The Holtman Lab 2026 ✨

Lots of new students joining us this year — the group is buzzing with energy, fresh ideas, and inspiration. Excited for what we’ll discover together!

The Holtman lab is blooming in 2025!

Greatly enjoying the Chan Zuckerberg Initiative - Neuroscience meeting in San Jose and developing initiatives for harmonization of Brain Bank neuropathology data using AI. #CZINeuroscience

Spatial mapping of Alzheimer’s disease across genetic subtypes - Nature Genetics Alzheimer’s disease is a complex, heterogeneous disorder with multiple genetic subtypes. Spatial and single-cell gene expression analyses of these subtypes have provided new insights into general and ...

News & Views with @irholtman.bsky.social on spatial and single-cell gene expression analyses of Alzheimer's and Down's Sydrome www.nature.com/articles/s41.... This is a commentary on the work by the Swarup lab: www.nature.com/articles/s41....

Spatial mapping of Alzheimer’s disease across genetic subtypes - Nature Genetics Alzheimer’s disease is a complex, heterogeneous disorder with multiple genetic subtypes. Spatial and single-cell gene expression analyses of these subtypes have provided new insights into general and ...

🚨 New perspectives on Alzheimer’s disease: Spatial transcriptomics is unlocking insights into the cellular and molecular mechanisms. In our News & Views for Nature Genetics we discuss how these approaches reveal shared and subtype-specific pathways for
subtypes of AD. www.nature.com/articles/s41...