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Yushan Wang

@yosh3118

PhD in Neuroscience, traumatic brain injury research scientist. Proud Canadian πŸ‡¨πŸ‡¦. Never had Covid, still trying hard to avoid it. Interested in all things medicine.

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23.11.2024
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Latest posts by Yushan Wang @yosh3118

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Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis - BMC Medicine Background Since its emergence in 2019, COVID-19 has continued to pose significant threats to both the physical and mental health of the global population, as well as to healthcare systems worldwide (...

In a review of 37 studies, encompassing 2,965,467 patients, 15% of Covid survivors suffered from cardiovascular sequelae. This underscores the risk of cardiovascular disease in #LongCovid

bmcmedicine.biomedcentral.com/articles/10....

08.02.2025 00:43 πŸ‘ 46 πŸ” 21 πŸ’¬ 1 πŸ“Œ 0

Covid and the thyroid ⚠️

A review of 53 studies sheds light on thyroid dysfunction in COVID-19-related disorders and #LongCovid, "underscoring the complex nature of SARS-CoV-2 infection and its far-reaching impacts on human health."

06.02.2025 09:55 πŸ‘ 250 πŸ” 50 πŸ’¬ 15 πŸ“Œ 12
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Does COVID increase the risk of Alzheimer’s disease? COVID-19, even in mild cases, is linked to changes in Alzheimer’s disease-related brain biomarkers comparable to four years of aging. This study raises concerns about long-term neurological risks and ...

Both mild and severe cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are linked to changes in brain biomarkers associated with Alzheimer’s disease.

But let’s keep getting it over and over right ?

www.news-medical.net/news/2025020...

03.02.2025 11:53 πŸ‘ 252 πŸ” 100 πŸ’¬ 11 πŸ“Œ 5

Patients with breakthrough infections exhibited a higher prevalence of pre-existing conditions such as anxiety, depression, and organ-specific comorbidities
” does this mean people with these pre-existing conditions were more susceptible to infection after vaccination?!

30.01.2025 12:42 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Neurologic Impacts of Long COVID, an Autoimmune Syndrome: Igor Koralnik, MD The chief of neuroinfectious diseases and global neurology at Northwestern Medicine talked about a relatively new autoimmune condition, marked by mitochondrial dysfunction. [WATCH TIME: 2 minutes]

www.neurologylive.com/view/neurolo...

30.01.2025 12:33 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Prior vaccination prevents overactivation of innate immune responses during COVID-19 breakthrough infection SARS-CoV-2 breakthrough infections in previously vaccinated individuals are characterized by reduced activation of innate immune responses.

A benefit of prior vaccination when there's a breakthrough infection: putting the brakes on a maladaptive innate immune response
www.science.org/doi/10.1126/...

29.01.2025 19:18 πŸ‘ 385 πŸ” 106 πŸ’¬ 10 πŸ“Œ 5
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Severity and Long-Term Mortality of COVID-19, Influenza, and Respiratory Syncytial Virus This cohort study assesses the severity and long-term mortality of COVID-19, influenza, and respiratory syncytial virus in a large cohort of nonhospitalized veterans.

Reminder:

CΓΆvid IS NOT the Flu

jamanetwork.com/journals/jam...

28.01.2025 09:48 πŸ‘ 146 πŸ” 51 πŸ’¬ 1 πŸ“Œ 3
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Long COVID Impairs Exercise Capacity and Cognition for Years - Neuroscience News A study of nearly 1,000 people with post-COVID-19 syndrome (PCS) revealed that two-thirds still experienced significant symptoms, including reduced exercise capacity and cognitive performance, two yea...

Long COVID Impairs Exercise Capacity and Cognition for Years.

"A study of nearly 1,000 people with post-COVID-19 syndrome (PCS) revealed that two-thirds still experienced significant symptoms, including reduced exercise capacity and cognitive performance, two years after infection."

24.01.2025 01:08 πŸ‘ 283 πŸ” 108 πŸ’¬ 7 πŸ“Œ 14
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Driving Under the Cognitive Influence of COVID-19: Exploring the Impact of Acute SARS-CoV-2 Infection on Road Safety | Neurology ObjectiveThis study evaluated the association between acute COVID-19 cases and the number of car crashes with varying COVID-19 vaccination rates, Long COVID rates, and COVID-19 mitigation strategies.B...

The study suggests that acute COVID-19, irrespective of Long COVID status, is associated with an increased risk of car crashes, likely due to neurological changes caused by SARS-CoV-2.

www.neurology.org/doi/10.1212/...

