Developed in direct response to NC3Rs recommendations, new guidance from the World Health Organisation (@who.int) encourages manufacturers and regulators to replace or remove animal-based quality control methods for vaccines and biologics: nc3rs.org.uk/news/new-who...
The review is spot on, the play is excellent, huge congratulations! Sorry I missed you though!
Got my tickets ๐
The EDA logo next to an experimental design diagram. Text below reads: 'Train the trainer'.
Looking for support to teach experimental design? Join our online workshop with @ukrepro.bsky.social on using the Experimental Design Assistant (EDA) to plan rigorous, reproducible animal studies.
๐
13 November, 10.00 โ 16.00 (GMT)
โ Registration closes: 17 September
๐ nc3rs.org.uk/events/ukrn-...
screenshot of speaker and slide showing failure rates of antibodies
At the @nc3rs.bsky.social Prize ceremony and hearing about YCharOS- stonkingly high percentage of commercial antibodies don't work in applications for which they are recommended ๐ฌ
Pocket-sized ARRIVE 2.0 guidelines.
ARRIVE 2.0 turns five! Since we launched our updated guidelines in July 2020, we have developed a suite of resources to embed transparency and reproducibility throughout the research lifecycle, from planning to peer review: arriveguidelines.org/resources
But p-piratage sounds amazing, go with it! ๐
Aie bonne chance! Cet article contient plusieurs des termes courants www.polytechnique-insights.com/dossiers/soc...
View from an airplane window showing part of the wing and small islands
So glad to be back in Hong Kong! ๐ญ๐ฐ
Now let the marathon week begin, we will be presenting seven @nc3rs.bsky.social talks and workshops over four days. Iโm especially looking forward to the HKLASS symposium hklass.org
๐ข Free seminar by @bihatcharite.bsky.social on ๐๐ฎ๐ง๐ ๐๐!
Dr. Nikki Osborne ( @rrr-research.bsky.social) & Dr. โช @nathalie-pds.bsky.social (โช@nc3rs.bsky.social) will share tools for responsible & robust preclinical research.
๐ bihealth.org/de/translati...
#OpenScience #NC3Rs #PreclinicalResearch
Amazing account of ChatGPT's sycophancy and confabulation on steroids.
amandaguinzburg.substack.com/p/diabolus-e...
Great to see this publication optimising a hydrogel-based model of cartilage. This approach has the potential to become a scalable platform to investigate biomechanical responses and replace mice in studies of musculoskeletal disease progression and ageing.
Learn more:
nc3rs.org.uk/our-portfoli...
URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. ๐คฌ๐คฏ
Any lab using @flybase.bsky.social please donate using the link in post below.
This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
Icons representing new approach methodologies and chemical and drug safety testing, in a speech bubble.
SURVEY: New approach methodologies in safety assessment
Are you involved in the development and application of replacement technologies for toxicity testing or submission and assessment of data for regulatory decision making? Help shape our plans for the coming years: nc3rs.org.uk/our-portfoli...
๐ฌ Transparent animal research is ethical, reproducible, and credible.
Want to improve your lab's practices?
Follow this ๐งต on the 10 essentials from the ๐๐๐๐๐๐ ๐๐ฎ๐ข๐๐๐ฅ๐ข๐ง๐๐ฌ
#AnimalResearch #Transparency #ARRIVEguidelines #aRukon
This is a really good explainer about sex, gender and biology. It gives a clear account of the complexity and richness of differences.
๐ก If you are an educator, science communicator or researcher involved in public engagement, this card game from @comeflywithjo.bsky.social can help you talk about how scientists choose the right biological model for their experiments and options to replace animal use.
"Estimating the replicability of Brazilian biomedical science"
For 97 replications of 47 original experiments, 94% of replications were smaller effects than originals, and success rates ranged from 13% to 45% depending on the criterion.
Incredible effort!
Paper: www.biorxiv.org/content/10.1...
NEW | Analysing a story about an academic and smartphone bansโฆ
THE ANATOMY OF A SMEAR
Comparing two news stories about an academic's view on school smartphone bans reveals just how easy it is to twist the narrative.
brokenbottleboy.substack.com/p/4-the-anat...
A quote from Professor Maurice Whelan, Head of EURL ECVAM: โOur longstanding collaboration with the NC3Rs is very important to us and weโve always been great admirers of CRACK IT. The challenge-led format really fosters solution-driven 3Rs innovation and ensures very tight collaboration between developers and end-users. Weโre delighted now to have the opportunity to get involved, to support where we can and to learn from the experience.โ
The EU Reference Laboratory for Alternatives to Animal Testing (EURL ECVAM) have joined two of our CRACK IT projects as Challenge Partners, bringing their experience in validating new approach methodologies to help bridge the gap between innovation and market adoption: nc3rs.org.uk/news/eurl-ec...
