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Diana Khoromskaia

@dianakhorom

Juniorprofessor @uni-muenster.de Prev: Postdoc @TheCrick @UCL Physics| PhD @WarwickUni| MSc @UniHeidelberg‬ theoretical physics of living matter, cell and tissue morphogenesis

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02.01.2025
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Latest posts by Diana Khoromskaia @dianakhorom

•	Figure 1 of the article: Fig. 1. Phase diagram of tissue material phase transitions and examples. (A) Schematic diagram showing how continuous changes in microscopic dynamics (control parameter) lead to abrupt, drastic, and non-linear shifts in macroscopic properties that define the material response (order parameter). (Aa-Ab) Exemplary phase transitions as traditionally described in non-living matter, e.g. for water (Aa), as well as in living matter, e.g. for embryonic tissues (Ab). Yellow areas indicate fluid-like tissues and regimes. Blue areas indicate solid-like tissues and regimes. Magenta dashed line depicts the critical point. Orange line marks particle and cell trajectories.

• Figure 1 of the article: Fig. 1. Phase diagram of tissue material phase transitions and examples. (A) Schematic diagram showing how continuous changes in microscopic dynamics (control parameter) lead to abrupt, drastic, and non-linear shifts in macroscopic properties that define the material response (order parameter). (Aa-Ab) Exemplary phase transitions as traditionally described in non-living matter, e.g. for water (Aa), as well as in living matter, e.g. for embryonic tissues (Ab). Yellow areas indicate fluid-like tissues and regimes. Blue areas indicate solid-like tissues and regimes. Magenta dashed line depicts the critical point. Orange line marks particle and cell trajectories.

Tissue phase transitions in development: more than just mechanics

In this Review, @nicolettapetridou.bsky.social, @laura-rustarazo.bsky.social and @karengrace12.bsky.social discuss tissue phase transitions during development: doi.org/10.1242/dev....

20.02.2026 13:00 👍 23 🔁 4 💬 0 📌 0

We summarised the many roles of material phase transitions in development (and they are not just mechanical 🤔)

19.02.2026 14:07 👍 31 🔁 9 💬 0 📌 0
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Tissue phase transitions in development: more than just mechanics Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...

Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development!

@karengrace12.bsky.social @nicolettapetridou.bsky.social

🔗 doi.org/10.1242/dev....

19.02.2026 13:31 👍 72 🔁 26 💬 2 📌 2
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New preprint @biorxiv-devbio.bsky.social by Harshath Amal and colleagues from our lab @uni-muenster.de shows how a BMP #morphogen gradient is translated into graded junctional permeability by tuning adhesion and actomyosin contractility in #Drosophila
See tinyurl.com/yhbwd9xh
@sfb1348.bsky.social

18.02.2026 08:43 👍 80 🔁 29 💬 4 📌 1
LinkedIn This link will take you to a page that’s not on LinkedIn

My lab @cri-utsw.bsky.social is looking for a highly motivated postdoct interested in mechanobiology!

We are building a highly collaborative and interdisciplinary team working on how mechanical forces shape immune and cancer cell behavior.

Come do cool science with me!

lnkd.in/gKEXWUGy

13.02.2026 14:46 👍 10 🔁 10 💬 0 📌 0
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Join us today 2-3pm online.

Sign up for the Zoom link here: forms.gle/Mt3y7HQXetrb...

10.02.2026 12:00 👍 2 🔁 1 💬 0 📌 0
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Isasti-Sanchez, J., Münz-Zeise, F., Lancino, M., & Luschnig, S. (2021). Transient opening of tricellular vertices controls paracellular transport through the follicle epithelium during Drosophila oogenesis. Developmental Cell, #EpithelialMechanics doi.org/10.1016/j.de...

16.01.2026 08:01 👍 7 🔁 1 💬 0 📌 0
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Cellular Interfaces reloaded: Join us for the @sfb1348.bsky.social International Meeting on „Mechanochemical signals at cellular interfaces" in Münster from May 27–29, 2026.
Registration opens in February! Limited spots – first come, first serve! More info: tinyurl.com/ypyzd23w
@uni-muenster.de

14.01.2026 14:19 👍 16 🔁 13 💬 0 📌 2
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How does signalling control cortical tension?

Using optogenetics and AFM, we show that myosin recruitment and cortical tension increase proportionally with RhoA signalling.

More here:
www.biorxiv.org/content/10.6...

Super work by Pierre Bohec with Guillaume Salbreux and @dianakhorom.bsky.social

18.12.2025 17:22 👍 55 🔁 11 💬 0 📌 1

New preprint out! We use optogenetics, AFM, and active surface modelling to link signalling ⚡ → mechanics ⚙️ → cell shape 🔵

06.01.2026 13:14 👍 7 🔁 1 💬 0 📌 0

Congratulations, Wolfram!

05.01.2026 12:47 👍 0 🔁 0 💬 1 📌 0
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Looking forward to an exciting @sfb1348.bsky.social seminar with Lucia Baldauf @ucl.ac.uk on January 8, 2026. She will speak about "Illuminating Forces in Living Tissues". More info: www.uni-muenster.de/SFB1348/en/i... Everyone's welcome!

05.01.2026 09:09 👍 8 🔁 4 💬 0 📌 1
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Control of cellular cortical tension and shape by RhoGTPase signalling Shape changes are ubiquitous in biology, from cytokinesis at the single cell scale to tissue-scale morphogenesis involving coordinated changes in hundreds of cells. In all cases, morphogenesis is powe...

www.biorxiv.org/content/10.6...

18.12.2025 11:39 👍 8 🔁 2 💬 0 📌 0

My lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!

