Atomically accurate de novo design of antibodies with RFdiffusion - Nature The combination of computational design, laboratory-based screening and biophysical validation enables the de novo generation of variable heavy-chain antibody fragments and antibodies that precis...

Excited to be a part of this important work. Congrats to everyone involved! www.nature.com/articles/s41...

Really fun collaboration with Roman Melnyk from The Hospital for Sick Children Research Institute and Peter Dosa from University of Minnesota, making synthetic bile acids to be gut-restricted prevents C. difficile infection in a preclinical mouse model