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Lionel Guy

@lionelguy

Evolutionary microbiologist. Host adaptation, endosymbionts, Legionella. Associate prof at Uppsala University. https://www.uu.se/en/department/medical-biochemistry-and-microbiology/research/guy-lionel

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23.10.2023
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Latest posts by Lionel Guy @lionelguy

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Host-Specific Adaptation of Legionella pneumophila to Single and Multiple Hosts Abstract. Legionella pneumophila is an endosymbiotic bacterial species able to infect and reproduce in various protist and human hosts. Upon entry into hum

Moreno, @lionelguy.bsky.social et al. applied experimental evolution to identify genes conferring host specificity to L. pneumophila, highlighting the importance of mutations targeting the LerC protein and the LPS synthesis cluster.

πŸ”— doi.org/10.1093/molbev/msaf161

#evolbio #molbio #legionella

05.08.2025 17:24 πŸ‘ 7 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0

Nice to have you here, thanks for a great presentation!

20.01.2025 14:20 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Host-bacteria interactions: ecological and evolutionary insights from ancient, professional endosymbionts Abstract. Interactions between eukaryotic hosts and their bacterial symbionts drive key ecological and evolutionary processes, from regulating ecosystems t

"I need to read more about evolution of host adaptation, why don't we write a review", said ZΓ©lia Bontemps a week after starting in my lab. Well, proud to announce that said review (also with Kiran Paranjape) is out in FEMS Reviews Microbiology academic.oup.com/femsre/advan...

06.08.2024 14:43 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
PhD student in evolutionary genomics of symbiotic bacteria and their hosts - Uppsala University, Sweden PhD student in evolutionary genomics of symbiotic bacteria and their hosts, Uppsala University, Department of Cell and Molecular Biology, Uppsala University

Are you interested in how co-evolution shapes the genomes of bacterial symbionts and their hosts? I have an open PhD position in my lab at Uppsala University to work on evolutionary genomics of host-symbiont interactions, with focus on #Wolbachia and #Drosophila. Apply at

02.05.2024 07:23 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
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PhD student position in bioinformatics/evolutionary microbiology The Department of Medical Biochemistry and Microbiology (IMBIM) at Uppsala University provides a broad international environment for research and teaching. Research at IMBIM) broadly spans the areas o

Job alert (pls RP): an exciting PhD student position in evolutionary microbiology available in my lab at Uppsala University! Help us study the evolution of early intracellular bacteria and what they can tell us about their first hosts. Apply before April 8th
uu.varbi.com/en/what:job/...

06.03.2024 12:04 πŸ‘ 5 πŸ” 7 πŸ’¬ 0 πŸ“Œ 1

Fantastic!

24.11.2023 07:06 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0