Scott Biering

Our lab at UCSD @ucsdimmunology.bsky.social is working to discover new viral toxins and understand how they contribute to disease and infection. Thanks to @yountlabosu.bsky.social for the invitation and co-authors @vasiliya-kril.bsky.social, Eva, Henry, and @fpahmeier.bsky.social.

The contribution of viral toxins to infection and pathogenesis | mBio Viral pathogenesis is a complex process involving both the virus and the host. Tissue damage caused during viral infection can result from the virus and/or the host immune response. A prerequisite for...

Excited to share our new review article published today in @mbio.bsky.social discussing the role of viral toxins in viral pathogenesis and dissemination. We summarize our recent work and current literature on flavivirus NS1, SARS-CoV-2 Spike, CCHFV GP38, and EBOV GP. journals.asm.org/doi/10.1128/...

I am REALLY excited to share this manuscript from my group now on bioarxiv. Here we used the OAA lectin scaffold to ask can lectins be evolved to have specific interactions for defined glycan structures . www.biorxiv.org/content/10.6...

Max Fels @mfels.bsky.social from our lab discovers giant DNA viruses that infect amoeba encode eIF4E and the entire suite of 4F complex proteins to control mRNA translation, including beautiful crystal structures of viral 4E bound to modified mRNA 5' caps:

www.cell.com/cell/fulltex...

The giant viruses surprised us at almost every turn of this project, but ultimately led us down a very rewarding path. Happy to share this work is now available online 🧪

Prof. Claudia Nunes Duarte dos Santos (Fiocruz, Brazil) will present the discovery of Pirahy virus—a newly identified alphavirus from Brazilian mosquitoes with features suggesting emergence potential.
Thursday 19th Feb by Zoom.
All welcome! Just DM your email for the link.

Excited to share our work on #AncientRNA from alcohol-preserved lungs, recovering the oldest human RNA virus genome (an 18th-century rhinovirus). Our study shows that viral RNA remnants persist in centuries-old tissue, opening new ways to study virus evolution and historical disease #Paleovirology🫁🦠

a black cat is using an apple laptop with the words deadline is coming written below it Alt: a black cat is using an apple laptop with the words deadline is coming written below it

🚨ABSTRACT DEADLINE FEBRUARY 2🚨
🚨TRAVEL AWARD DEADLINE FEBRUARY 9🚨

Share your virology research by submitting an abstract for ASV 2026 by 11:59pm Eastern on Monday 2/2/26

Need financial support? Trainees & teachers can apply for travel awards

www.asv.org/abstract-sub...
www.asv.org/travel-awards

Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...

🔬 Call to create junior research groups at the Institut Pasteur

Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies

📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD

Apply now 📝 research.pasteur.fr/en/call/crea...

#JobOpportunity #Research

Job alert! Assistant professor position in the Department of Molecular Genetics (University of Toronto). Amazing department and city. jobs.utoronto.ca/job/Toronto-... Please share.

We are hiring new faculty!! Come join our amazing community in the Department of Molecular Microbiology at Washington University School of Medicine! The deadline for applications is 2/21, but applications will be reviewed on a rolling basis. facultyopportunities.wustl.edu/Posting/Deta...

We are excited to share our new @CellCellPress paper revealing mechanisms of action of promising drugs against the helicase-primase of herpes simplex virus 1 (HSV-1) 🤩 harvardvirology.bsky.social www.cell.com/cell/fulltex...

Pediatric Infectious Diseases/Microbiology - Professor Series (tenure track/tenure), Open Rank University of California, Irvine is hiring. Apply now!

🚨New faculty job opportunity 🚨

Please share this ad for a faculty position in our department at UC Irvine, in the fields of microbiology and infectious disease. MD/PhDs and PhDs are desired and should apply!

recruit.ap.uci.edu/JPF09954

Dear network, I’m pleased to announce the launch of hashtag#DeZi (Dengue and Zika Immunology and Genomics Multi-Country Network) – a global collaboration that I’m part of, bringing together leading teams across Africa, Asia, and the Americas to advance our understanding of dengue and Zika viruses. 🔬 DeZi in brief: DeZi is a global initiative led by Imperial College London and Nuno R. Faria and supported by the Wellcome Trust, Temasek Foundation and the National Environment Agency. It integrates genomics, serology, and modelling to map the burden, transmission, and evolution of dengue and Zika viruses. By combining innovation with equitable partnerships, DeZi aims to: • accelerate the adoption of improved diagnostics • strengthen regional laboratory capacity and South–South collaborations • enhance preparedness for future arboviral epidemics in a changing climate With its open-access resources and policy engagement activities DeZi will help countries integrate the surveillance of dengue, Zika, and other mosquito-borne viruses into routine national health systems, turning collaboration into capacity, and data into effective policymaking. 🌍 Partners span research institutions and public-health laboratories in more than 15 countries across Africa, Asia, and Latin America, working closely with UKHSA, Yale University, WHO, and networks such as UNITEDengue, CREID, and ARTIC2.0.

I’m pleased to announce the launch of #DeZi ! a global collaboration funded by @wellcometrust.bsky.social and led by @imperialcollegeldn.bsky.social that brings together teams across Africa, Asia & the Americas to advance our understanding of #dengue & #Zika viruses

Thread DeZi in brief 👇

Careers Minimum qualifications:PhD, MD, or equivalent in a relevant field of study, plus applicable postdoctoral experience.

