Peter 't Hart

Doctoral Research Associate (Wissenschaftliche*r Mitarbeiter*in,salary level E 13 TV-L)

New PhD opportunity in the 't Hart group! We are looking for a candidate interested in using a chemical biology approach to study mRNA degradation. The project will focus on AI-generated peptide inhibitors to study mRNA deadenylation.

stellen.uni-muenster.de/jobposting/7...

PhD Position in Peptide-Based Drug Discovery (Industry Collaboration, w/m/d)

We are hiring! Check out our open PhD position for an exciting industry collaboration with Novo Nordisk:
jobs.ethz.ch/job/view/JOP...

Single atom substitutions in backbone aromatic groups alter membrane permeability and biological activity of cyclic peptides Cyclic peptides hold significant potential as disruptors of challenging targets such as protein-protein interactions, but their poor membrane permeability often limits their use for intracellular targ...

My first post here on Bluesky! Highlighting our preprint looking at how backbone modifications influence cyclic peptide cell uptake. Turns out it is a balancing act between uptake and biological activity. Great work by first author Joseph Openy and of course all others!
chemrxiv.org/engage/chemr...

Thanks for highlighting my switch to this platform @stephanhacker2.bsky.social!