Chrats Melkonian

Really exciting that the preprint on Barbell, a new demultiplexer, is finally out!
It's the first tool that builds on Sassy, the approximate-DNA-searching tool that @rickbitloo.bsky.social and myself developed earlier this year, specifically with this application in mind.

Into natural product biosynthesis & tailoring enzymes? Frustrated by the lack of a dedicated resource to explore their functions? Tired of endless literature searches for reaction info? Meet the MITE database, freely available at mite.bioinformatics.nl. Preprint: doi.org/10.26434/che... (1/8)

Harnessing the phyllosphere microbiota of wild foxtail millet for designing beneficial cross-kingdom synthetic communities Abstract. Understanding the interplay between mechanisms in plant microbiome assembly and functioning of wild ancestors has led to the proposal of a novel

Harnessing the phyllosphere microbiota of wild foxtail millet for designing beneficial cross-kingdom synthetic communities

#ISMEComms by Xiaoyu Zai et al
with @cmelkonian.bsky.social @vivianecordovez.bsky.social @marnixmedema.bsky.social

academic.oup.com/ismecommun/a...

🚨 Open position
We are hiring a PhD student to investigate the ecology and genomics of phyllosphere yeasts combining lab experiments with computational approaches. Joins us at @niooknaw.bsky.social in collaboration with @micropresearch.bsky.social @cmelkonian.bsky.social @marnixmedema.bsky.social

Exciting PhD opportunity with @vivianecordovez.bsky.social : www.linkedin.com/jobs/view/ph...

Excited to be hosting the Paired Omics Mining #community in #Wageningen this week with @marnixmedema.bsky.social! 😎 I hope you are all having safe travels here, and we just brought in some extra good care to make your stay an enjoyable one! 😃

SpeSpeNet: an interactive and user-friendly tool to create and explore microbial correlation networks Abstract. Correlation networks are commonly used to explore microbiome data. In these networks, nodes are taxa and edges represent correlations between the

📣 New, free webtool by the Snoek lab! Meet SpeSpeNet, an intuitive platform for automated network analysis of microbiomes to uncover complex interactions between microbes and their environments

@ismepublications.bsky.social @isme-microbes.bsky.social
doi.org/10.1093/isme...

#microsky #mevosky

It was a pleasure to speak at the Bioinformatics for Food Science Symposium—such an inspiring event! Great discussions and insights on the future of food science.
Thank the organizers @cmelkonian.bsky.social and @marnixmedema.bsky.social for this amazing event!

Justin J.J. van der Hooft on LinkedIn: #bioinformatics #food #sciences #mite #mibig #fermo Looking forward to a great #Bioinformatics in #Food #Sciences symposium today! 😎 Our team will also present on #MITE, #MIBiG, and #FERMO today with Mitja…

www.linkedin.com/posts/jjjvan...

#Bioinformatics #metabolomics #CompMetabolomics

Justin J.J. van der Hooft on LinkedIn: #bioinformatics #food #wageningen Looks indeed quite straightforward to me! 😎 Aschwin Schilperoort from dsm-firmenich presenting today during the #Bioinformatics for #Food Science symposium…

www.linkedin.com/posts/jjjvan...

www.linkedin.com/posts/jjjvan...

With @mmzdouc.bsky.social

Justin J.J. van der Hooft on LinkedIn: #bioinformatics #food Jos Boekhorst making a (significant?!) point during the #Bioinformatics and #Food Sciences symposium at Wageningen University & Research Wageningen Campus

www.linkedin.com/posts/jjjvan...

🚨 Last Call for the Bioinformatics in Food Science Symposium – Feb 24th! 🚨

We are almost at full house, approaching 110 attendees. Fortunately online participation is unlimited!

Register here to receive the meeting link: lnkd.in/dfXTcrCa

#Bioinformatics #FoodScience #Networking #Science

Symposium: Bioinformatics in Food Science Join us to explore how bioinformatics and data science, including AI technologies, are transforming the science behind our food, from microbes in food fermentation and sustainable agriculture to advan...

📢 Abstract Submission Extended Until January 12th.

Don't miss your chance to present at the upcoming Symposium on Bioinformatics in Food Science!

☯️ We encourage abstracts from female speakers. Submit here: forms.gle/nA6b5zx9qv5K...

~80 in-person attendees registered, few spots still available!

Diverse phage communities are maintained stably on a clonal bacterial host Bacteriophages are the most abundant and phylogenetically diverse biological entities on Earth, yet the ecological mechanisms that sustain this extraordinary diversity remain unclear. In this study, w...

Nora finished her paper with a sentence I like a lot "Our results show that even under extremely restrictive, competitive conditions, the simplest biological entities on Earth can still find paths to coexistence." There is a curious dichotomy in her experiments... 1/3
www.science.org/doi/10.1126/...

Some help fixing it would be most welcome.

A new #StarterPack with scientist specialized in microbial bioinformatics - #MicroBioInf.
Please comment if you would like to be added: go.bsky.app/5h7VaGm

Looking forward to the discussions!

Hello, could you please add me, thanks!

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag

Are you working on natural products? We’ve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...

PhD student - Machine learning in bio- and cheminformatics

Here's a first:
I'm hiring a PhD student.
If you have (or know someone who has) a strong background and interest in computational (bio)chemistry or computer science (especially 3D computer vision), let's work together 😊

www.wur.nl/nl/vacature/...

📢 Symposium: Bioinformatics in Food Science. Registrations are now open! Please repost to spread the word.
📅 The symposium is free of charge and will take place at February 24, 2025, at Omnia Auditorium, Wageningen Campus.
💻 Exciting speakers lined up - visit the link for details! lnkd.in/dkzfurdY

Improving genome-scale metabolic models of incomplete genomes with deep learning Microbial genomics; Biocomputational method; Computational bioinformatics; Genomic analysis.

Exciting news! 🎉 My article is out in iScience presenting DNNGIOR, a deep learning tool advancing gap-filling in metabolic models. Huge thanks to co-authors @cmelkonian.bsky.social, @hariszaf.bsky.social, Daniel Garza, Andreas Haas and @bedutilh.bsky.social. Read at shorturl.at/REOm8

Integrating taxonomic signals from MAGs and contigs improves read annotation and taxonomic profiling of metagenomes - Nature Communications Metagenomic taxonomic profiling usually relies either on reads or assembled contigs/MAGs. Here, authors present RAT, a tool that integrates taxonomic signals from reads, contigs, and MAGs into one pro...

The RAT is out! 🐀 Our new Read Annotation Tool integrates taxonomic signals from MAGs, contigs, and reads from #metagenomics 🧬 into one microbial community profile with great sensitivity and precision. Read the article at www.nature.com/articles/s41.... 🧵 (1/5)

Taxonomic resolution of different 16S rRNA variable regions varies strongly across plant-associated bacteria

#ISMEComms by Katarina Hrovat, Bas Dutilh, @marnixmedema.bsky.social and @cmelkonian.bsky.social

academic.oup.com/ismecommun/a...

Standardization of metagenomics is (not) required!
Join the symposium on 2 February in Utrecht: www.knvm.org/activities/6... with @cmelkonian.bsky.social @annecmg.bsky.social @aldertzomer.bsky.social and many more

My first post is a Christmas present to all the cheese lovers and microbiome enthusiast! The key message is that the cheese flavour is not the result of individual microbes alone but of the community. Fantastic teamwork and collaboration between industry and academia. 🎄🎁🧀 rdcu.be/ducw0