Department of Microbial Pathogenesis

Andrew Goodman Wins Pew Charitable Trust Innovation Fund Award The award, which supports interdisciplinary collaborations, will support Andrew Goodman’s research into how drugs and microbes alter the gut microbiome.

Andrew Goodman Wins Pew Charitable Trust Innovation Fund Award @agoodmanct.bsky.social @yaleschoolofmed.bsky.social #microbiology #pewtrusts m.yale.edu/ddg2

New View of Cholera ‘Tail’ Could Inform Treatment Researchers took a detailed image of the cholera bacteria’s flagella, which could explain how they move so quickly and offer new routes for treatment.

m.yale.edu/dddn @yaleschoolofmed.bsky.social @natmicrobiol.nature.com #flagella #Vibriocholerae

The unique architecture of umbrella toxins permits a two-tiered molecular bet-hedging strategy for interbacterial antagonism Umbrella toxin particles produced by Actinobacteria contain five spokes tipped with variable lectin domains. Here, Zhao et al. show that these lectins mediate species-specific binding to a previously ...

Congratulations to the Mougous Lab @yalemicropath.bsky.social on their discovery of #umbrellatoxins cell.com/cell/fulltex... @cellpress.bsky.social @yalemed.bsky.social

Structural basis of bacteriophage Ur-lambda infection initiation In situ structures reveal molecular insights into infection initiation of bacteriophage Ur-lambda.

Congratulations to #postdoc HuaxinYu in the Liu Lab @yaleschoolofmed.bsky.social for insightful findings @science.org #cryoEM #cryoET #Lambdaphage Structural basis of bacteriophage Ur-lambda infection initiation www.science.org/doi/10.1126/...

Twenty-Seven YSM Faculty Members Recognized for Highly Cited Research Yale School of Medicine faculty members were recognized for publishing studies that rank in the top 1% based on the number of citations they received in their

Congratulations to @agoodmanct.bsky.social @yalemicropath.bsky.social Twenty-Seven YSM Faculty Members Recognized for Highly Cited Research m.yale.edu/dcss #microbiology

Beautiful work using #insitu #cryoEM #SingleParticleAnalysis from @guowangbiao @yalemed.bsky.social in @natmicrobiol.nature.com www.nature.com/articles/s41...

Great work from Jian Yue @yalemicropath.bsky.social @yalemed.bsky.social in @pnas.org #Legionella #T4SS www.pnas.org/doi/10.1073/...

We are so thankful as we congratulate former lab member and outstanding scientist @npokorzynski.bsky.social on his appointment as Assistant Professor of Microbiology @oregonstate.edu #MetabolicReprogramming #proteolysis #antibioticsusceptibility microbiology.oregonstate.edu/directory/ni...

How HIV Uses T Cells to Hide in the Gut Yale researchers identified a transcription factor that creates a perfect haven for HIV to hide. It could be a target for clearing the virus.

@yaleschoolofmed.bsky.social medicine.yale.edu/news-article...

In-situ structures of the Legionella Dot/Icm T4SS identify the DotA-IcmX complex as the gatekeeper for effector translocation The Dot/Icm machine in Legionella pneumophila is one of the most versatile type IV secretion systems (T4SSs), with a remarkable capacity to translocate over 330 different effector proteins across the ...

Exciting findings from the Liu Lab @yalemed.bsky.social and #postdoc Jian Yue, Ph.D. Architecture and activation of the Legionella Dot/Icm type IVB secretion machine #cryoEM #cryoET #Legionella www.biorxiv.org/content/10.1...
medicine.yale.edu/micropath/ne...

@yalegsas.bsky.social Q&A with Michael Grunst #PhD gsas.yale.edu/qa-michael-g... #spikeprotein #microbiology

Mikey Grunst receives 2025 Porter Prize Mikey Grunst, Ph.D. , a recent graduate of the Yale Graduate Program in Microbiology, has been awarded the 2025 John Addison Porter prize.

