Jenn Hammel

So proud of our lab and all the amazing science achieved last year!

Had an incredible time learning and networking at CAIRIBU this year. Such a warm welcome to the urology field!

Demonstration of chemotherapeutic-mediated changes in meningeal lymphatics in vitro, ex vivo, and in vivo - Communications Biology In vitro, ex vivo, and in vivo models reveal that taxane chemotherapy disrupts meningeal lymphatic barrier function and vessel structure, alongside changes in fluid flow and impaired cognition.

I'm delighted to share the latest pub from my PhD work! In this work, co-first authored by Monet Roberts and myself, we found that systemic taxane chemotherapy damaged the meningeal lymphatics using in vitro, ex vivo, and in vivo models ⬇️🧪

#scisky #academicsky

www.nature.com/articles/s42...

Very excited to work with Carmen this fall! 😊

Engineered lymphatic stroma model applications in central nervous system leukemia Central nervous system (CNS) involvement frequently occurs in acute lymphoblastic leukemia (ALL), but many questions remain about how leukemia cells access, persist in, and exploit the CNS. The CNS is...

Happy to share a new pre-print from my graduate work at VT! We tested how the engineered lymphatic stroma models I developed could be used to study central nervous system leukemia ⬇️🧪 #scisky

www.biorxiv.org/content/10.1...

Alongside that funding is extensive career development and connection with the benign urology community. I am thrilled for this next step in my scientific training! 🎉 🧪

Thank you to the program directors, Dr. Amundsen, Dr. Jayes, and Dr. Kameny for the opportunity!

obgyn.duke.edu/education-tr...

I'm very excited to share that I've been selected as a Duke University KURe Scholar! With this funding, I will study the long-term impacts of radiotherapy on the bladder using tissue engineering with the goal of understanding and treating radiation cystitis in cancer survivors #scisky

Postdoc @jennhammel.bsky.social representing the lab today at the 2025 North Carolina Postdoc Symposium at the NC Biotechnology Center. We have an incredible community of scientists here in NC! #scisky #academicsky 🧪🔬

Interstitial fluid flow in an engineered human lymph node stroma model modulates T cell egress and stromal change The lymph node (LN) performs essential roles in immunosurveillance throughout the body. Developing in vitro models of this key tissue is of great importance to

Very excited to share a new publication from my PhD work on our engineered lymph node stroma model! We saw flow-mediated changes to T cell egress and stroma morphology and inflammation 🧪🔬 @pompanolab.bsky.social
pubs.aip.org/aip/apb/arti... #scisky #immunoengineering

Scientists as political advocates Science, both teaching and doing, is under attack. The recent US presidential election of a person and platform with anti-science bias exemplifies this. The study of climate processes and patterns and...

If you can, do something, speak up and act up. www.science.org/doi/10.1126/...

Very excited to be starting my post doc at Duke with the Gerecht Lab! I'll be studying the dynamics of extracellular matrix and immune function #immunoengineering

Hi Erik! I'd like to be added. I'm a post doc in biomedical engineering at Duke University. Here's my ORCID page: orcid.org/0000-0001-56...

Figure from paper. (a) Immunofluorescence images of human tonsil, showing adjacent zones for T cells and B cells. (b) Schematic of T and B cell differentiation and interaction, leading to IgM production. (c) Schematic of a planar microfluidic chip with three adjacent lanes for cell-laden hydrogel, in which T cells and B cells can be loaded separately or mixed together.

My whole team is excited to share our preprint with you, on an #OrganOnChip model of T cell-B cell interactions in the human lymph node! This is a model of antibody production starting from naive T cells and B cells, in a 3D microenvironment. #immunoengineering

www.biorxiv.org/content/10.1...

Engineered human lymph node stroma model for examining interstitial fluid flow and T cell egress The lymph node (LN) performs essential roles in immunosurveillance throughout the body. Developing in vitro models of this key tissue is of great importance to enhancing physiological relevance in imm...

New pre-print! Check out our engineered lymph node stroma model. We showcase its applications in interstitial fluid flow and immune cell egress www.biorxiv.org/content/10.1...