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Lillemeier lab

@lillemeier-lab

We are a research group at University of Freiburg that studies the molecular mechanisms of T cell activation and how to use them for immunotherapy. https://lillemeier.biologie.uni-freiburg.de/

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24.01.2025
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Latest posts by Lillemeier lab @lillemeier-lab

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"Ex vivo and in vivo CRISPR editing to reprogram T cells" by Dr. Justin Eyquem YouTube video by GLOBAL IMMUNOTALKS

Dr. Justin Eyquem’s seminar entitled “Ex vivo and in vivo CRISPR editing to reprogram T cells” is now available on YouTube: youtube.com/live/tBny7dX...

Please ask questions in the comment section for Justin.
Hope you enjoy it!

11.03.2026 17:19 👍 1 🔁 1 💬 0 📌 0
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INSTALL overcomes fundamental challenges for DNA delivery & integration methods by synergizing immune-stealth nucleic acids with recombinases to enable kb-scale integration strategies w/o viral vectors @nature.com @bkleinstiver.bsky.social @connorjtou.bsky.social
www.nature.com/articles/s41...

11.03.2026 17:46 👍 3 🔁 2 💬 0 📌 0
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Welcome! You are invited to join a webinar: GLOBAL IMMUNOTALKS: Virtual immunology seminar series . After registering, you will receive a confirmation email about joining the webinar. We now offer: ✅ Live streaming on Zoom and YouTube ✅ Live Q&A through Zoom (during live sessions) ✅ Asynchronous Q&A via YouTube comments (after live sessions, contingent to speaker availability) ✅...

Not to be missed! Our next #globalimmuno talk, today Wednesday, March 11th, 2026 at 9am PST, noon EST, 4pm GMT by Dr. Justin Eyquem.

Title: “Ex vivo and in vivo CRISPR editing to reprogram T cells”
ZOOM LINK: us06web.zoom.us/webinar/regi...
LIVE ON YOUTUBE: www.youtube.com/@GLOBALIMMUN...

11.03.2026 14:59 👍 4 🔁 2 💬 0 📌 1
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23 tools to work with (single-cell) TCR/BCR-seq immune repertoire data 🧵 👇

09.03.2026 13:45 👍 5 🔁 1 💬 1 📌 0
Miltenyi Biotec

🧬 Join MACS® Cell Separation Hero Days in Germany: 5 days of hands-on MACS® training, global PhD networking & career workshops.

👉https://www.miltenyibiotec.com/DE-en/lp/macs-cell-separation-hero-days.html

miltenyibiotec.com
MACS Cell Separation Hero Days | Miltenyi Biotec | Deutschland

09.03.2026 13:12 👍 2 🔁 3 💬 1 📌 0
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Do you have a great idea for starting a company? Would you like advice on how to pitch to potential investors? Join us for the EMBO #webinar on 1 April at 16–17:00 CET. 🧪

Register here:
https://embo-org.zoom.us/webinar/register/WN_7SLofSfuTPewgC2VZQVIUw#/registration #startup

09.03.2026 15:05 👍 4 🔁 7 💬 2 📌 0
Microscope and laboratory glassware on a green background with text promoting EU TalentOn, an EU contest for early-career researchers. The visual highlights the event taking place in Brest on 7–11 September 2026 and a prize pool of €80,000, with a call to apply.

Microscope and laboratory glassware on a green background with text promoting EU TalentOn, an EU contest for early-career researchers. The visual highlights the event taking place in Brest on 7–11 September 2026 and a prize pool of €80,000, with a call to apply.

📢 Young researchers (21–35) in Europe, applications for EU TalentOn 2026 are now open.

- Join 100 early-career researchers
- Build market-ready solutions
- Pitch to experts
- Compete for €80 000
- Travel to Brest (fully covered)

Apply by 30 April: eutalentonbrest2026.eu 🧪

09.03.2026 14:54 👍 8 🔁 5 💬 0 📌 0
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PD-1 genetic fate mapping uncovers immune cell diversity mediating the efficacy of combined PD-1 blockade and chemotherapy
www.tandfonline.com/doi/full/10....