Congratulations to Mikey Grunst, #PhD! @yalemicropath.bsky.social @yaleschoolofmed.bsky.social medicine.yale.edu/micropath/ne... #spikeprotein #microbiology

Jiaqi Guo Jiaqi Guo is a Postdoctoral Associate at Yale School of Medicine

Congratulations to #postdoc Jiaqi Guo @yalemicropath.bsky.social @yaleschoolofmed.bsky.social on her poster prize at the 10th Annual Biophysics and Structural Biology Symposium #cryoET #cryoFIB #cryoEM medicine.yale.edu/profile/jiaq...

Outer membrane tube formation by Francisella novicida involves extensive envelope modifications and is linked with type VI secretion and alterations to the host phagosomal membrane | mBio Francisella tularensis is an intracellular bacterial pathogen that causes the zoonotic disease tularemia. Following uptake by host cells, the bacteria rapidly escape the phagosome and replicate intracellularly. In previous studies, we found that ...

Congratulations to our #postdoc Shoichi Tachiyama @yalemicropath.bsky.social‬ on his paper @mbio.bsky.social journals.asm.org/doi/10.1128/... #T6SS #cryoET

Ya-Chi Ho promoted to Associate Professor with Tenure Ya-Chi Ho, MD, PhD, has been promoted to Associate Professor with Tenure in the Department of Microbial Pathogenesis at Yale School of Medicine.

medicine.yale.edu/micropath/ne... #HIV #research #microbiology @yaleschoolofmed.bsky.social

FlgY, PflA, and PflB form a spoke–ring network in the high-torque flagellar motor of Helicobacter pylori | PNAS Helicobacter pylori has evolved distinct flagellar motility to colonize the human stomach. Rotation of the H. pylori flagella is driven by one of t...

www.pnas.org/doi/10.1073/... @yalemed.bsky.social @yalemicropath.bsky.social #cryoET

Hualiang Pi receives Searle Scholars award Hualiang Pi, Ph.D., Assistant Professor of Microbial Pathogenesis and member of the Yale Microbial Sciences Institute, receives Searle Scholars grant.

medicine.yale.edu/micropath/ne... #ferrosomes #microbiology @hualiang.bsky.social @yalemed.bsky.social

Infection control: How a pathogen survives a hostile environment A new Yale study reveals the molecular process that helps pathogens thrive in hostile environments — and may offer important insights into antibiotic resistance.

news.yale.edu/2025/04/14/i... #Salmonella @npokorzynski.bsky.social @yalemed.bsky.social

Infection control: How a pathogen survives a hostile environment A new Yale study reveals the molecular process that helps pathogens thrive in hostile environments — and may offer important insights into antibiotic resistance.

news.yale.edu/2025/04/14/i... #Salmonella
@npokorzynski.bsky.social @yalemed.bsky.social

Uchil promoted to Associate Professor Term Pradeep Uchil, PhD, has been promoted to Associate Professor Term in the Department of Microbial Pathogenesis.

medicine.yale.edu/micropath/ne...

Martina Dal Bello receives Human Frontier Science Program award for international collaboration The Yale Microbial Sciences Institute faculty member will collaborate on a microbial science project connecting scholars in three countries

westcampus.yale.edu/news/2025-04...

Eight Yale faculty members named AAAS fellows The American Association for the Advancement of Science has elected eight Yale faculty members as part of its latest class of fellows.

news.yale.edu/2025/03/27/e... #YaleMicroPath @yaleschoolofmed.bsky.social

Rego receives award from Hypothesis Fund Associate Professor Hesper Rego, Ph.D. will receive support from the Hypothesis Fund to investigate the connection between M. tuberculosis metabolism and

Congratulations to Associate Professor Hesper Rego
@yaleschoolofmed.bsky.social on her award from the Hypothesis Fund! #mycobacteria medicine.yale.edu/micropath/ne...

Hidden from sight, bacteria fight for survival in the human gut. Image by Aaron Wexler.

Scientists at the Yale Microbial Sciences Institute reveal a strategy used by microbes to stay ahead in the ‘molecular arms race’ taking place in our gut bit.ly/gut-wars @yaleschoolofmed.bsky.social @yale.edu @cp-cellhostmicrobe.bsky.social