Rahul K's Avatar

Rahul K

@theresearch

I run, ski, and engineer cells and materials; asking how nutrient sensing & signaling work: bit.ly/RK-GoogleScholar ๐Ÿ‡ช๐Ÿ‡ช: TalTech| Ex: Tartu รœlikool; ๐Ÿ‡ธ๐Ÿ‡ช: Karolinska Institutet, Chalmers; ๐Ÿ‡ฏ๐Ÿ‡ต: Kyutech; ๐Ÿ‡ฎ๐Ÿ‡ณ: IITD

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28.11.2023
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Latest posts by Rahul K @theresearch

Really exciting to hear Dan Gottschling (formerly of @fredhutch.org now @ Calico) on novel insights into cellular aging pathways in yeast using clever cellular, genetic and technological tools. Some recent papers: doi.org/10.1083/jcb.... ; doi.org/10.64898/202... ; review: doi.org/10.1146/annu...

10.03.2026 19:47 ๐Ÿ‘ 13 ๐Ÿ” 3 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Professor of Integrated Immunology

To all immunologists looking for amazing opportunities at a fantastic school/university. Please check the opening for a professorship in Integrated Immunology below ๐Ÿ‘‡. Please don`t forget: ETH is a fantastic place to work and live!!
ethz.ch/en/the-eth-z...

10.03.2026 18:48 ๐Ÿ‘ 0 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Framework for microbiome-inspired functional synthetic communities

Framework for microbiome-inspired functional synthetic communities

One of the biggest challenges in microbial biotechnology? Unlocking the potential of non-model microbes and synthetic communities! Glad to share our review @sonjablasche.bsky.social @simonemozzachiodi.bsky.social @kiranrpatil.bsky.social @cambridgebiosci.bsky.social๐Ÿงต(1/7) doi.org/10.1016/j.co...

10.03.2026 15:06 ๐Ÿ‘ 23 ๐Ÿ” 10 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1
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Johan Elf, Professor at Uppsala University, former EMBO Young Investigator and EMBO Member since 2022, speaks with us about his work and the importance of EMBO to his #career. ๐Ÿงช

Continue reading:
https://www.embo.org/the-embo-communities/embo-communities-by-country/focus-on-sweden/

10.03.2026 13:35 ๐Ÿ‘ 5 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Gene regulatory networks: from correlative models to causal explanations - Nature Reviews Genetics In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without compromising explanatory power.

"GRNs, which should provide mechanistic explanations, are increasingly reduced to statistical correlations โ€” โ€˜hairballsโ€™ that fail to capture molecular causation"

By Maizels and @jamesbriscoe.bsky.social

www.nature.com/articles/s41...

10.03.2026 13:22 ๐Ÿ‘ 12 ๐Ÿ” 10 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0
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Lab logo facelift to better reflect our research focus. More about our lab here: bibellab.lmu.build

10.03.2026 11:55 ๐Ÿ‘ 9 ๐Ÿ” 4 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

SEED2026 abstract deadline extended to 3/15!! there's still time to submit an abstract for a talk or poster! #SEED2026 #synbio

10.03.2026 13:09 ๐Ÿ‘ 0 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Beyond Belief The remarkable story of the global movement championing the idea that evidence, not opinions, should guide our decisions

๐Ÿ“ข My book, Beyond Belief: How Evidence Shows What Really Works, is out 28th April. ๐Ÿšจ๐Ÿšจ

โ€œan incredibly engaging popular science book that illustrates why we should care about good quality evidence.โ€

Preorders *really* help! ๐Ÿ™
@princetonupress.bsky.social
press.princeton.edu/books/hardco...

10.03.2026 13:11 ๐Ÿ‘ 12 ๐Ÿ” 7 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Resolution on Scientific Publishing and MIT Libraries.pdf

MIT graduate student council "calls for adoption of preprints...to
accelerate communication of scientific discoveries, and restore healthy incentives" drive.google.com/file/d/1KLbj...

10.03.2026 13:14 ๐Ÿ‘ 12 ๐Ÿ” 6 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Open Science round-up: Making preprints count - International Science Council In this issue, we feature an editorial by the International Network for Advancing Science and Policy (INASP) on how funders and policy-makers can support a faster, more equitable publishing system by ...

"Funders serious about timely, open, and equitable access to research must explicitly recognize preprint sharing as a route to Open Access compliance"

I know I'm a broken record on this but it seems so blindingly obvious... #PlanU journals.plos.org/plosbiology/...

council.science/blog/open-sc...

