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Brent Stockwell

@brentstockwell

Chair, Dept of Biological Sciences, Columbia University. Metabolism; cell death; ferroptosis; lipids; chemical biology; cancer; neurodegeneration; spatial biology; drug discovery; AI

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16.11.2024
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Latest posts by Brent Stockwell @brentstockwell

Fundamental mechanism of ferroptosis: Three unanswered questions Ferroptosis, an iron-dependent form of regulated cell death (RCD) driven by lipid peroxidation, has been extensively studied since its conceptualization in 2012 and has been suggested as a therapeutic...

Here is reading for this snowy day: Congrats to Hanna Feinsod on publication of our perspective in Ferroptosis & Oxidative Stress on 3 major unanswered questions in #ferroptosis! www.sciexplor.com/articles/fos...

25.01.2026 14:22 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

The Columbia Dept of Biological Sciences is searching for an #Assistant #Professor with expertise in #Biochemistry. please apply and spread the word!
https://
apply.interfolio.com/179345

03.01.2026 16:56 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Lipidomic changes in persister cancer cells drive enhanced ferroptosis sensitivity Aims: Unique in the broader category of drug-resistant cells, persister cancer cells (PSs) acquire their tolerance to compounds through reversible, chromatin-mediated changes, allowing them to β€˜persis...

Congrats to Ed Reznik and the team on our paper "Lipidomic changes in persister cancer cells drive enhanced ferroptosis sensitivity" in the new journal Ferroptosis and Oxidative Stress! www.sciexplor.com/articles/fos... (free w/ no subscription no APCs)

15.11.2025 04:15 πŸ‘ 8 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Professor King understood that impactful researchers can benefit broader society by teaching about their #science, and that education is improved when we bring frontier research ideas in the classroom.

29.10.2025 17:03 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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I was honored to give the L. Carroll King Memorial Lectures at Northwestern University, sponsored by the Chemistry Department.

Professor King was a pioneering researcher and #teacher who joined Northwestern’s faculty in 1942. He was active in advancing ideas about chemical #education

29.10.2025 17:02 πŸ‘ 7 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

I’m excited to lead this new journal that will focus on how cells interact with their environment. We are assembling a top tier editorial board, key partnerships, and looking to be the primary forum for the rapidly growing field of spatial biology.

20.10.2025 12:13 πŸ‘ 9 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Brent Stockwell

Brent Stockwell

Congratulations to IICD member @brentstockwell.bsky.social who was awarded an NCI P01 grant with Xuejun Jiang (MSK) and Wei Gu (CUIMC).

Read more: cancerdynamics.columbia.edu/news/brent-s...

cc: @columbiacancer.bsky.social @mskcancercenter.bsky.social @columbiamed.bsky.social

14.10.2025 12:39 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Congrats to Jenny and Liam on our Prevew in Molecular Cell on the excellent paper by Yaqin Deng, Jin Ye et al in the same issue describing a new protection mechanism against #ferroptosis by #DHA β€” Here is a free download: authors.elsevier.com/a/1loAH3vVUP... @MolecularCell @Columbia

18.09.2025 15:22 πŸ‘ 6 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Thanks to James Olzmann and Scott Dixon for organizing a fantastic #faseb #ferroptosis meeting in Scottsdale AZ! Lots of great science as ferroptosis continues to impact diverse biology and diseases. Can’t wait for the next one! @olzmannlab.bsky.social

31.07.2025 18:42 πŸ‘ 27 πŸ” 9 πŸ’¬ 1 πŸ“Œ 0
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LIMD1 Loss Confers a GPX4-Dependent Cell State in Lung Cancer LIMD1 (LIM domains containing 1) is a bona-fide tumour suppressor gene frequently lost during the early stages of non-small cell lung cancer (NSCLC) development, resulting in a worse outcome for LIMD1...

Congrats to Tyson Sharp and his colleagues on the bioRxiv paper on LIMD1 loss conferring #GPX4 sensitivity in lung cancer. An important #cancer #ferroptosis study.

www.biorxiv.org/content/10.1...

