Kevan Polkinghorne πŸ‡³πŸ‡Ώ's Avatar

Kevan Polkinghorne πŸ‡³πŸ‡Ώ

@dialysisbloke

#Nephrologist at Monashhealth Prof of Medicine, Monash University #Haemodialysis #BioStats #Epidemiology Melbourne, Australia #MedSky #NephSky #SkyNeph

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07.02.2024
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Latest posts by Kevan Polkinghorne πŸ‡³πŸ‡Ώ @dialysisbloke

Global Medical Staffing

locums nephrology job in north island, new zealand

gmedical.com/job/job-3166...

08.03.2026 23:16 πŸ‘ 12 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

@dialysisbloke.bsky.social
Applied the VIPAR protocol to a patient with cAMR, first time in our centre.
Fingers crossed for positive results 🀞🏻
Just wanted to let you know that it’s being used out there πŸ€“

20.02.2026 08:48 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

Nice. I will let Bill Mulley know. Hopefully goes well for your patient

20.02.2026 10:58 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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βœ… New Clinical Guidance for Kidney Stone Management
Managing kidney stones effectively requires timely decisions and tailored evaluation. This visual summary highlights key steps from acute presentation to post-stone evaluation:

15.12.2025 04:54 πŸ‘ 3 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

I could return to where I had my first job out of medical school….there was no nephrologist there then. I worked for the Gen Physican who looked after the dialysis patients as my first rotation after med school. Must have made an impression

13.12.2025 08:11 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Vol 152, No 23 | Circulation

Delighted to see my Commentary published in the latest issue of #Circulation Journal

Why We Must Rethink Kidney Transplantation as a Cardiovascular Risk–Reducing Intervention in Kidney Failure

Disagree? Happy to be challenged πŸ’ͺ🏼

#StopCardiacTests

Link to issue:
www.ahajournals.org/toc/circ/cur...

08.12.2025 21:08 πŸ‘ 5 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0

Registration now open
url.au.m.mimecastprotect.com/s/ZR0QCNLwzj...

* Causal Inference with Hidden Confounding
* Implementing the Estimand Framework in Clinical Trials
* Pairwise and Network Meta-analysis: Fundamentals and Beyond
* Cluster Randomised Trials: From Fundamentals to State-of-the-Art

04.12.2025 21:09 πŸ‘ 5 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

Stop complaining about pill burden in ESRD!

There is no pill you are giving your dialysis patient that has data half as impressive as this study. If they are taking too many pills have them stop any of the dozen pills they are taking with ZEERO data in ESRD. #NephJC

03.12.2025 02:51 πŸ‘ 27 πŸ” 3 πŸ’¬ 3 πŸ“Œ 0

Correct. Recruitment was super easy. Patients really liked the idea of a natural product.

03.12.2025 05:47 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

A bit late to the party… apologies.

03.12.2025 05:42 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Fish Oil in Dialysis: A Big Catch or an Empty Net β€” NephJC Holy Mackerel! This week we will discuss fish oil use in maintenance hemodialysis patients. Could this be the one thing that bends the curve on CV mortality, or is it just a red herring?

Maybe the most shocking study from #KidneyWk.
🐚From the depths of the oceans to #BlueSky, we're discussing PISCES 🐟 12/2/25 9pm EST. #NephJC
Are you hookedπŸͺon fish oil for CV disease in ESRD, or are you throwing it back 🌊?
www.nephjc.com/news/pisces-fishoil

01.12.2025 18:41 πŸ‘ 20 πŸ” 16 πŸ’¬ 0 πŸ“Œ 3
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The International Vasculitis Workshop is pleased to announce the full speaker lineup for the 2026 event in Melbourne!

Explore the complete list and learn more about each speaker on the Workshop Website: vasculitis-melbourne2026.com/plenary-spea...

28.11.2025 00:12 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The success rate for NHMRC Ideas Grants announced yesterday was just over 8%. That means 11 of every 12 people who applied got rejected. This is a culture changing level of rejection and frankly a point of national shame. This is a crisis for research.
I will not rest until we see this resolved.

26.11.2025 20:33 πŸ‘ 88 πŸ” 32 πŸ’¬ 3 πŸ“Œ 2
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The program for the 22nd International Vasculitis Workshop has now launched!

Filled with amazing plenary speakers and sessions. Visit the website vasculitis-melbourne2026.com/program-full/ and start planning your Workshop!

26.11.2025 02:58 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

No spiro if eGFR<45! How weird

23.11.2025 23:55 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Spent many a holiday there as a young adult. Check out Hahei of possible. A beautiful spot

23.11.2025 05:04 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

A Fantastic band from my home country. All their albums are excellent.