18.12.2025 08:36 👍 59 🔁 66 💬 3 📌 2
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🚨 PhD Position Available 🚨
I’m recruiting a PhD student to join my lab at the Multiscale Imaging Centre (MIC), Münster, Germany.

www.bischofflab.com/jobs

Fully funded ✅
#Cellbio #Morphogenesis #Microscopy
#Drosophila #PhD
(Details Below)

Original Posting:
stellen.uni-muenster.de/jobposting/d...

15.12.2025 12:20 👍 44 🔁 36 💬 2 📌 4

Congratulations, Adrien! Exciting news! 👏

12.12.2025 09:24 👍 1 🔁 0 💬 1 📌 0
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#LivingArchitectures
We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay.
www.musee-orsay.fr/fr/agenda/ev...
Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night.
-> Two shows on the 24th and 25th of January.

05.12.2025 16:11 👍 304 🔁 102 💬 19 📌 9
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📢Internships on cellular nematics!

🔬Come for the pretty images, stay for the cool physics: each project combines in vitro experiments with advanced microscopy and image analysis.

📧Feel free to DM or email me with any questions.

02.12.2025 15:15 👍 14 🔁 15 💬 1 📌 0
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02.12.2025 15:41 👍 17 🔁 5 💬 0 📌 0
The historc city center of Münster, famous for the Peace of Westphalia!

The historc city center of Münster, famous for the Peace of Westphalia!

2/2 If you’re into #cellbio, cellular interfaces, #mechanobiology, #membranes, anything related, come to Münster, Germany, May 27–29!

www.uni-muenster.de/SFB1348/en/i...

Please spread the word. It’s a fantastic (and FREE!) meeting. And while you’re here, explore Münster… it’s worth it.

#Science

28.11.2025 08:33 👍 17 🔁 11 💬 0 📌 0
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🧪 Geometry beats chemistry: we show that self-assembly can be controlled by tuning large-scale geometric parameters rather than molecular binding energies.
PNAS: doi.org/10.1073/pnas...
Video summary: www.youtube.com/watch?v=6FS3...
#SelfAssembly #Biophysics #PhysicsOfLife

27.11.2025 16:49 👍 103 🔁 26 💬 5 📌 0
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24 Millionen Euro für zwei Sonderforschungsbereiche Die Deutsche Forschungsgemeinschaft richtet einen neuen Sonderforschungsbereich zur männlichen Unfruchtbarkeit ein und verlängert einen etablierten Verbund zu zellulären Grenzflächen. Insgesamt fließe...

Große Freude! Die @dfg.de richtet einen neuen Sonderforschungsbereich zur männlichen Unfruchtbarkeit ein und verlängert den etablierten Verbund @sfb1348.bsky.social. Insgesamt fließen rund 24 Millionen Euro an die Universität Münster.

21.11.2025 13:44 👍 18 🔁 7 💬 1 📌 3
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Dynamic cellular interfaces reloaded!🎉 Happy and excited to receive extended funding @sfb1348.bsky.social @uni-muenster.de @mpi-muenster.bsky.social and to push our collaborative science forward in the next 4 years! Big thanks @dfg.de, reviewers, and everyone else involved for the continued support!

21.11.2025 11:37 👍 45 🔁 11 💬 5 📌 3

Amazing news, congratulations! 🎉

21.11.2025 11:59 👍 3 🔁 0 💬 1 📌 0
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Physik-Fachgesellschaften unterzeichnen „Erklärung für die Zukunft“ In Münster, der Stadt des Westfälischen Friedens, haben sich die Physikalischen Gesellschaften von Japan und Deutschland im Quantenjahr 2025 mit einer gemeinsamen „Erklärung für die Zukunft“ an die Öf...

In Münster, der Stadt des Westfälischen Friedens, haben sich die Physikalischen Gesellschaften von Japan und Deutschland im Quantenjahr 2025 mit einer „Erklärung für die Zukunft“ an die Öffentlichkeit gewandt. Die Physiker warnen eindringlich vor einer nuklearen Aufrüstung. @dpgphysik.bsky.social

14.11.2025 16:50 👍 7 🔁 5 💬 0 📌 0
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Active nematic pumps | PNAS Microfluidics involves the manipulation of flows at the microscale, typically requiring external power sources to generate pressure gradients. Alte...

Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps.

@pnas.org @ub.edu

www.pnas.org/doi/10.1073/...

#ActiveMatter #Microfluidics #SoftMatter

12.11.2025 19:20 👍 33 🔁 13 💬 2 📌 0
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🚨 Soon at 15:30 EU (in 1h), Guillaume Salbreux (Geneva University) will present the talk

From active surfaces to evo-devo-mechanobiology

at the Population Dynamics Seminars.

sites.google.com/view/popdyn/

14.11.2025 13:36 👍 2 🔁 2 💬 1 📌 0
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Job Alert! The Institute for Neuro- and Behavioural Biology at the Faculty of Biology @uni-muenster.de invites applications for a Full Professorship (W3) in “Systems Neuroscience” - Highly attractive research environment at the Multiscale Imaging Center. Apply by January 5th. See shorturl.at/VczFp

12.11.2025 17:42 👍 27 🔁 34 💬 0 📌 5

Excited to embark on this scientific journey with Ewa Paluch and Daniel StJohnston to understand fundamentals of epithelial tissue and cell shapes! Thank you to @erc.europa.eu for the support!

06.11.2025 12:14 👍 127 🔁 14 💬 24 📌 1
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Mark your calendars! The next SFB 1348 International Meeting will take place in #Münster from May 27-29, 2026, with a focus on #Mechanochemical signals at cellular interfaces. Stay tuned for more details and updates at www.uni-muenster.de/SFB1348/en/m...

27.10.2025 07:00 👍 48 🔁 32 💬 0 📌 3