New preprint out!
In this study, we introduce NanoFLex, a strategy that combines #HaloTag variants with #nanobodies -based immunolabeling to enable rapid, OneStep-IF #lifetime #multiplexing. Possible due to SmartSecondaries fused to #HaloTag from @nanotag.bsky.social: www.biorxiv.org/content/10.6...
#PostdocRecruiting:
My group at the University of Texas at Austin is recruiting a Postdoc in virology and structural biology. Please see more details here:
utaustin.wd1.myworkdayjobs.com/UTstaff/job/...
Informal inquiries are encouraged, and see more lab info here: zunlongke-lab.org
Borrowing virus exits machinery to distillate transmembrane proteins for cryo-EM! Congrats Zunlong and the team!
Great achievement! Congratulations!
My choice this week in @science.org
@florentin-lab.bsky.social
doi.org/10.1083/jcb....
#membrane seminars are back this week wirh Manu @deriverylab.bsky.social and Andela Šarić! Join us on Thursday at 5 pm CET spread the word!
Next preprint"cryo-ET reveals molecular details of tiny legs in green algae"
📢 Registration for the 28th Annual Meeting of the Club Exocytose-Endocytose is open until April 15 !
👉 Register here: exoendo.org/en/evenement...
Please share widely!
@gdrimabio.bsky.social @biologists.bsky.social @sbcf.bsky.social @embo.org @febsletters.bsky.social @sneuroendo.bsky.social
Unlike XRD, cryoEM always gets you a density map. This is simultaneously is a blessing and a curse of the method 😂
Join us next Tuesday for the next @dgz.bsky.social workshop on #trafficking and EVs! Spread the word please!
Beautiful. Haven't seen such a remarkable double-row polysome in the wild, outside the cell-free formed ones.
Nice preprint! We still don’t know how insulin-responsive GLUT4 storage vesicles (GSVs) are made. @steveroyle.bsky.social shows a subset of intracellular nanovesicles sort and retain GLUT4, supplying components that build these unique vesicles.
www.biorxiv.org/content/10.6...
Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳
mrc.tal.net/vx/mobile-0/...
Open Postdoc position in our lab!
#actin #Huntingtin #cryoET #cellbio
If you enjoy working at the interface of cell biology, structural biology, and quantitative imaging, this could be an excellent fit.
ista.ac.at/en/job/postd...
Please share and feel free to reach out if there are questions!
Beautiful work! Congratulations!
There was so much to unpack with this data, we teamed up with the marvellous @margotriggi.bsky.social to help explain what we think is going on. (Please also check out our model of central apparatus assembly here: www.biorxiv.org/content/10.6...)
Its not cryoEM, but still happy for the shout out @cryoempapers.bsky.social 😆
Excited to share this detailed biophysical study of #PhaseSeparation in the Pyrenoid, an algal microcompartment that fixes a third of the Earth's #CO2 🌏. We combine methods across scales, in vitro 🧪 and in vivo 🦠
Thanks for the very fun collaboration! 🤗
#PlantScience 🌾 #TeamTomo 🔬 #LivingPhysics 🧬🧶
Do you want to know more about how Retromer regulates Rab7 activity in yeast? Of course you do. Check out the new collaboration with Andreas Mayer with work led by Catarina Alves and Kevin Chen.
Reminder with <2 weeks to deadline:
Our new movie is online, highlighting the assembly, secretion and mechanism of action of bacterial Tc toxins. We hope you enjoy it and use it for teaching purposes or just for fun. Nature is fascinating!
www.youtube.com/watch?v=UfEf...
Check out the Highlight Issue of Biological Chemistry on the new avenues in organelle biology! I was very honoured to assemble it together with Emma Fenech. We devote it to our mentor Maya Schuldiner on the occasion of her anniversary. Enjoy! www.degruyterbrill.com/journal/key/...
What a teaser. Any hints on where the improvement will come from?
Congrats!
#membrane seminars are back this THURSDAY for a super session with @dr-downes.bsky.social from the @giuliazanetti.bsky.social lab and Xin Zhou from the Ikonen lab! @felixmendu.bsky.social @ishier.bsky.social
Junior professor position at the University of Kaiserslautern! Our Department of Biology is seeking a colleague working with microalgae. This is a wonderful place to do wonderful science with great people! Please, repost :)
Further details:
jobs.rptu.de/jobposting/1...
Our lab @mrclmb.bsky.social in Cambridge is seeking a passionate PhD student to explore transcription-coupled splicing! Join our team for an exciting project to understand human gene regulation 🧬 Feel free to get in touch directly #PhD #cryoEM #biochemistry
www2.mrc-lmb.cam.ac.uk/students/int...
🚨Attention prospective PhD students🚨
Are you interested in molecular mechanisms, RNA viruses, structural biology or biophysics? 🧬🦠🧪
We have THREE fully-funded PhD projects available for October 2026 entry:
www.findaphd.com/phds/?Keywor...
Please share/repost, and get in touch if you're interested
Happy to see our recent Asgard chromatin structures shown in a new light! 🤩👩🏻🎨 - thanks to a beautiful design by @leonoramartinez.bsky.social
The position is split between Göttingen and Rehovot; you’ll lead the project end-to-end with access to state-of-the-art EM and imaging facilities in both places.
