MarcelGE_Rommel

A Rare Hematopoietic Stem Cell‐Derived Megakaryocyte Progenitor Accumulates via Enhanced Survival and Contributes to Exacerbated Thrombopoiesis Upon Aging Manso et al. developed strategies for isolating and testing the functional mechanisms regulating age-specific megakaryocyte progenitors derived from hematopoietic stem cells.

Check out the exciting work from Manso, et. al.
onlinelibrary.wiley.com/doi/10.1111/...

Join the New Investigators Committee for their upcoming webinar!

📅 Wednesday, 7 January
🕙 08:00 AM CST
👥 Profs. Elisa Laurenti and David Kent @kentlab.bsky.social

🔗 iseh.org/Webinars-Eve...

Inhibiting ferroptosis enhances ex vivo expansion of human haematopoietic stem cells - Nature Cell Biology della Volpe et al. augment the ex vivo expansion potential of human haematopoietic stem cells (HSCs) by inhibiting ferroptosis with liproxstatin-1 or ferrostatin-1. Treated HSCs have enhanced in vivo ...

🥂Congratulations to @bloodgenes.bsky.social & co for their new study in our journal enhancing the ex vivo expansion and in vivo reconstitution potential of human #hematopoietic #StemCells by inhibiting #ferroptosis . Where? @natcellbio.nature.com ofc!

www.nature.com/articles/s41...

Excited to network, exchange and communicate my experience and research. The trainee conference is unique and special to all trainees and mentors in the stem cell research field 😍 #CIRM #LA #CIRMconference #UCSC #trainee #mentor @cirmnews.bsky.social

Hey #hematopoiesis / #StemCell / #Immunology / #Laboratory people (any field!) Looking for an exceptionally talented and dedicated junior specialist/associate/technician? Have I got the person for you!! They are open to moving anywhere in the US or internationally! DM for details/contact. Please RT!

Mark your calendar! 📅 Join us for the #EUPLAN2025 in Würzburg, Sept 17-19, 2025. A fantastic lineup of speakers in a beautiful city at the heart of Franconian wine region. @benderlab.bsky.social @alessandrabalduini.bsky.social

I'm incredibly grateful for the opportunity to present my work on non-canonical megakaryocytes & platelets during and after IAV infection at the Gordon Research Seminar in Ventura CA. The welcoming and collaborative atmosphere here is truly inspiring! #GRC #GRS #Hematology #scienceCommunity #Ventura

me giving a talk on the spleen modulating systemic platelet activation

Very happy to share our research today at the '25 Gordon Research Seminar on Platelets and Megacaryoctes in Ventura!

Since the new year, I've protected some time to get back in the lab and do science. With all the noise and confusion out there it's a wonderful experience to get focused and make some impactful discoveries again. A great reminder of why we do this.

Senolytics Restore Hematopoietic Stem Cells Function in Sickle Cell Disease Sickle Cell Disease (SCD) is a blood disorder affecting millions worldwide. Emerging evidence reveals that SCD pathophysiology increases risk of myeloid malignancies and hematopoietic stem cell (HSC) ...

Excited to share our work - online today as a preprint. Here, we characterize precocious aging in HSCs of mice and people with sickle cell disease. Excitingly, we demonstrate the potential of senolytics to restore HSC function to the bone marrow of mice with SCD.

www.biorxiv.org/content/10.1...

A kinetics-based model of hematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells Residing at the top of the hematopoietic hierarchy, long-term hematopoietic stem cells (HSCs) are capable of self-renewal and sustained blood cell regeneration. Over the past decades, single-cell and ...

New pre-print from Thomas Höfer, Daniel Hübschmann, @haas_lab and myself, with first authors @Esther_RCorrea @FloGrunschlager and Tamar Nizharadze doi.org/10.1101/2025... @DKFZ @NCT_HD @ChariteBerlin @hi_stem_lab BIH & MDC

Searching for an 'off switch' for cancer Lund University. It was the ability of moose to grow new antlers after shedding that first sparked Nicholas Leigh’s interest in regenerative research. For practical reasons, the choice fell on smaller...

🦎Searching for an "off switch" for #cancer, Nick Leigh and his team at Lund Stem Cell Center study how salamanders regrow limbs and resist cancer. He's also working to make #academia a more inclusive space. @niche-leigh.bsky.social

Read more about Nick's work in & outside the lab:
👉 bit.ly/4h5HPUA