Collaboration between HF clinicians, investigators, entrepreneurs & investors is key to solving unmet needs. Venture-backed innovation has driven advances from meds to devices, permitting HF cardiologists to shape patient-centric diagnostics & therapies.
π https://bit.ly/4qX4KWU
An π online, asynchronous curriculum improved critical-care traineesβ knowledgeπ of MCS devices, beyond what clinical exposure alone provided. Gains were strongest for LVAD management. Next step is assessing knowledge transfer into clinical settingπ₯.
π https://bit.ly/3NWnF5Z
New science π¨! In pts on pV-A ECMO, 20% developed de novo AF β€οΈβπ©Ή. dnAF was linked to longer ECMO duration (6.4 vs 3.6 days) & β¬οΈpost-decannulation in-hospital mortality (33% vs 20%). PADP elevation trended toward β¬οΈdnAF risk.
π https://bit.ly/4r5dkTx
Analyzing HFrEF & HFmrEF pts from the TriNetX cohort, metoprolol succinate was associated with β¬οΈ event-free survival than tartrate, driven by β¬οΈ hospitalizations & deaths. Results support guideline preference for succinate due to more consistent Ξ²1 blockade.
π https://bit.ly/4jO2oau
A HFrEF polypillπ could β¬οΈ GDMT uptake, but prescriber prefs are unknown. Using a 5-stage mixed-methods process, researchers built a discrete choice experiment to test cardiologistsβ prefsβwork that will directly inform future HFrEF polypill clinical trials.
π https://bit.ly/3ZmjsLp
New science π¨!
In an analysis of centrifugal-flow LVAD trials, digoxinπ users showed greater improvement in 6MWT πΆ vs no digoxin (especially in older pts) with similar QOL & AE rates. Digoxin was also linked to better 4-yr survival in NICM pts.
π https://bit.ly/4r5phsy
π£ Last chance to sign up for Office Hours!
Join Editor in Chief Dr. Katz and Deputy Editor Dr. Reza to answer your questions on:
β
JCF-I's upcoming publications
β
What they are looking for in submissions
β
Updates on the year ahead
π Wednesday, January 28th
π 12:00PM - 1:00PM
π bit.ly/3NmOKz4
The January issue of JCF-I is now available π bringing forward new evidence, perspectives, and conversations in heart failure + various intersections.
Read the full issue π https://www.onlinejcfi.org/current
Time is running out! Register for JCF-I Office Hoursβ
Join Editor in Chief Dr. Katz and Deputy Editor Dr. Reza to answer your questions on:
β
JCF-I's upcoming publications
β
What they are looking for in submissions
β
Updates on the year ahead
bit.ly/3NmOKz4
π¨ JCF-I Office Hours
Join Editor in Chief Dr. Katz and Deputy Editor Dr. Reza to answer your questions on:
β
JCF-I's upcoming publications
β
What they are looking for in submissions
β
Updates on the year ahead
π Wednesday, January 28th
π 12:00PM - 1:00PM
Register π: https://bit.ly/3NmOKz4
Overall, meaningful weight loss and potential cardiac benefits.
Read more π bit.ly/3Ka9yZz
π½οΈ Key Highlights
- 125 overweight/obese HF patients Rx LCKD were followed for avg 2 years
- Median weight loss: 11.2 kg (p<0.01)
- No β¬οΈ in EF
- Significant β¬οΈ in HF π₯ in HFpEF, numerically lower in HFrEF
- LCKD was safe, with improvements in several metabolic markers
π’ New study in JCF-I on the safety and effectiveness of a low-carbohydrate ketogenic diet LCKD for weight loss in patients with overweight/obesity and HF.
This is one of the largest real-world looks at LCKD use in HF. π«π½οΈ
See below β¬οΈ
bit.ly/3Ka9yZz
Measuring RVR offers prognostic insight across cardiopulmonary diseases, but definitions and testing methods remain inconsistent.
