Cell cycle-dependent TICRR/TRESLIN and MTBP chromatin binding mechanisms and patterns - Genome Biology Background The selection of replication origins is a defining characteristic of DNA replication in eukaryotes, yet its mechanism in humans has not been well defined. Potential DNA replication origins ...

I’m excited to share a new paper from our lab, led by PhD student Tyler Noble.

This research deepens our understanding of how the genome is faithfully duplicated and sheds light on how these mechanisms can fail in diseases like cancer and congenital disorders.