#LongCovid

19.01.2025 20:06 πŸ‘ 85 πŸ” 34 πŸ’¬ 4 πŸ“Œ 4
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Sweden’s controversial COVID-19 strategy: lessons from higher mortality rates Sweden's relaxed approach to COVID-19, emphasizing voluntary compliance and avoiding strict lockdowns, resulted in higher mortality rates compared to neighboring countries, despite preserving individu...

Sweden: "Not implementing a mandatory lockdown was blamed for the higher mortality seen in Sweden. In a modeling study... researchers found that the infection rates could have been reduced by 75% and mortality could have been reduced by 25%"

kevinmd.com/2025/01/swed...

21.01.2025 01:06 πŸ‘ 253 πŸ” 104 πŸ’¬ 2 πŸ“Œ 5

More evidence is coming up pointing to viral infections being connected with Alzheimer's and Parkinson's diseases. 2025 will be the neurovirology year!

14.01.2025 00:16 πŸ‘ 126 πŸ” 44 πŸ’¬ 3 πŸ“Œ 1
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Are some cases of Alzheimer's disease caused by infection? - Harvard Health Some scientists believe that microbes might play a part in Alzheimer's disease development. There are several theories about how and why this occurs. Microbes that might be involved include certain...

'The virus that causes COVID-19, known as SARS-CoV-2, may also make the brain vulnerable to Alzheimer's'.

It's very important to think through the population-level effects this will have in the next decade.

www.health.harvard.edu/mind-and-moo...

13.01.2025 16:48 πŸ‘ 527 πŸ” 184 πŸ’¬ 20 πŸ“Œ 16

Why am I watching the House of Cards?

11.01.2025 01:35 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Seems to me that microglia is also activated. There might be no increased staining in IBA-1, the cell body certainly looked out of shape of a normal microglia, based on my own limited experience.

10.01.2025 20:27 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

β€œHis brain was diagnosed as having chronic traumatic encephalopathy (CTE) - a form of degenerative disease dementia which is believed to be caused by repeated blows” the role of repetitive concussions, even sub threshold mild concussions, cannot be over emphasized for athletes!

10.01.2025 20:17 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Marked inflammatory response to ink of a tattoo

Marked inflammatory response to ink of a tattoo

How tattoo ink induces inflammation and impairs the response to a Covid vaccine
www.biorxiv.org/content/10.1...

04.01.2025 15:46 πŸ‘ 236 πŸ” 79 πŸ’¬ 13 πŸ“Œ 15

The answer is obvious now after five years of research.

02.01.2025 14:42 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Does COVID-19 damage the brain? - Harvard Health Most people who get COVID-19 don't suffer damage to the brain. But some do, and even people who initially get just mild COVID symptoms are vulnerable. COVID's potential to damage the brain is anoth...

www.health.harvard.edu/mind-and-moo...

02.01.2025 14:40 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Sleep microstructure organizes memory replay - Nature The temporal microstructure of the brain can multiplex distinct cognitive processes during sleep to support continuous learning.

Cornell University researchers have found the pupil is key to understanding how, and when, the brain forms strong, long-lasting memories.

"Sleep microstructure organizes memory replay: Pupil size in sleep reveals how memories are sorted, preserved." #Nature

www.nature.com/articles/s41...

02.01.2025 14:01 πŸ‘ 58 πŸ” 8 πŸ’¬ 0 πŸ“Œ 1
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Impact of coffee intake on human aging: Epidemiology and cellular mechanisms The conception of coffee consumption has undergone a profound modification, evolving from a noxious habit into a safe lifestyle actually preserving hu…

β˜•οΈπŸ’‘ Can coffee slow aging?

A new review shows that moderate coffee consumption may extend healthspan, reducing risks of chronic diseases like cancer, cardiovascular issues, & memory loss.

This could add up to 2 years to your life.

πŸ”— www.sciencedirect.com/science/arti...

#SciComm #Coffee πŸ§ͺ

02.01.2025 06:08 πŸ‘ 65 πŸ” 8 πŸ’¬ 8 πŸ“Œ 13

Albertans, please demand that your prov. govt. do everything they can to ensure Paxlovid is accessible. A bunch of us just had to call around to pharmacy after pharmacy to try and get some for a patient who needs it. She would have otherwise had to wait until Jan 2 - outside the window.
#abpoli

01.01.2025 02:43 πŸ‘ 144 πŸ” 49 πŸ’¬ 8 πŸ“Œ 3
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Does coffee prevent head and neck cancer?

"Coffee and tea consumption was linked with lower risks of developing head and neck cancers, including cancers of the mouth and throat."

Open Access
acsjournals.onlinelibrary.wiley.com/doi/full/10....