Icons representing new approach methodologies to replace animal use for assessing chemical or drug toxicity - a lab flask, a molecule structure on a computer screen and an environmental scene.
Register for our NAMs Network symposium to connect with developers and end-users of new approach methodologies and join the discussion about reducing the reliance on animals for toxicity testing.
๐๏ธ Thursday 1 May, 9.30 โ 17.00
๐ London, UK
๐ nc3rs.org.uk/events/nc3rs...
Invitation to the Meta-Science Summer School and logos of affiliated and organizing institutions: Berlin Institute of Health (BIH), the German Reproducibility Network (GRN), the META REP Priority Program, iRise and the University of Coimbra EXCELScIOR project ERA chair.
๐ฌโจ Interested in research transparency & reproducibility? Join the Meta-Science Summer School: design & launch a meta-research study!
โก๏ธ Co-org. @germanrepro.bsky.social
๐
Date: 15-20 June 2025; apply by March 21!
๐ www.bihealth.org/en/notices/m...
#OpenScience #Reproducibility #MetaResearch (lmf)
There have been people less than helpful in my journey here. I wanted to acknowledge those too, bc I know I am not unique in this experience. No thank you to the physics study assoc that made me sing songs about how women couldn't study physics without sleeping with the professor, the day I stepped into university life. No thank you to the 5th year physics student that decided to assign me a stripper name within the first minute of meeting me in the physics coffee corner in my first year. No thank you to the technician that was responsible for onboarding me on the use of the cluster in my third year who raised his eyebrows and asked me if that meant I was some sort of computer girl. No thank you to the senior researcher that sent me utterly inappropriate texts after a conference, then proceeded to apologise months later by telling me they had not been meant for me anyway so no hard feelings remain hopefully And no thank you to him for attending every conference I've been to since. No thank you to the people who told me that it was surprising that I was doing a PhD since I was a girl. No thank you to the man who mistook me for a coffee lady at a conference, and after having to correct him two times that I did not work there, responded with you should consider it. No thank you to the researcher that asked me what I was wearing underneath my outfit during a conference. No thank you to the physicist who declared to a room full of other physicists that biologists don't know how to design an experiment. No thank you to the people who have called me scary instead of strong and intimidating instead of intelligent. And finally, no thank you to the exec board of the TU Delft, whose knee-jerk reaction to being held up a mirror about the social safety at the university, was to sue the party holding up the mirror instead of looking at the problems they highlighted. ... You have made me feel like I do not belong in science & I cannot forgive you for that.
A friend included this anti-acknowledgement section on her PhD thesis. She also added the proposition: โSystematic bullying and undermining of girls and women in STEM starts early on and is the reason why they do not stay in science and related fields.โ
Absurd we still need to go through this
๐งช๐ฉโ๐ฌ
dnschecker.org#A/pubmed.ncb... They're removing it from DNS.
You can currently get to it using the IP address 34.107.134.59 (add it to your hosts file or local DNS server), but like with USAID it's probably just a matter of time until it's gone unless they're forced to restore it.
#pubmed
Pubmed is currently still working for me but not sure how long this will hold. Here is @hildabast.bsky.social โs blog post on what to do if Pubmed becomes unreliable absolutelymaybe.plos.org/2025/02/14/w...
Sunrise over the Tyrol alps It will be alright in the end. And if it's not alright, it is not yet the end. #AcademicSky #ClimateSky #Altmetrics
THREAD
Things that didn't make the news that will likely change our lives for the better
The news is not an accurate reflection of the world.
Good news doesn't get reported as much.
Here are the wonderful things researchers have achieved recently.
1/24
The Togeth3R Consortium logo and an icon of an immune cell. Text reads: The Togeth3R Consortium presents non-animal approaches in infection and immunity webinar, Wednesday 26 February.
If your research focuses on infection or immunity join us in two weeks to stay updated on non-animal approaches in the field, including organoids, human cell-based assays and virtual twins.
๐ฆ Register for the webinar: nc3rs.org.uk/events/non-a...
๐
Wednesday 26 February, 13.00 (GMT)/14.00 (CET)
#LoveMethods25 is coming in two weeks.
๐ฌ Love Methods Week 2025 โ Putting Methods like #RRID in the Spotlight! โค๏ธ
โ
Document your methods with precision โ to maximize reusability, transparency, and visibility
โก Choose from 17 different session and register here: www.bihealth.org/de/aktuell/l...
An open letter to the President of the @royalsociety.org โ time to stand up for your values. occamstypewriter.org/scurry/2025/...
To help you connect with us and each other, we've created a Starter Pack of UK Reproducibility Network people and affiliated organisation on BlueSky:
#AcademicSky #OpenResearch #Research
