Open postdoc position in immunology focusing on ILC3s and gut immunity at UMass Chan!
careers-umms.icims.com/jobs/49293/p...
17.02.2026 23:30
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Open postdoc position in immunology focusing on ILC3s and gut immunity at UMass Chan!
careers-umms.icims.com/jobs/49293/p...
At what point do we simply call these cells a subset of ILC3? They are more similar to ILC3s developmentally, phenotypically, and functionally than to DCs anyways.
www.science.org/doi/10.1126/...
Figure S7 with panels A through UU
Wow this is a seriously serious supplementary figure from @cellpress.bsky.social today. Panels A through UU.
I get that Cell likes to minimize the number of supplementary figures. But is this really what is happening here?
www.cell.com/cell/fulltex...
Microglial cGAS-STING-TBK1 activation in paraventricular thalamus mediates sleep and emotional disturbances in lupus mice www.sciencedirect.com/science/arti...
'We also show that LOY in T cells in the TME can affect cancer mortality in patients. Given the prevalence of LOY in healthy older men, these findings may also have implications for tumour-infiltrating Tβcell & chimeric antigen receptor Tβcell therapies.'
#Immunology #Immunotherapy
'Now, a report by Gustafsson et al. in Nature Biotechnology has identified a subset of thymic mesenchymal cells (ThyMCs) that drives thymic regeneration and harnessed these cells to restore immune function in mice after hematopoietic stem cell transplantation.'
www.nature.com/articles/s41...
Feel better during the day than at night during #influenza? Find out the βRole of IL-10 signaling in the #circadian control of host response to influenza infectionβ www.mucosalimmunology.org/article/S193...
Therapeutic VEGFC treatment protects against traumatic brain injury-driven tauopathy pathogenesis @cp-cellreports.bsky.social
www.sciencedirect.com/science/arti...
A Bluesky tweet: βJust remember that given the abundance of neurodivergent people in science, itβs far more likely that autism causes vaccines.β
A paper in Nature reports that mRNA vaccines targeting SARS-CoV-2, COVID-19, also sensitize tumours to immune checkpoint inhibitors. #medsky π§ͺ
Review @natimmunol.nature.com
Antigen-presenting cells as arbiters of mucosal tolerance and immunity
www.nature.com/articles/s41...
6/6 From what I've seen, many institutions have also noticed this shift and are focusing resources on these technological developments for the sake of developing treatments and undertaking research that is heavily transnational in lieu of basic science.
5/6 So what will future Nobels look like? It seems to me that, eventually, the age of discovery will end and be replaced with an age of innovation in which much of the most impactful research will be focused on the development of new technologies rather than discovery of a new protein or cell type
4/6 In addition, we now integrate multiple systems within each research project (e.g. neuro-immune, cancer-metabolism, cancer-immunology, etc.) and are studying interactions between cell types and, again, context-dependent functions, which do not generally get awarded the Nobel.
3/6 With the current methodologies, much of the research is focused on determining how different cell states and context-dependent functions of cells impact health, but these types of discoveries, although important, do not usually lead to paradigm shifting advances in the field warranting the Nobel
2/6 Today, with the spread of omics technologies, we have essentially already established what cells exist and have an idea of their overall functions. We will no longer be able to look at a disease, or a classification of diseases, and pin the blame on a new cell type. Problems are more complex.
1/6 With recent excitement around the #NobelPrize announcements, I think it's worth thinking about what the prize will look like in the future, especially for physiology and medicine. What happens when thereβs nothing left to discover in medicine? Have we already picked the low-hanging fruit?
Tregs have been one of the central pillars of the field of immunology. It was only a matter of time before these contributions won the #NobelPrize. Much deserved!
www.nature.com/articles/d41...
The fact that public funds are used to publish publicly funded research in journals owned by private publishers, who then sell access to that research at ridiculous prices to entities that buy it with more public funds, is kind of insane.
"The bill approved today by the Senate Committee on Appropriations includes $47.2 billion for NIHβs base budget, or about 1% more than this year."
www.science.org/content/arti...
"The U.S. Department of Health and Human Services (HHS) today announced the beginning of a coordinated wind-down of its mRNA vaccine development activities...."
cc: Sen. Bill Cassidy
Genome Sciences is looking for a Director of Departmental Computing. This is a rare opportunity for someone interested in leading our excellent IT team, building and maintaining computational infrastructure, and working closely with our faculty and labs uwhires.admin.washington.edu/ENG/candidat...
Utility of transgenic hematopoietic stem cell to generate a self-renewing source of tumor-specific cellular immunotherapy in human participants @natcomms.nature.com
www.nature.com/articles/s41...
π New paper alert. We benchmarked Visium, GeoMx, and Chromium for FFPE tumor analysis. Thanks @estellayixingdong.bsky.social for pushing this forward, & MOSAIC collaborators!
π www.nature.com/articles/s41...
#SpatialTranscriptomics #CancerResearch cc: @owkin.bsky.social @10xgenomics.bsky.social
Congrats to Wenqing on another wonderful paper that came out today in #Immunity!
www.sciencedirect.com/science/arti...
Thrilled to share our latest review on how the gut microbiome connects diet to health, now published in Nature Reviews Gastro & Hepa! Honored to co-sign this piece with outstanding PIs @eranelinav.bsky.social @jfcryan.bsky.social Yolanda Sanz MΓ©lanie Deschasaux Rebekka Lambrecht rdcu.be/epret
Congrats to my good friend Shruti Sharma!
STING, provides essential protection against blood-brain barrier breaches and neuromotor deficits during physiological aging
@cp-cellreports.bsky.social
cell.com/cell-reports...
Postdoc positions available studying how niche cells drive GI diseases!
robertsinstitute.weill.cornell.edu/faculty/goto...
'However, we now report that food-specific pTreg cells are exclusively induced by the recently identified RORΞ³t APCs4β8 and not by cDCs. Instead, our data suggest that pTregβcDC1 interactions in steady-state limit the expansion of food-specific CD8Ξ±Ξ² T cells.'
www.nature.com/articles/s41...