10.03.2026 13:17 ๐Ÿ‘ 15 ๐Ÿ” 12 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2
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Just discovered the wonderful covers of 'Genes to Cells', the journal of the Molecular Biology Society of Japan @mbsj-official.bsky.social โ€“ absolutely beautiful!

here some examples inspired by mitosis, CRISPR, the DNA helix, and plant pigments

04.02.2026 19:01 ๐Ÿ‘ 114 ๐Ÿ” 37 ๐Ÿ’ฌ 6 ๐Ÿ“Œ 5
A figure showing a 'Simplot' which plots the similarity of a genome to other genomes across a graph, with similarity on the Y-axis and the genome position on the x-axis. Many coloured lines show the sequences being compared - those closest to the top (similarity of 1) are the closest matches in different parts of the genome.

A figure showing a 'Simplot' which plots the similarity of a genome to other genomes across a graph, with similarity on the Y-axis and the genome position on the x-axis. Many coloured lines show the sequences being compared - those closest to the top (similarity of 1) are the closest matches in different parts of the genome.

1/5

Introducing SimPlot-CL! ๐Ÿงฌ
Recombination plays an important role in viral evolution. Similarity plots are a great way to visualize recombination patterns, but generating them across many genomes can be cumbersome

(Work with my student, Keno Strotjohann!)
๐Ÿ“‚ github.com/hodcroftlab/simplot-cl

10.03.2026 09:21 ๐Ÿ‘ 22 ๐Ÿ” 12 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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The Intersecting Physical Mechanisms That Regulate Cell Viability in 3D Synthetic Hydrogels This study coordinates multiple cell-biomaterial interfaces to evaluate the overlapping physical signals of stiffness, solute transport, and cell confinement presented when cells are encapsulated in ...

Latest issue of curated #engineeredlivingmaterials feed:
biomed.news/bims-enlima/...

via @biomednews.bsky.social | #livingmaterials #ELMs

includes research on: tough hydrogels enabled by transient entanglements, physical mechanisms that regulate cell viability in 3D synthetic hydrogels, & more ๐Ÿงช

09.03.2026 09:56 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Ultrafast-relaxing and photopolymerizable PEG hydrogels enable viscoelasticity-mediated cell remodeling in synthetic matrices Photopolymerizable BELA hydrogels combine dynamic boronate ester and elastic dithiolane-ene crosslinks to achieve ultrafast stress relaxation and tunable viscoelasticity. By adjusting formulation and ...

Latest issue of curated #engineeredlivingmaterials feed:
biomed.news/bims-enlima/...

via @biomednews.bsky.social | #livingmaterials #ELMs

includes research on: cell remodeling in synthetic matrices, designing self-healing, printable, and tough conductive hydrogels, matter and microbes & more ๐Ÿงช

09.03.2026 09:51 ๐Ÿ‘ 1 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Mechanisms of gene regulation by SRCAP and H2A.Z - Nature Communications SRCAP depletion causes rapid replacement of H2A.Z by H2A, leading to upregulation of lineage-specific transcription factors. SRCAP also prevents pioneer transcription factor binding by steric hindranc...

How do the H2A.Z histone variant and its dedicated chromatin remodeller SRCAP regulate gene expression ?
Beautiful work from @armelletollenaere.bsky.social now published @ www.nature.com/articles/s41...

09.03.2026 16:13 ๐Ÿ‘ 26 ๐Ÿ” 14 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0
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Why โ€˜quantum proteinsโ€™ could be the next big thing in biology Fluorescent proteins with a quantum upgrade could offer unprecedented views inside cells.

โ€œIn the past, it might have seemed like, โ€˜ah, thatโ€™s likely never going to workโ€™,โ€ says physicist Ania Jayich. โ€œThatโ€™s not true any more.โ€

go.nature.com/3NdJMF1

09.03.2026 18:45 ๐Ÿ‘ 25 ๐Ÿ” 9 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Two decades of induced pluripotent stem cell research: From discovery to diverse applications Since the discovery of induced pluripotent stem cells (iPSCs) 20 years ago, iPSC technology has transformed stem cell research and regenerative medicine. This perspective reviews key advances in reprogramming mechanisms and highlights the growing clinical, translational, and societal applications of iPSCs.

Two decades of induced pluripotent stem cell research: From discovery to diverse applications

09.03.2026 19:09 ๐Ÿ‘ 11 ๐Ÿ” 8 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Are you passionate about interdisciplinary research and eager to contribute to groundbreaking discoveries in the areas of #biochemistry, #structuralbiology, #biophysics, #cellbiology, #chemicalbiology and #syntheticbiology? Apply NOW for a #fullyfunded #PhDpositions @IMPRS-LM.
Deadline: April 6

05.03.2026 09:59 ๐Ÿ‘ 2 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Programmable Genomics Laboratory | Home

The Programmable Genomics Lab at @umasschan.bsky.social
just officially launched our site!

We have a "simple" goal: to develop synthetic regulatory elements that target every cell type in every tissue, and control payload dosage/duration

Check it out!

programmable-genomics.github.io

09.03.2026 17:46 ๐Ÿ‘ 10 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
The Francis Crick Institute hiring Postdoctoral Fellow Cancer Biologist โ€“ V Li lab in London Area, United Kingdom | LinkedIn Posted 4:23:16 PM. Details of the role:Reports to: Vivian Li, Senior Group LeaderWorking pattern: This is a full-time,โ€ฆSee this and similar jobs on LinkedIn.

