Kriti Gupta

Research Associate: Genetic Ageing - DEMENTIA RESEARCHER Exciting opportunity for a Research Associate to explore glial functions in ageing and Alzheimer’s using Drosophila models with Dr Nathan Woodling at Glasgow.

Exciting opportunity for a Research Associate to explore glial functions in ageing and Alzheimer’s using Drosophila models with Dr Nathan Woodling at Glasgow. Closing date: 25th June @nathanwoodling.bsky.social

www.dementiaresearcher.nihr.ac.uk/job/research...

Individual cells within the indicated cell types with the indicated split-GAL4 lines

Why do some neurons say “sleep” while others shout “stay awake!” — inside the same brain?

In fruit flies, researchers just mapped the molecular chaos behind this nightly tug-of-war. And it’s wilder than we thought.
buff.ly/nA9M8EM

Open Positions -

We are recruiting one postdoc and one PhD student to join our lab on #Drosophila #innate immunity in Lausanne (Switzerland). More info: www.epfl.ch/labs/lemaitr...

The 2025 EMBL Annual Poster, listing all of the courses and conferences taking place in 2025 at EMBL

Hi Bluesky community! 👋

Are you looking forward to 2025 as much as we are? 👀

We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look!

➡️ s.embl.org/poster-bl

#EMBLEvents #molecularbiology #lifesciencetraining

Decoding aging clocks: New insights from metabolomics Huang et al. conducted a comprehensive review of the literature on metabolomic aging clocks. They particularly emphasized how metabolomic aging clocks, as a novel tool for quantifying aging, are developed, applied, and interpreted.

Decoding aging clocks: New insights from metabolomics

www.cell.com/cell-metabol...

Synapse profiling of identified neurons in the Drosophila brain https://www.biorxiv.org/content/10.1101/2024.12.02.626511v1

Overlooked histories in ageing research: Pioneering women at the foundation of our field Pioneering women in ageing research. Photo credits: Marjory Warren, Photo: Archives of the British Geriatrics Society; Lillien Martin, courtesy of the Department of Special Collections, Stan...

This Thanksgiving, I am hugely grateful for scientists who were pioneers in our field - particularly those who did not receive the credit they deserved in their own time. Inspiring examples published today:

doi.org/10.1111/acel...

#agingresearch #geroscience #biologyofaging #GeroSky #WomenInSTEM

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Screening for Differentially Expressed Memory Genes on a Diabetes Model Induced by High-Sugar Diet in Drosophila melanogaster: Potential Markers for Memory Deficits - Molecular Neurobiology Type 2 diabetes mellitus (T2DM) has been shown to affect a series of cognitive processes including memory, increasing the risk for dementia, particularly Alzheimer’s disease (AD). Although increasing ...

Loreto, J. S., Ferreira, S. A., ..., Barbosa, N. V. (2024). Screening for Differentially Expressed Memory Genes on a Diabetes Model Induced by High-Sugar Diet in Drosophila : Potential Markers for Memory Deficits. Molecular neurobiology, 61(3):1225-1236 link.springer.com/article/10.1...

Pandey, A., Roy, J. K. (2024). The insc-GAL4 driver marks distinct cell types in #Drosophila midgut. Exp Cell Res, 435(2):113953 www.sciencedirect.com/science/arti...

Our recent study in Cell Metabolism provides compelling evidence that chromatin accessibility and transcription factor network remodeling in aging reflect the predictable degrading effects of a mechanism initially driving organismal maturation.
Link: doi.org/10.1016/j.cmet.2024.06.006
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An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway - Nature Communications Unmet expectations, a previously uncharacterized fly protein, is a SAM sensor for the mTORC1 pathway. Tracing the evolution of Unmet reveals that the pathway uses the GATOR2 complex to capture and rep...

Liu, G. Y., Jouandin, P., Bahng, R. E., Perrimon, N., Sabatini, D. M. (2024). An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway. Nat Commun, 15(1):2517 www.nature.com/articles/s41...

Yes, please.