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Wayo Matsushima

@wayomayo

EMBO/JSPS postdoctoral fellow in the Trono lab, EPFL. Studying regulatory evolution driven by transposable elements.

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06.02.2024
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Latest posts by Wayo Matsushima @wayomayo

Very happy to see this work finally published!

I am truly grateful to all the collaborators who made this work possible, especially @ioansarr.bsky.social, @marisepp.bsky.social, and @kaessmannlab.bsky.social. Itโ€™s been a pleasure working with you!

30.01.2026 07:25 ๐Ÿ‘ 15 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Congratulations!!

20.01.2026 13:13 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Blinded by the lights? Re-examining the adaptive role of transposable elements in plants with population genomics Transposable elements (TEs) are ubiquitous components of the genome whose mobility can be triggered by environmental stress and influenced by genotypeโ€ฆ

Have we been overstating the role of transposable elements in adaptation to local or rapidly changing environmental conditions? Happy to share my (somewhat unpopular?) opinion paper on this matter: www.sciencedirect.com/science/arti...
Thanks to those who already shared the link!

05.01.2026 09:02 ๐Ÿ‘ 38 ๐Ÿ” 32 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1

๐ŸšจWe are recruiting two PhD students ๐Ÿšจ

1) Quantitative & dynamic analysis of limb-regenerative signaling centers w/ @osvaldo-chara.bsky.social ๐Ÿ“ถ๐Ÿงฎ๐Ÿ’ป
๐Ÿ”—https://www.phd.tuebingen.mpg.de/80704/Quantitative-and-dynamic-analysis-of-limb-regenerative-signaling-center-interactions

17.12.2025 07:53 ๐Ÿ‘ 8 ๐Ÿ” 12 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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Project Assistant The Department of Medical and Translational Biology at the Faculty of Medicine is now seeking a project assistant for a research project related to human brain aging. The position is full-time and lim

๐Ÿ“ฃWe are looking for a Project Assistant to join my group at the Wallenberg Center for Molecular Medicine at Umeรฅ University. Join us if you are interested in transposable elements, epigenetics and human brain aging. ๐Ÿง ๐Ÿงฌ Dont hesitate to reach out with any questions! ๐Ÿ“ฃ
umu.varbi.com/en/what:job/...

06.12.2025 20:06 ๐Ÿ‘ 8 ๐Ÿ” 10 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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High-quality mouse reference genomes reveal the structural complexity of the murine protein-coding landscape Helmy et al. provide a collection of high-quality mouse reference genomes. They were able to resolve some of the most complex regions among mouse genomes that are involved in immune defense. These fin...

High-quality mouse reference genomes [PacBio Long Read genomes of 17 strains] reveal the structural complexity of the murine protein-coding landscape, Cell Genomics. www.cell.com/cell-genomic... Genomes and annotations here: projects.ensembl.org/mouse_genomes/

02.12.2025 04:30 ๐Ÿ‘ 28 ๐Ÿ” 10 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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๐Ÿ”ฌ Hot #PhD topic: Single-molecule fluorescence and super-resolution microscopy! Use quantitative nanoscale imaging to map nuclear organization. Apply by Jan 7 to join Johannes Steinโ€™s Lab @jmstein.bsky.social & #IMPRS-BAC #gradschool!

๐Ÿ‘‰ www.molgen.mpg.de/5098010/stei...

25.11.2025 14:18 ๐Ÿ‘ 19 ๐Ÿ” 14 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

The IMPRS-BAC is an outstanding PhD program in Europe. And the endogenous retroviruses in development... what can I say? So much exciting biology to uncover! ๐Ÿฆ ๐Ÿงฌ#TEsky #StemCells
Read the instructions and apply! โฌ‡๏ธโฌ‡๏ธโฌ‡๏ธ

28.11.2025 10:00 ๐Ÿ‘ 18 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

๐Ÿชฑ Selfish genes are everywhere and drive some of biologyโ€™s biggest innovations (CRISPR, antibody recombination, epigenetics). Yet almost no one asks the obvious question: how does a selfish gene begin? Our new manuscript uncovers how selfishness can emerge directly from the host genome.

24.11.2025 13:03 ๐Ÿ‘ 61 ๐Ÿ” 38 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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Did transposable elements shape brain evolution โ€” and if so, which ones, and in which cell states and lineages? Led by @tyamadat.bsky.social, we explored this question in cerebellum development using sequence-based deep learning models!
www.biorxiv.org/content/10.1...

16.10.2025 22:01 ๐Ÿ‘ 74 ๐Ÿ” 31 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 1
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It is with great sadness that we share the news of the death of our founder, colleague, mentor and friend, Professor Sir John Gurdon. His vision and dedication will continue to inspire generations of scientists.
๐Ÿ”— www.gurdon.cam.ac.uk/nobel-laurea...

08.10.2025 13:15 ๐Ÿ‘ 68 ๐Ÿ” 25 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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John Gurdon John Gurdon is at the Wellcome Trust/Cancer Research UK Institute of Cancer and Developmental Biology in Cambridge. Educated at Eton and Christ Church, Oxford, he changed from classics to zoology. Dur...

โ€œFor Gurdon to continue in biology would be a complete waste of time both for him and for those who would have to teach himโ€

He proved them wrong! RIP John Gurdon

www.cell.com/current-biol...

