Caroline Weiss

Single-cell spatial proteomics maps human liver zonation patterns and their vulnerability to disruption in tissue architecture - Nature Metabolism Using the single-cell Deep Visual Proteomics technique, the authors develop a resource providing spatially resolved proteomic analysis of individual cells in human liver tissue.

Ever wondered how the human liver looks like at single-cell, spatial protein resolution? We used single-cell Deep Visual Proteomics to map human liver zonation at the protein level - one hepatocyte at a time. Our paper is out in @natmetabolism.nature.com! www.nature.com/articles/s42...

Preprint alert ‼️

Excited to share our work investigating liver zonation in human health and disease with our advanced single-cell Deep Visual Peoteomics framework!

Single cell spatial proteomics maps human liver zonation patterns and their vulnerability to fibrosis https://www.biorxiv.org/content/10.1101/2025.04.13.648568v1