Scott Nelson

Resurrecting Ancient DNA

Iowa State assistant professor @swnisu.bsky.social‬ is using AI to resurrect ancient enzymes, and he’s posting live updates on ResearchHub, as it happens.

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ResearchHub | Open Science Community We're a community seeking to improve prioritization, collaboration, reproducibility, and funding of scientific research. Discuss and discover academic research on ResearchHub

If you are interested in taking a look at the pre-registration you can find that here: doi.org/10.55277/Res... and the paper that it is based on can be found here: doi.org/10.55277/Res...

Follow along with an open science project on antimicrobial peptide discovery! I'm sharing all data and research notes publicly (doi.org/10.55277/Res...). Our pre-registration, funded through @researchhubf.bsky.social, builds on a recent paper published in their new Journal. 🧪

Peer review is meant to prevent scientific misconduct. But it has its own problems The peer review process is central to science – but it can be easily manipulated. Improving it is vital to uphold research integrity.

"Peer review is the worst method of safeguarding scientific integrity, except for all those other methods that have been tried from time to time." As Churchill might have said if he'd been a scientist rather than a politician.

From a conversation with a friend: 🧪🧵

I never knew there was a specific name for a triple spiral! The authors should have used this instead of 'tumbleweed'.

If you are interested and want to provide a review of this manuscript (and maybe earn some $), check out this post. bsky.app/profile/rese...

I was curious about the speed of the motor so I asked AI to do some calculations. The step length is about 15 nm and the authors suggest a speed of 10-20 nm is achievable. If you normalize that speed to "body length" it's about 2X faster than a human's walking speed. Not bad.

Here's a very cool paper from @biorxiv-biophys.bsky.social I shared on ResearchHub this week. The authors designed a three-legged motor protein that can walk down DNA in either direction. www.researchhub.com/paper/930685... 🧪 @researchhubf.bsky.social

‘Stamp out paper mills’ — science sleuths on how to fight fake research A group of scientists who are experts at spotting fraudulent research outline five essential steps to combat industrialized scientific misconduct.

‘Stamp out paper mills’ — science sleuths on how to fight fake research
A group of scientists who are experts at spotting fraudulent research outline five essential steps to combat industrialized scientific misconduct.

www.nature.com/articles/d41...

How Do We Democratize Scientific Research? Opinion | As scientists struggle to connect with the public, they must consider new models for making research more accessible.

Interesting article in @undark.org today about increasing public participation in science. undark.org/2025/01/10/o... 🧪

ResearchHub | Open Science Community We're a community seeking to improve prioritization, collaboration, reproducibility, and funding of scientific research. Discuss and discover academic research on ResearchHub

Hi Erik, I would like to be added to the Science feed. thanks!

www.researchhub.com/author/6328170