Excited to announce that we have a new faculty search opening in the Department of Microbiology and Immunology at the University of Minnesota for a tenure track Assistant Professor in RNA Virology. More info can be found here: hr.myu.umn.edu/jobs/ext/365...

Assistant Professor in Structural Biology and Biochemistry, Department of Molecular Biology & Biochemistry University of California, Irvine is hiring. Apply now!

Our home department of Molecular Biology & Biochemistry at UC Irvine is looking to hire a new tenure-track assistant professor in the broad area of structural biology. Come be our colleague! recruit.ap.uci.edu/JPF09887

Please apply and/or share this post.

New York Confirms State’s First Locally Acquired Case of Chikungunya

www.nytimes.com/2025/10/14/n...

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

Cohousing or cross-fostering followed by cohousing does not normalize the microbiomes of genetically distinct adult mice Lietuvninkas et al. use state-of-the-art gnotobiotic approaches to investigate whether cohousing or cross-fostering overpower the role of genetics in shaping the fecal bacterial commensal population. ...

I’m excited to share our latest work! We challenge the widely thought notion that cohousing and cross-fostering can normalize the microbiomes of genetically distinct mice: www.cell.com/cell-reports... 🐁🦠🧬

Human MX1 orchestrates the cytoplasmic sequestration of neosynthesized influenza A virus vRNPs | PNAS Interferon-inducible Myxovirus resistance 1 (MX1) proteins are known to restrict influenza A virus (IAV) transcription/replication process. Herein,...

After years in the making, Joe McKellar @viroscope.bsky.social’s final PhD paper is finally out today in PNAS! 🎉 🎉🎉
www.pnas.org/doi/10.1073/...

The NIH ordered me to stop my ‘dangerous’ gain-of-function research. It isn’t dangerous at all Safe gain-of-function research is necessary to identify new treatments for diseases like for tuberculosis — but the NIH has imposed unfounded stops.

Timely piece on the importance and safety of “gain-of-function” research, from my brilliant PhD advisor Sarah Stanley www.statnews.com/2025/10/06/g...

Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404

UMass Amherst Microbiology is hiring a tenure-track virologist. Come work with me! 🦠🧪
careers.umass.edu/amherst/en-u...

We are currently in the process of recruiting a technician. 🥼🐭🔬

If you know anyone with enthusiasm to learn new skills and stamina to hear me go on and on about IFNs, please have them reach out to me for more details!

Actively looking for a postdoc interested in host-virus evolution. Please apply to the #MahanFellowship This fellowship provides early career scientists with the opportunity to join a Fred Hutch CompBio lab (like ours!). If interested please contact me to coordinate proposal and apply by Dec 05 2025

From Megan Hayes' elegant PhD thesis, Cressida Madigan Lab UCSD Biological Sciences, using zebrafish model

In TB meningitis, mycobacteria lodge at vessel bifurcations, enlarge vessels, and transiently block brain blood flow—driving oxidative stress and cell death!

journals.plos.org/plosone/arti...

Neutrophils secrete exosome-associated DNA to resolve sterile acute inflammation | Nature Cell Biology Acute inflammation, characterized by a rapid influx of neutrophils, is a protective response that can lead to chronic inflammatory diseases when left unresolved. We previously showed that secretion of LTB4-containing exosomes via nuclear envelope-derived multivesicular bodies is required for effective neutrophil infiltration during inflammation. Here we report that the co-secretion of these exosomes with nuclear DNA facilitates the resolution of the neutrophil infiltrate in a mouse skin model of sterile inflammation. Activated neutrophils exhibit rapid and repetitive DNA secretion as they migrate directionally using a mechanism distinct from suicidal neutrophil extracellular trap release and cell death. Packaging of DNA in the lumen of nuclear envelope-multivesicular bodies is mediated by lamin B receptor and chromatin decondensation. These findings advance our understanding of neutrophil functions during inflammation and the physiological relevance of DNA secretion. Arya et al. report

Neutrophils release exosome-associated nuclear DNA to help resolve acute inflammation, preventing chronic disease progression. 🧬🔥 PMID:40404894, Nat Cell Biol 2025, @NatureCellBio https://doi.org/10.1038/s41556-025-01671-4 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

We’re back with another season of monthly seminars bringing together diverse and leading investigators worldwide to share cutting-edge arbovirus science.
🧬 Topics span molecular virology, virus–vector interactions, epidemiology, pathogenesis, and more.
📅 3rd Thursday each month
🕚 11 AM US ET Zoom

Cardioprotective effects of AMPK activation in H1N1 influenza virus infection Cardiac complications are among the most common and severe extrapulmonary manifestations of influenza virus infection, yet they are rarely recapitulated in mouse models without immunodeficiency. We fo...

🚨🚨Our new preprint establishes the first robust model of severe influenza cardiac complications in WT immunocompetent mice. Heart transcriptomics implicated a potential therapeutic metabolic intervention that indeed shows beneficial heart/survival effects. 🦠🧫🧬🫁🫀🐀
www.biorxiv.org/content/10.1...

I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions.

Descriptions and links in the following two posts.