07.10.2025 16:21 ๐Ÿ‘ 37 ๐Ÿ” 15 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 2

โšกโšกExcited to announce I'll be starting my lab at the Max Planck Institute of Molecular Genetics (@molgen.mpg.de) in Berlin in December! Leaving sunny California to join a fantastic environment with colleagues who do super cool work.
๐Ÿ”ฌ๐Ÿฆ I'm hiring at all levels! ๐Ÿ”ฌ๐Ÿฆ Check: www.molgen.mpg.de/fueyo-lab

06.10.2025 13:46 ๐Ÿ‘ 86 ๐Ÿ” 26 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 2
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AussiERV 2025 AussiERV: Australiaโ€™s first symposium dedicated to endogenous retroviruses. Join us for this one-day virtual event on November 7th!

Do you research endogenous retroviruses (ERVs) or want to learn more about them? ๐Ÿงฌ๐Ÿค”

Consider presenting at or attending AuusiERV - an inaugural online symposium for ERV research in Australia ๐Ÿ‡ฆ๐Ÿ‡บ (and abroad) ๐Ÿ—บ๏ธ

Abstracts due 1st October!

events.humanitix.com/aussierv-2025

#ERV #retrovirus

27.09.2025 07:28 ๐Ÿ‘ 15 ๐Ÿ” 10 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Cornell University, Molecular Biology & Genetics Job #AJO30607, WDR-00055221 Assistant Professor, Molecular Biology & Genetics, Cornell University, Ithaca, New York, US

๐Ÿ“ฃ Our department is hiring an Assistant Professor in Evolutionary Cell and Molecular Biology to join the @weillinstitute.bsky.social PLS spread the word!
academicjobsonline.org/ajo/jobs/30607

23.09.2025 12:50 ๐Ÿ‘ 53 ๐Ÿ” 59 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 4
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Bioinformatician / Data Scientist (m/f/d) Bioinformatician / Data scientist position in the Aztekin Lab focusing on Structural Regeneration and support the working group together with the other members

๐Ÿš€ Looking for a Bioinformatician / Data Scientist to join our crew and explore regeneration through single-cell genomics & evolutionary biology! @mpi-bio-fml.bsky.social
๐Ÿ“ฉ Questions? Contact us โœ‰๏ธ
๐Ÿ”— Apply here: www.mpg.de/25243280/bio...

15.09.2025 06:58 ๐Ÿ‘ 7 ๐Ÿ” 15 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

I am excited to share that I will join the Friedrich Miescher Institute @fmiscience.bsky.social in Basel as a group leader, starting my lab in March 2026 ๐ŸŽ‰

We will explore cell fate regulation during organogenesis, with a focus on how cell elimination underlies the emergence of functional tissues.

25.08.2025 17:21 ๐Ÿ‘ 159 ๐Ÿ” 24 ๐Ÿ’ฌ 23 ๐Ÿ“Œ 6
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Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...

Finally out! ๐Ÿฅณ Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com ๐Ÿงฌ๐Ÿฆ ๐Ÿ
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5

09.07.2025 10:04 ๐Ÿ‘ 294 ๐Ÿ” 127 ๐Ÿ’ฌ 15 ๐Ÿ“Œ 10
Barbara McClintock portrait

Barbara McClintock portrait

๐Ÿงฌ๐ŸŒฝ Happy Transposon Day! ๐ŸŒฝ๐Ÿงฌ

Today we celebrate the birthday of Barbara McClintock - scientist extraordinaire and discoverer of jumping genes. Still the only woman to have an unshared Nobel Prize in the biomedical sciences #TransposonDay2025

16.06.2025 15:14 ๐Ÿ‘ 479 ๐Ÿ” 192 ๐Ÿ’ฌ 5 ๐Ÿ“Œ 10

Thank you so much!

22.04.2025 11:45 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Come to Lund! We are looking for a postdoc to join the team. #transposons #epigenetics

17.04.2025 12:29 ๐Ÿ‘ 2 ๐Ÿ” 13 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

Huge congrats, Diego!

26.03.2025 14:25 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Thrilled to announce that I am looking for a Research Technician/Assistant to join my lab @imbavienna.bsky.social. Please consider applying if youโ€™re enthusiastic about #devbio #stemcells #teamwork and excited to help shaping a new lab!

Thankful for any retweet! ๐Ÿซถ

imba.onlyfy.jobs/job/l6u2m980

20.03.2025 12:13 ๐Ÿ‘ 50 ๐Ÿ” 42 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 3

Thank you, Miguel! Any feedback is welcome.

10.03.2025 17:14 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Thank you, just updated!๐Ÿ™

10.03.2025 10:26 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Zinc-finger proteins with a co-opted capsid domain anchor nucleosomes over transposon sequences Transposable elements (TEs) are frequently co-opted as cis -regulatory sequences that govern multiple aspects of host biology. The regulatory activity of these domesticated sequences are controlled by...

Sorry broken link. New one here: www.biorxiv.org/content/10.1...

10.03.2025 10:25 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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New preprint of my postdoc work! We found a novel group of zinc-finger proteins that rapidly evolved in a lineage-specific manner to repress regulatory activities of transposon-derived sequences through anchoring nucleosomes. #TEsky

biorxiv.org/content/10.110โ€ฆ

10.03.2025 08:49 ๐Ÿ‘ 33 ๐Ÿ” 10 ๐Ÿ’ฌ 4 ๐Ÿ“Œ 0

Thank you for this fantastic opportunity! Hope youโ€™ll find the elements even stranger after my talk.

03.03.2025 08:52 ๐Ÿ‘ 4 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Very excited to share our paper on Gene and Transposable Element expression in mammalian preimplantation development, online today! www.cell.com/cell/fulltex...
A short thread to highlight some of our findings ๐Ÿงต

20.01.2025 20:29 ๐Ÿ‘ 114 ๐Ÿ” 52 ๐Ÿ’ฌ 7 ๐Ÿ“Œ 5

Huge congrats, Marlies!

20.01.2025 21:32 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0