๐Ÿ“ข We are seeking highly talented and motivated cancer biologist to join our lab at @crick.ac.uk to investigate cell state rewiring in colorectal cancer and the implications in drug resistance. This project is funded by @cancergrand.bsky.social the REWIRE-CAN team.
www.linkedin.com/jobs/view/43...

09.03.2026 17:49 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Flyer for symposium: https://ctrlepiedit.sciencesconf.org/

Flyer for symposium: https://ctrlepiedit.sciencesconf.org/

Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

09.03.2026 13:15 ๐Ÿ‘ 77 ๐Ÿ” 55 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 5
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How does the cell tune p97/Cdc48 activity for different substrates?
Study suggests different adaptor combinations function as molecular accelerators of protein clearance.

www.science.org/doi/10.1126/...

09.03.2026 00:51 ๐Ÿ‘ 10 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
LMU Klinikum Mรผnchen hiring Staff Scientist / Postdoc โ€“ Tissue Clearing & 3D Image Analysis in Greater Munich Metropolitan Area | LinkedIn Posted 8:17:54 AM. About us ๐Ÿง ๐Ÿ”ฌThe Institute for Stroke and Dementia Research (ISD) at LMU Klinikum is a highlyโ€ฆSee this and similar jobs on LinkedIn.

Hiring in Munich: Staff Scientist / Postdoc in Tissue Clearing and 3D Image Analysis. Weโ€™re looking for someone with strong hands-on expertise in tissue clearing, light-sheet microscopy, and quantitative 3D image analysis. Shares and recommendations are very welcome.
www.linkedin.com/jobs/view/43...

09.03.2026 12:16 ๐Ÿ‘ 8 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 4

๐ŸšจOnly 1 week left to apply๐Ÿšจ 3-year Postdoc Position on Spatial Biology & Bioinformatics in my lab at Oxford๐Ÿ‘‡:

09.03.2026 07:23 ๐Ÿ‘ 4 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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the most annoying shift in my academic career

09.03.2026 10:22 ๐Ÿ‘ 207 ๐Ÿ” 34 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 6
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Research cohorts The EPSRC University Doctoral Landscape Award funded PhD projects in the Faculty of Medicine are listed below under each mini-cohort. PhD projects wi...

๐Ÿšจ Four fully funded PhD studentships ๐Ÿšจ @imperialmed.bsky.social , @imperialcollegeldn.bsky.social

We will be recruiting soon for four PhD positions to build a mini-cohort centered using synthetic cells for medical applications

Check out projects here: www.imperial.ac.uk/medicine/stu...

07.03.2026 08:48 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

New preprint on the limits of detecting higher-order interactions in microbial communities.
www.biorxiv.org/content/10.6...
We find that the dominance of additive and pairwise interactions on community function may not reflect biological simplicity, but fundamental limits of statistical detection.

09.03.2026 09:31 ๐Ÿ‘ 93 ๐Ÿ” 51 ๐Ÿ’ฌ 4 ๐Ÿ“Œ 2
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The Intersecting Physical Mechanisms That Regulate Cell Viability in 3D Synthetic Hydrogels This study coordinates multiple cell-biomaterial interfaces to evaluate the overlapping physical signals of stiffness, solute transport, and cell confinement presented when cells are encapsulated in ...

Latest issue of curated #engineeredlivingmaterials feed:
biomed.news/bims-enlima/...

via @biomednews.bsky.social | #livingmaterials #ELMs

includes research on: tough hydrogels enabled by transient entanglements, physical mechanisms that regulate cell viability in 3D synthetic hydrogels, & more ๐Ÿงช

09.03.2026 09:56 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
Ultrafast-relaxing and photopolymerizable PEG hydrogels enable viscoelasticity-mediated cell remodeling in synthetic matrices Photopolymerizable BELA hydrogels combine dynamic boronate ester and elastic dithiolane-ene crosslinks to achieve ultrafast stress relaxation and tunable viscoelasticity. By adjusting formulation and ...

Latest issue of curated #engineeredlivingmaterials feed:
biomed.news/bims-enlima/...

via @biomednews.bsky.social | #livingmaterials #ELMs

includes research on: cell remodeling in synthetic matrices, designing self-healing, printable, and tough conductive hydrogels, matter and microbes & more ๐Ÿงช

09.03.2026 09:51 ๐Ÿ‘ 1 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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a cartoon character from the simpsons is making a funny face and says interesting ALT: a cartoon character from the simpsons is making a funny face and says interesting

#Autophagy and #mTOR papers from last week, worth a peek!

biomed.news/bims-auttor/...

08.03.2026 09:00 ๐Ÿ‘ 4 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0