adherence towards immunosuppressive drugs after #kidneytransplantation. academic.oup.com/ndt/advance-...

Self-reported Non-adherence to Immunosuppressive Medication Detected by the BAASIS Predicts Allograft Rejections in Kidney Transplant Recipients Presented by Gregor Bond Article DOI:

Watch @fredhaupenthal.bsky.social - #TTVguide investigator from @meduniwien.ac.at presenting first data from the AdTorque trial: self-reported non-adherence by the BAASIS predicts graft rejection oup.cloud.panopto.eu/Panopto/Page...

Our coordinator @gregorbond.bsky.social today, presenting results of TTV-guided monitoring at the @squeezeproject.bsky.social General Assembly meeting, supporting SQUEEZE leader of Functional Drug Monitoring, @pstudenic.bsky.social, with spreading the Torque Teno virus to #Rheumatology. #TTVguide

Graphic introducing Ordensklinikum Linz (OKL) as a TTV GUIDE TX trial center, featuring hospital and project logos on a light blue background with an orange gradient

Photo of the main entrance of Ordensklinikum Linz, a large modern hospital building with signage and a tree in front, accompanied by text describing the hospital's nephrology expertise and transplant services

Portrait of Dr. Daniel Cejka, lead nephrologist at OKL, with a description of his role, team members, and nearly two decades of experience in transplant medicine

Portraits of four team members at OKL involved in kidney transplant research, clinical studies, nephrology, virology, and immunologic research, with text highlighting their specific roles and expertise.

It's time to meet another one of the 13 recruiting centres involved in our #clinicaltrial - for one last time we are in Austria. 🇦🇹 Today, meet the #nephrology and #virology team at Ordensklinikum Linz around Daniel Cejka and learn about their roles and contributions to our common cause. #TTVguide

very important study for clinical trial design!!

Torque Teno Virus for Immunologic Monitoring Gregor Bond TTV Webinar YouTube video by Eurofins Viracor

Our scientific coordinator, @gregorbond.bsky.social recently gave a talk on #TTV for immunologic monitoring for @eurofinsviracor.bsky.social. Here's the recording: youtu.be/iGmCIdbXZCY #TTVguide

big news on torque teno virus 🦠 guided immunosuppression

this summer in London 🏴󠁧󠁢󠁥󠁮󠁧󠁿 at the EU Transplant Congress

#TTVguide #ESOTcongress