Alexander Sever

Human cells for human proteins: Isotope labeling in mammalian cells in suspension for functional NMR studies In biological and biomedical research, the focus progressively moves towards difficult human proteins, which often can only be expressed in higher eukaryotic cells. Nuclear magnetic resonance (NMR) c...

Now out! Methods for isotope labeling in mammalian cells for NMR studies of difficult-to-produce proteins onlinelibrary.wiley.com/doi/full/10....

Join 2026 BPS Lecturer Lewis Kay on Tuesday, February 24, 2:00 PM - 3:00 PM at #bps2026 for an informal discussion. Dr. Kay will share insights from his scientific career—from pioneering discoveries to lessons learned along the way—and reflect on how the field continues to evolve

The BEST-HMBC-HMQC experiment for pairing geminal methyl groups in Valine and Leucine side-chains. Methyl groups are essential probes for characterising interactions and dynamics in large proteins. HN-based triple-resonance NMR experiments are often too insensitive for methyl assignments, making a ...

Preprint, The BEST-HMBC-HMQC expt for pairing geminal methyl groups in Valine and Leucine side-chains. Ana P.A. Alva, Lucas Siemons, Ulric le Paige, Coline Wiame, Florence Cordier, Nicolas Wolff, Guillaume Bouvignies, Philippe Pelupessy, Fabien Ferrage chemrxiv.org/engage/chemr... #NMRchat #NMR 🧲

Kay Lab is now live on 🦋

bsky.app/profile/lek-...

Diagram for a helium recovery system

The helium recovery system is now fully functioning in Lumigen’s #NMR facility! With this system, helium will be captured, purified, and stored for reuse in our NMR facility and can be used for other instruments, such as mass spectrometers.

Say no more!

One like & I’ll migrate the Kay lab account to BlueSky!

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