Rituximab 💉and HBV🦠 Prophylaxis
Active HBV --> Avoid ritux ❎
HBV carrier state --> prophylaxis for 18 months ✅
Prior HBV infection --> Moniter every 3 months 🧐
.
source - AJKD core curriculum
www.ajkd.org/article/S027...
#Nephsky
#Medsky
interesting mechanism of action of HCQ in Sjogren's syndrome
- source - uptodate
#nephsky
#Medsky
2013 paper Emphasizing no role for urine for eosinophils in diagnosing acute interstitial nephritis 🔬
PPV - only 15% 😔
Sensitivity - only 30% 😑
journals.lww.com/cjasn/fullte...
#nephsky
#medsky
Cant be more beautiful than this ❤️
#nephsky
#Medsky
www.ajkd.org/article/S027...
Interesting that sick day protocol with tolvaptan in ADPKD includes not only conditions causing volume depletion but also situations with limited water access like long travel in car, air travel etc 😯
@kdigo.org ADPKD guidelines
#nephsky
#Medsky
Screenshot from 2025 DNB prospectus
DNB released prospectus for nephrology exam
But I'm not understanding this condition 😐🤷🏻
#nephsky
#Medsky
Kidneys are way smarter than we think ❤️
From Guyton physiology
ureter renal reflex !
When ureter is blocked (eg stone) afferent from ureter goes to afferent arteriole to reduce urine formation in the blocked system !
#Nephsky
#medsky
Fast forward to 1939
cortisol was named "compound F" when discovered, and hydrocortisone as "compound E" - hence the name THF and THE !!!
Syndrome of apparent mineralocorticoid excess
increased urine THF - tetrahydrocortisol and THE - tetrahydrocortisone
But there is no F in cortisol - why it is called THF
#Nephsky
#Medsky
2/2
"If you are in the placebo group [of a clinical trial], then
you are not receiving any hope of disease control or
remission....That is terrifying"
Again, I am going to put myself through this [clinical trial]
in hopes of receiving the drug that could increase my kidney function by 10%.”
The Importance of Hope in Patients with CKD❤️
From AJKD in a few words
A few inspiring patient quotes from
www.ajkd.org/action/showP...
"...every month you go for your blood test and you kind of
hope and pray that the results are going to be good."
#Nephsky
#Medsky
1/2
Ofcourse 😂😀
Superficially, it might be said that the function of the kidneys is to make urine, but in a more considered view, one can say that the kidneys make the stuff of philosophy itself. ❤️❤️
#fishtophilosopher
#nephsky
Nephrology - is not for normal doctors but for exceptionally skilled physicians 😎
#nephsky
from
www.thelancet.com/journals/lan....