11.06.2025 18:40 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

It was great fun to be there!

04.06.2025 18:12 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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22.05.2025 01:18 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Here is our latest paper in @ACSBiol on compounds that restore activity to the R152H GPX4 variant, found in patients with SSMD. Congrats to Hengrui, Farhad and Russ on a great collaboration! @columbia #ferroptosis pubs.acs.org/doi/full/10....

08.05.2025 12:28 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
IICD May newsletter

IICD May newsletter

πŸ“’ The May IICD newsletter is live! Highlights include CINnerβ€”our new tool in @plos.org by @khanhndinh.bsky.social lab, #CancerResearchMonth spotlights on @brentstockwell.bsky.social & Yue Wang, and recent achievements from our community.πŸ”— Read the full issue: bit.ly/43fNAe7

05.05.2025 15:00 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

It was a true pleasure to visit such an outstanding group of faculty and students! Can’t wait to see all the great discoveries that will emerge from the #moleculartherapeutics division

04.05.2025 11:39 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Brent Stockwell

Brent Stockwell

πŸ”¬ During #CancerResearchMonth, we’re spotlighting @brentstockwell.bsky.social, exploring ferroptosis as a powerful way to eliminate aggressive cancers. His latest work links diet and cancer treatment: bit.ly/4iNEWc5 @columbiacancer.bsky.social @columbiamed.bsky.social @columbiasysbio.bsky.social

01.05.2025 14:46 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
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Looking forward to hosting the first #ferroptosis cancer symposium at #AACR25 in 30 minutes. Join us in person or online!

30.04.2025 14:46 πŸ‘ 10 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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#FOLSCR is a new conference exploring all aspects of a form of cell death that results from iron accumulation and lipid peroxidation. Hear keynotes @ginadenicola.bsky.social and @brentstockwell.bsky.social with organizers Scott Dixon and @olzmannlab.bsky.social. Save your space: buff.ly/MmJsYQq

25.04.2025 14:56 πŸ‘ 5 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Congratulations Dean Gonzalez!

13.03.2025 10:35 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Only 4 days left to register. I hope to see many new ferroptosis researchers in Chicago!

08.03.2025 12:20 πŸ‘ 2 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Final deadline is imminentβ€”last chance to join us in Chicago!

06.03.2025 15:32 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Only a few days left to register. We are loving the abstracts you are submitting!

01.03.2025 12:59 πŸ‘ 1 πŸ” 3 πŸ’¬ 0 πŸ“Œ 2

Only a few days left to register. We are loving the abstracts you are submitting!

01.03.2025 12:59 πŸ‘ 1 πŸ” 3 πŸ’¬ 0 πŸ“Œ 2

Come join us in Chicago!

28.02.2025 11:07 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Thank you @senkalce.bsky.social for hosting me for a fantastic visit at VCU! What an impressive group of faculty and students doing impactful science

28.02.2025 01:22 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

It was great to meet you @pauladbos.bsky.social and spend time at VCU!

28.02.2025 01:20 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

A few more days left to register!

26.02.2025 10:56 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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We extended the deadline on the #Chicago #ASBMB #Ferroptosis meeting! 12 short talks will be selected from the abstracts. Register for what we expect to be a great conference! www.asbmb.org/meetings-eve...

24.02.2025 18:41 πŸ‘ 11 πŸ” 6 πŸ’¬ 0 πŸ“Œ 3
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We extended the deadline on the #Chicago #ASBMB #Ferroptosis meeting! 12 short talks will be selected from the abstracts. Register for what we expect to be a great conference! www.asbmb.org/meetings-eve...

24.02.2025 18:41 πŸ‘ 11 πŸ” 6 πŸ’¬ 0 πŸ“Œ 3
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Our first paper of #2025! We identified viral-selective, non-covalent inhibitors of #coronavirus #3CL main #protease using a DNA-encoded library, and optimized them using x-ray crystallography. www.nature.com/articles/s41...

03.01.2025 14:28 πŸ‘ 18 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0