23.11.2025 02:45 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Up next: It might seem a little fishy, but was a great catch 🎣 #NephJC

PISCES, the use of fish oil to decrease mortality in dialysis patients.
www.pubmed.ncbi.nlm....

19.11.2025 02:58 πŸ‘ 6 πŸ” 3 πŸ’¬ 3 πŸ“Œ 0

I have no idea what time this is in Australia. I’ll have to try !

20.11.2025 07:28 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Mark your diaries! The ViCBiostat Summer School returns from 13-20 Feb 2026, in Melbourne and online.
Courses include causal inference, cluster randomised trials, meta-analysis and the estimand framework.
Further details TBA shortly - sign up to our mailing list at www.vicbiostat.org.au
#statistics

12.11.2025 04:09 πŸ‘ 13 πŸ” 10 πŸ’¬ 0 πŸ“Œ 3
JAMA graph: Discordance in Creatinine- and Cystatin C-Based eGFR. Figure 2 shows association of estimated glomerular filtration rate difference with risks of long-term adverse outcomes. Hazard ratio vs. Difference between eGFRcys and eGFRcr, % for Death, CVD death, Heart failure, ASCVD, KFRT.

JAMA graph: Discordance in Creatinine- and Cystatin C-Based eGFR. Figure 2 shows association of estimated glomerular filtration rate difference with risks of long-term adverse outcomes. Hazard ratio vs. Difference between eGFRcys and eGFRcr, % for Death, CVD death, Heart failure, ASCVD, KFRT.

Among more than 800 000 CKD-PC participants, discordance between cystatin C and creatinine eGFR values was associated with increased risk of death, cardiovascular events, and kidney failure.

ja.ma/47A5Gdd

11.11.2025 12:00 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 1
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Final Chance!
Early bird registrations for the International Vasculitis Workshop 2026 close 14 November - and they won’t be extended again.
Register at vasculitis-melbourne2026.com/registration/

11.11.2025 02:21 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

As the Australian PI I have to say I agree. PISCES took 10 years to do as best we could on minimal funding. The result is what it is - we will try to look further in to the data but given the low cost/ low risk what would be the point in doing another larger study? It would be hard to find funding

10.11.2025 08:14 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
JAMA graph shows association of eGFR difference with risks of long-term adverse outcomes. Hazard ratio vs. difference between eGFRcys & eGFRcr (%). Lines for death, CVD death, heart failure, ASCVD, KFRT are plotted. Declining risk as difference approaches zero.

JAMA graph shows association of eGFR difference with risks of long-term adverse outcomes. Hazard ratio vs. difference between eGFRcys & eGFRcr (%). Lines for death, CVD death, heart failure, ASCVD, KFRT are plotted. Declining risk as difference approaches zero.

Among more than 800 000 CKD-PC participants, discordance between cystatin C and creatinine eGFR values was associated with increased risk of death, cardiovascular events, and kidney failure.

#KidneyWK @asnkidney.bsky.social

ja.ma/4oV4DtU

07.11.2025 20:15 πŸ‘ 6 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis | NEJM Cardiovascular disease is the leading cause of death in patients receiving hemodialysis, yet effective preventive therapies remain limited. Supplementation with nβˆ’3 polyunsaturated fatty acids, esp...

In PISCES, daily n–3 fatty acids cut serious cardiovascular events in dialysis patients by nearly half (HR 0.57). Fish oil clearly had bigger fish to fry than placebo: fewer MIs, strokes, cardiac deaths without extra adverse catches

@nejm.org #kidneywk sim publication

www.nejm.org/doi/full/10....

07.11.2025 16:40 πŸ‘ 12 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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Shocking first high impact trial of the day. Fish oil reduces CV events in dialysis patients! #Pisces #kidneywk

Simultaneous pub in NEJM

www.nejm.org/doi/full/10....

07.11.2025 16:44 πŸ‘ 56 πŸ” 16 πŸ’¬ 4 πŸ“Œ 4

Very proud to have lead the Australian arm of PISCES. Huge thanks for Charmaine Lok for the collaboration.

07.11.2025 19:38 πŸ‘ 5 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Recall only a few years ago that the late breaking trials session often has post hoc observation analyses or another negative HD or AKI trial. Indeed it is fantastic. More tomorrow…

07.11.2025 07:52 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Make the most of Melbourne while visiting for the 22nd International Vasculitis Workshop! Explore hidden laneway cafes, explore the coast or unwind in the Royal Botanic Gardens.

Check out the LOC Melbourne Guides: vasculitis-melbourne2026.com/loc-melbourn...

07.11.2025 03:34 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Yes Finerenone okay given the data already out. Plus it will likely get a HF indication by as well. For Atacicept even with the positive slope data one trial in 200 patients won’t cut it I suspect in Australia.

06.11.2025 21:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0