08.03.2026 00:27 👍 1 🔁 1 💬 0 📌 0
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Lyn governs the establishment and maintenance of B cell anergy by suppressing PI3K signaling
www.nature.com/articles/s41... @natcomms.nature.com @cuanschutz.bsky.social

08.03.2026 02:44 👍 1 🔁 1 💬 0 📌 1
Preview
Integration of biochemical and physical cues by patrolling CD8+ T cells CD8+ T cell migration is central to host defense, enabling clonal selection, tissue infiltration, and elimination of infected cells. While chemokines guide these cells by activating Rac for F-actin polymerization, recent studies reveal a complementary mechanism through Rho activation. This pathway relies on tissue confinement, which deforms the nucleus, activates the actomyosin network, and allows CD8+ T cells to use physical cues for surveillance without external signals. In this review article, we explore how chemokine- and mechanosensing-dependent pathways guide CD8+ T cell surveillance and introduce a ‘front-’ versus ‘rear-driven’ motility model to illustrate their integration for effective tissue monitoring. Ultimately, the interplay of biochemical and physical cues ensures tissue-specific protection by T cells during homeostasis and inflammation.

Integration of biochemical and physical cues by patrolling CD8+ T cells #immunology

07.03.2026 12:14 👍 4 🔁 3 💬 0 📌 0
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MSCA Postdoctoral Fellowships 2026 MSCA Postdoctoral Fellowships enhance the creative and innovative potential of researchers holding a PhD and who wish to acquire new skills through advanced training, international, interdisciplinary ...

If anyone interested in #postdoc #opportunities in our lab, please let us know. marie-sklodowska-curie-actions.ec.europa.eu/node/1495

07.03.2026 01:41 👍 3 🔁 2 💬 0 📌 0

A post-translational regulatory map of chronic antigen-driven human T cell dysfunction. https://www.biorxiv.org/content/10.64898/2026.03.04.709614v1

07.03.2026 04:19 👍 1 🔁 1 💬 0 📌 0

Kicking off the last session of the symposium, our keynote speaker @mkoehn.bsky.social from
@unibonn.bsky.social spoke about peptide tools used to dissect phosphatase-substrate interactions. Have a look at the human dephosphorylation database (DEPOD) via the link www.depod.org

1/3

#17GPS

06.03.2026 13:16 👍 3 🔁 3 💬 2 📌 0

properly done protein FRET standards that work in cells! Nice work.

06.03.2026 16:47 👍 3 🔁 1 💬 0 📌 0
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Job Alert: The Institute of Integrative Cell Biology & Physiology
@uni-muenster.de is recruiting a lecturer starting 1 July 2026 - permanent, full-time position with 9 SWS teaching. Join a vibrant research and teaching environment in #Münster. Apply by April 15th: tinyurl.com/wn7kesdb

06.03.2026 15:07 👍 5 🔁 6 💬 0 📌 0
Contact/Job - Department of Molecular and Cellular Biology - UNIGE

You are finishing your PhD and looking to continue in science?

The Martin lab @biology-unige.bsky.social has an open postdoctoral position in cell biology to study cell-cell fusion. For more information, please consult mocel.unige.ch/research-gro....

Thanks for reposting!

03.03.2026 09:42 👍 60 🔁 74 💬 1 📌 2

Just sharing this here again! Drop a line if you looking for a long term lab tech job…!

04.03.2026 13:16 👍 2 🔁 4 💬 0 📌 0

Congratulations to our SFB 1381 PI Thomas Ott and his team!