π Read in Journal of Cardiac Failure β Intersections: bit.ly/3Kdvsef
#HeartFailure #CardioTwitter #PulmonaryHypertension #PeoplesVentricle
How well can the right ventricle rise to the challenge? πͺπ
A new JCF-Intersections paper reviews right ventricular reserve (RVR) β the RVβs ability to boost output under stress. π§΅
Despite higher upfront costs, CABG + OMT emerged as the most cost-effective strategy βguiding smarter care decisions.
Read more: bit.ly/48oKsze
π‘ CABG or PCI? A new perspective on value in ischemic cardiomyopathy.
New #JCFIntersections study on cost-effectiveness analysis comparing CABG + OMT vs PCI + OMT is here.
π Read in Journal of Cardiac Failure β Intersections: bit.ly/48oKsze
#HeartFailure
This is a call to action for hospitals, payers, and policy-makers to close the evidence-to-practice gap.
π Read more: bit.ly/4hyklZR
#HeartFailure #AFib #HealthEquity #QualityImprovement #JCFIntersections #AcademicMedicine
π Key insights: 70% of patients discharged in AF rhythm Underuse of cardioversion, ablation, rehab Large racial disparities in AF/HF prevalence Opportunities for integrated care models.
π Despite increasing evidence for rhythm control and anticoagulation in patients with AF + HF, hospital-level care often falls short of guidelines.
π’ Editorial Spotlight in JCFβIntersections:
βGetting with the Guidelines: Improving Quality of Hospital Care in Atrial Fibrillation and Heart Failureβ by Drs. Ifunanyachukwu Okwuosa, Enat Arega, and Utibe Essien.
bit.ly/4hyklZR
Read more π§΅
π Issue 2 is live! JCF-Intersections continues to explore how collaboration and diversity shape the future of heart failure care.
π‘ Discover more: https://onlinejcfi.org/current
β¨Key editorial JCFβI! βSex Differences in Cardiogenic Shock Supported w/ VA-ECMOβ Highlights:
πΊWomen often present sicker + receive ECMO later
π«Less likely to receive LV venting
βοΈDespite this, survival = comparable to men
πUrgent need to address systemic inequities in shock care
π bit.ly/4hyfXKn
𧬠Editorial highlight in JCF-Intersections: barriers + opportunities for TTR genetic testing in ATTR amyloidosis β‘οΈ Cascade testing + counseling are critical for early diagnosis + family care.
Read here: http://bit.ly/4qqST4h
#CardioTwitter #HeartFailure #Amyloidosis
πNew study explores how πSocial Vulnerability Index (SVI) & Social Deprivation Index (SDI) impact HF hospitalizations.
π₯Counties with higher social vulnerability & deprivation β β¬οΈ HFH rates.
SVI & SDI could help identify vulnerable populations!
πhttps://bit.ly/4omF6di
#AHA2025
ICYMI: Featured in JCF-Intersections inaugural issue:
Post-hoc AFFIRM analysis on association between AAD-based rhythm control and mortality risk in AF + HFpEF, despite improved sinus rhythm.
β‘οΈ Calls for modern trials w/ catheter ablation + GDMT.
π: bit.ly/4hqDvAw
#HeartFailure #AFib #HFpEF
π In JCFβI:
VA-ECMO in cardiogenic shock: are sex differences clinically meaningful?
π©ββοΈ Women had:
β
Less RRT
β
More favorable SAVE scores
π But similar in-hospital mortality to men
This data may inform personalized treatment strategies in mechanical circulatory support.
π bit.ly/4pydpzu
This editorial in JCFβIntersections unpacks a new meta-analysis:
βΆοΈ High-int. CICU staffing = β in-hospital mortality
βΆοΈ Intensivist-led units performed best
βΆοΈ Dual-trained cardiac intensivists=most comprehensive care
What makes the biggest difference in CICU survival?
Staffing. π¨ββοΈπ©ββοΈ
Thomas & Flint call for structured training, better resource allocation, & future-forward triaging systems. π
π bit.ly/4psSrSh
#Cardiology #CICU #CriticalCareCardiology #JCFIntersections
βοΈ Trainee-led pragmatic RCT
βοΈ Embedded in fellowship training
βοΈ Culture of mentorship driving research + careers
π bit.ly/3KpVM4u
#CardioTwitter #HeartFailure #CriticalCare