31.12.2024 00:20 πŸ‘ 43 πŸ” 10 πŸ’¬ 0 πŸ“Œ 3
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Original Article: Highly Pathogenic Avian Influenza A(H5N1) Virus Infections in Humans nej.md/3VU4R8I

Editorial: The Emerging Threat of H5N1 to Human Health nej.md/4fKc42s

Correspondence: Critical Illness in an Adolescent with Influenza A(H5N1) Virus Infection nej.md/4gR18Rt

#IDsky #MedSky

31.12.2024 22:05 πŸ‘ 89 πŸ” 44 πŸ’¬ 4 πŸ“Œ 11
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Fibrin drives thromboinflammation and neuropathology in COVID-19 - Nature Fibrin drives inflammation and neuropathology in SARS-CoV-2 infection, and fibrin-targeting immunotherapy may represent a therapeutic intervention for patients with long COVID.

🧠 How COVID-19 impacts the brain

Researchers found that blood clots linked to COVID-19 can cause inflammation and brain damage.

A new antibody treatment targeting these clots could help reduce long-term effects seen in long COVID.

πŸ”— www.nature.com/articles/s41...

#SciComm #COVID19 πŸ§ͺ

31.12.2024 11:42 πŸ‘ 134 πŸ” 52 πŸ’¬ 5 πŸ“Œ 5
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Lifetime depression, sleep disruption and brain structure in the UK Biobank cohort Whether depression and poor sleep interact or have statistically independent associations with brain structure and its change over time is not known. …

Lifetime depression and poor sleep independently link to reduced brain structure, with poor sleep worsening depression's impact on certain areas.

by Lyall LM, Stolicyn A (...) Smith DJ et 6 al. in J Affect Disord #MedSky

πŸ“– read the article:

31.12.2024 12:49 πŸ‘ 12 πŸ” 5 πŸ’¬ 0 πŸ“Œ 1
XEC Variant May Be Driving β€˜Silent’ COVID-19 Surge In December 2024

Bruce Y. Lee
Senior Contributor
Bruce Y. Lee, M.D., MBA, covers health, medicine, wellness and science
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Dec 28, 2024, 06:54am EST
Updated Dec 28, 2024, 07:00am EST

XEC Variant May Be Driving β€˜Silent’ COVID-19 Surge In December 2024 Bruce Y. Lee Senior Contributor Bruce Y. Lee, M.D., MBA, covers health, medicine, wellness and science Follow Dec 28, 2024, 06:54am EST Updated Dec 28, 2024, 07:00am EST

XEC Variant May Be Driving β€˜Silent’ COVID-19 Surge In December 2024.

"Not talking about COVID-19 doesn’t mean that it has gone away. The trouble, though, is many people are acting as if COVID has gone"

Source: archive.md/7mZaT

30.12.2024 00:37 πŸ‘ 156 πŸ” 55 πŸ’¬ 1 πŸ“Œ 3
https://diabetesjournals.org/diabetes/article/doi/10.2337/db24-0816/157642/SARS-CoV-2-Spike-S1-subunit-triggers-pericyte-and

SARS-CoV-2 spike S1 protein affects the pancreas's islet microvascular function in humans. This can contribute to dysfunction in the pancreas and the development of diabetes following SARS-CoV-2 infection

#LongCovid
t.co/0Edr2EPdJf

26.12.2024 22:04 πŸ‘ 119 πŸ” 61 πŸ’¬ 9 πŸ“Œ 4

Taxi and ambulance drivers exhibited the lowest Alzheimer's disease mortality rates among various occupations analyzed in the study.

by R Patel V, Liu M, Worsham CM and Jena AB in BMJ #MedSky

πŸ“– read the article: https://www.bmj.com/content/387/bmj-2024-082194

26.12.2024 04:32 πŸ‘ 16 πŸ” 3 πŸ’¬ 2 πŸ“Œ 0
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Can flashing lights stall Alzheimer’s? What the science shows Pulses of light and sound seem to have beneficial effects. But some argue it is too soon to market experimental devices.

Can flashing lights stall Alzheimer’s? What the science shows

Pulses of light and sound seem to have beneficial effects. But some argue it is too soon to market experimental devices.

www.nature.com/articles/d41...

26.12.2024 03:35 πŸ‘ 9 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0
schematic of how microvascular dysfunction can occur via the spike (S1) protein of SARS-CoV-2

schematic of how microvascular dysfunction can occur via the spike (S1) protein of SARS-CoV-2

Covid is associated with an increased risk of Type 2 diabetes www.thelancet.com/journals/lan... (one of many reports)
But the mechanism is unclear. A new report suggests islet microvascular dysfunction is a contributing factor
diabetesjournals.org/diabetes/art... open-access

24.12.2024 15:19 πŸ‘ 377 πŸ” 117 πŸ’¬ 9 πŸ“Œ 2