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Tamara de Kloe

@tamaradekloe

PhD Statistical Imaging Neuroscience | Working on time-varying functional connectivity methodology in fMRI @DondersInstitute

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Latest posts by Tamara de Kloe @tamaradekloe

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New paper in Imaging Neuroscience by TJ de Kloe, CF Beckmann, et al:

Time-resolved instantaneous functional loci estimation (TRIFLE): Estimating time-varying allocation of spatially overlapping sources in functional magnetic resonance imaging

doi.org/10.1162/IMAG...

02.07.2025 05:28 ๐Ÿ‘ 4 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

TRIFLE extends the Temporal Functional Modes framework (Smith et al., 2012) by capturing time-varying changes in spatial source allocation associated with various temporal functional modes.
#fMRI #Methdology #Neuroimaging #SpatialOverlap #ICA #DynamicConnectivity #TimevaryingConnectivity #TRIFLE

30.06.2025 17:33 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Assessing spatial and temporal connectivity dynamics in fMRI is methodologically challenging due to the noise in both domains. Therefore, we propose that it can be described by fixed spatial and temporal components that interact via time-varying linear mixing.
๐Ÿ‘‰ Continues in next comment.

30.06.2025 17:33 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

TRIFLE is an ICA-based method for time-varying functional connectivity in fMRI that allows for spatial overlap โ€” i.e., brain regions participating in multiple functional processes.
๐Ÿ‘‰ Continues in next comment.

30.06.2025 17:33 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Preview
Time-resolved instantaneous functional loci estimation (TRIFLE): Estimating time-varying allocation of spatially overlapping sources in functional magnetic resonance imaging Abstract. In functional magnetic resonance imaging, multivariate proxies of functional brain networks are commonly extracted using spatial independent component analysis. The theoretical premises of s...

๐ŸŽ‰ New paper out!
We present TRIFLE: Time-Resolved Instantaneous Functional Loci Estimation for fMRI.

๐Ÿงต In comments
๐Ÿ”— doi.org/10.1162/IMAG...
๐Ÿซ Donders Institute (@dondersinst.bsky.social)
๐Ÿง‘โ€๐Ÿ”ฌ Zahra Fazal, Nils Kohn (nilskohn.bsky.social), David Norris, Ravi Menon, Alberto Llera & Christian Beckmann

30.06.2025 17:32 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 0

TRIFLE extends the Temporal Functional Modes framework (Smith et al., 2012) by capturing time-varying changes in spatial source allocation associated with various temporal functional modes.
#fMRI #Methdology #Neuroimaging #SpatialOverlap #ICA #DynamicConnectivity #TimevaryingConnectivity #TRIFLE

30.06.2025 17:25 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Assessing spatial and temporal connectivity dynamics in fMRI is methodologically challenging due to the noise in both domains. Therefore, we propose that it can be described by fixed spatial and temporal components that interact via time-varying linear mixing.
๐Ÿ‘‰ Continues in next comment.

30.06.2025 17:24 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

TRIFLE is an ICA-based method for time-varying functional connectivity in fMRI that allows for spatial overlap โ€” i.e., brain regions participating in multiple functional processes.
๐Ÿ‘‰ Continues in next comment.

30.06.2025 17:23 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
Nils Kohn (@nilskohn.bsky.social) psychologist, neuroscientist interested in memory & emotion in health and education, VR for education, father of 2. https://www.ru.nl/en/departments/donders-community-for-medical-neuroscience/memory-e...

With co-authors:
Zahra Fazal,
Nils Kohn (nilskohn.bsky.social),
David Norris,
Ravi Menon,
Alberto Llera &
Christian Beckmann

30.06.2025 17:20 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0