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Stefanie Kühn

@steffi-k

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Latest posts by Stefanie Kühn @steffi-k

Fast and Luminous: Clip-tag2. As fast as Halo and SNAP-tag2 with some benefits of redesigned substrate, PF instead of BC is from now on CLIP team. We look forward seeing cool applications in multiplexing, CID, sensors, and maybe some new surprising ones!

08.03.2026 10:55 👍 8 🔁 1 💬 0 📌 0

A Cinderella story: raising CLIP-tag from the ashes to shine in fluorescence labeling.
www.biorxiv.org/content/10.6...

08.03.2026 09:28 👍 31 🔁 15 💬 0 📌 1
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Fast, Bright and Reversible Rhodamine Tags for Live-Cell Imaging We present Rho-tag and SiR-tag, engineered protein tags derived from bacterial multidrug-resistance proteins that bind unsubstituted (silicon-) rhodamines with nanomolar affinity, enabling fast, rever...

Teaching an old bacterial protein new tricks: Fast, bright and reversible rhodamine tags for live-cell imaging:

www.biorxiv.org/content/10.1...

Congratulations to Julian Kompa and the entire team.

09.07.2025 19:58 👍 51 🔁 23 💬 0 📌 1
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Molecular recording of cellular protein kinase activity with chemical labeling - Nature Chemical Biology Molecular recorders based on kinase activity-dependent protein labeling track specific kinase activities to understand their link to cellular phenotypes in heterogeneous cell populations and in vivo.

Molecular recording of cellular protein kinase activity with chemical labeling:

www.nature.com/articles/s41...

Congratulations to De-en Sun and the entire team.

10.07.2025 17:46 👍 22 🔁 11 💬 0 📌 0

🚨 Paper alert: SNAP-tag2 for faster and brighter protein labeling

I am more than happy to see the core results of my PhD finally published in Nature Chem.Bio. 🎉

Big thanks to everyone who contributed to this work and supported it along the way. 😊

And I hope you'll have fun using SNAP-Tag2 now!🔬

03.07.2025 20:15 👍 6 🔁 1 💬 0 📌 0

Please check out our new high-affinity split-HaloTag for live-cell protein labeling www.biorxiv.org/content/10.1...
Congratulations to Yin-Hsi Lin!

16.06.2025 14:24 👍 37 🔁 18 💬 0 📌 0