06.03.2026 08:12 👍 7 🔁 1 💬 0 📌 0
Preview
Benchmarking EGF signaling pathway inference using phosphoproteomics and kinase-substrate interactions - Nature Communications To what extent can large-scale approaches accurately reconstruct classic signaling pathways? Here, authors revisit the EGF pathway using phosphoproteomics and kinase-substrate interactions

Is the linear map of cell signaling a myth?
New research suggests the reality of cellular networks is more complex.
@savitski-lab.bsky.social & @saezlab.bsky.social combined experimental and computational expertise to test how we map kinase–substrate interactions.
www.nature.com/articles/s41...

05.03.2026 09:57 👍 10 🔁 4 💬 0 📌 0
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We have three exciting opportunities for you to join us for a fully-funded 4-year #PhD project here in #Manchester starting in October 2026

Find full details of all the projects on our website: www.cruk.manchester.ac.uk/phd-student-...

Applications close 3rd April 2026

05.03.2026 10:25 👍 3 🔁 4 💬 0 📌 0
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Congrats Mary Carrington #NCI @ragoninstitute.bsky.social!
HLA class I signal peptide variation predicts strength of NKG2A+ NK cell response to missing-self and risk of human disease @natimmunol.nature.com
www.nature.com/articles/s41...

04.03.2026 20:35 👍 4 🔁 2 💬 0 📌 0

Have a look at this PhD program in Vienna- most interesting science and the best training program:

03.03.2026 10:18 👍 1 🔁 4 💬 0 📌 0
Laboratory Manager Click the link provided to see the complete job description.

The Mettelman Lab at the University of Pittsburgh Center for Vaccine Research has officially opened its doors, and I’m looking to hire a Lab Manager!

If interested, please apply using the link below

Come join our team of 1!

cfopitt.taleo.net/careersectio...

04.03.2026 21:34 👍 6 🔁 3 💬 0 📌 0
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Lytic IFNγ is stored in cytotoxic granules and coreleased with granzyme B to mediate cytotoxic T lymphocyte killing
www.nature.com/articles/s41...

05.03.2026 03:33 👍 2 🔁 1 💬 0 📌 0
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Postdoc Ad Postdoctoral Position in Computational Phage Biology Microbial Genomics Group, Malopolska Centre of Biotechnology (MCB), Jagiellonian University, Kraków PL Summary We are seeking a postdoctoral rese...

📢 Hiring a Postdoc in Computational Phage Biology (Kraków, Poland)

We study the evolution & structural modularity of prophage-encoded glycan-degrading enzymes in Klebsiella pneumoniae — combining genomics and AlphaFold-based analyses.

Details in attached PDF 👇

26.02.2026 08:44 👍 10 🔁 12 💬 1 📌 0
PhD Student (gn*) Neuro-Immunology PhD Student (gn*) Neuro-Immunology

Join us in Münster to study the immunology of cerebrospinal fluid and the meninges in a human-centric fashion – apply for PhD student position here:
jobs-sf.ukmuenster.de/job/UKM-PhD-...

04.03.2026 12:34 👍 1 🔁 3 💬 0 📌 0
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🚨 #postdoc to be hired in the Paluch Lab 🚨

If you know anyone experienced with and, more importantly, excited about nanoscale architecture of #actincortex and super-res & electron #microscopy do encourage them to apply👇

Amazing colleagues, can only recommend 😉

www.cam.ac.uk/jobs/researc...

03.03.2026 15:50 👍 12 🔁 12 💬 0 📌 0

Spring cleaning in the lab - don’t forget your microscope!

04.03.2026 11:28 👍 1 🔁 1 💬 0 📌 0
Open positions | Neuroimmunology Munich

JOB ALERT 📣 #PhD #position in #autoimmunity and #stroke.
The Kawakami lab in the BMC is seeking a highly motivated #PhD #candidate to investigate how T cells drive inflammation in the central nervous system.

Deadline: 31.03.26
More ➡️ www.neuroimmunology-munich.de/open-positio...

03.03.2026 13:33 👍 0 🔁 1 💬 0 📌 0

New #CIBSS publication from the Jessen Lab!
👇

03.03.2026 07:49 👍 2 🔁 1 💬 0 📌 0