Mass spec–based spatial omics is evolving fast — optoproteomics pushes it further. Image-guided, light-activated labeling enables proteome profiling in defined subcellular regions, even FFPE tissue.
New review: advancing TME & biomarker discovery.
link.springer.com/article/10.1...
New interview: how Leibniz Institute for Molecular Pharmacology (FMP) is using Microscoop to bring image-guided precision to discovery proteomics.
From synapse subtypes to organelle proteomes, researchers can define ROIs visually and profile them with MS. www.syncell.com/blog/where-d...
Mechanistic biology isn’t just about identifying proteins — it’s about understanding where they function. Our latest blog explores how high-precision targeting within intact cells can refine proteomic discovery and support clearer mechanistic insight.
www.syncell.com/blog/webinar...
What makes some synapses vulnerable — and others resilient — to neuroinflammation?
Join Chun-Wei Chen (UMass Chan Medical School)
🗓March 24 | 1 PM ET
Using Microscoop to uncover neuron-specific programs driving synapse loss in multiple sclerosis. zoom.us/webinar/regi...
Excited to celebrate the installation of a Microscoop system at ONCOCROSS Co., Ltd with Dr. Jong-Bae Park and team.
Dr. Saewhan Park shared:
“David’s training was fantastic! We’re excited to explore LC-MS–based spatial proteomics, uncover subcellular insights, and deliver visually stunning data.”
Syncell collaborated with Thermo Fisher Scientific to develop a poster for the upcoming US HUPO Conference. Presented by Azad, it features a workflow for profiling ciliary proteomes using the Microscoop® platform with the Orbitrap Astral mass spectrometer for precise nanoscale mapping.
Join us at the US HUPO Conference! We’ll present two posters, and our Head of Product Management, will give a lightning talk on overcoming key limits in cell-surface protein profiling. The workflow enables targeted labeling, followed by enrichment, and LC–MS/MS for precise surface proteome analysis.
As we welcome the Year of the Horse, we celebrate speed, strength, and resilience — qualities that fuel discovery and innovation.
At Syncell, we bring that spirit to nanoscopic proteomics, revealing cellular landscapes faster and with greater precision. fore. Happy Lunar New Year! 🐎✨
What if nanoscale protein interactions could reveal new biomarkers and drug targets in the toughest biology?
At the 2026 PBDD Summit, we partnered with Microscoop and Synlight-Pure to present surfaceome advances, showing how 25 nm precision speeds precision medicine in complex biology.
Condensate biology is entering a new era. Our latest blog shows how microscopy-guided protein purification with Syncell’s Microscoop® enables in situ photolabeling at 25 nm precision—unlocking proteomes of nuclear and cytoplasmic condensates across stress and disease.
This February, our team came together for Wěiyá — a traditional Taiwanese year-end feast held according to the lunar calendar to honor employees and teamwork.
We welcomed the new zodiac year with laughter, great food, prizes, live saxophone, singing, and fun activities.
Exciting times at the Max Planck Institute of Biochemistry in Matthias Mann’s lab!
Dr. Mann’s team is exploring subcellular spatial proteomics, combining visual guidance with nanoscale proteomics to study disease-related proteins and key pathways. We look forward to discoveries with #microscoop!
When membrane biology is dynamic and fragile, nanoscale proteomic purification makes a difference.
We will attend the Keystone Symposia on membrane dynamics and autophagy, focusing on shared mechanisms such as ATG8/LC3 conjugation in disease.
At the 2026 Proteomics-Based Drug Discovery Summit in Boston, discover how nanoscale proteomics uncovers new biomarkers and targets—even in challenging biology. Learn how Syncell’s #Microscoop enables high-throughput spatial proteomics with 25 nm precision to accelerate drug development.
Biomolecular condensates are everywhere—but much of their makeup is still a mystery. 🧩
Microscoop uses nanoscopic proteomics for unbiased, in situ profiling, revealing low-abundance proteins and new insights into signaling, cancer & neurodegeneration. 🔬✨
We’re excited to welcome Chris as our Regional Business Leader, Americas 🎉
With 18+ years in life sciences, Chris has built strong technical sales and customer success teams, turning innovation into customer value.
We’re excited to welcome him as Syncell expands across the Americas.
Astrocytes may look similar—but their proteomes differ. 🧠✨
Using Microscoop® Mint, we compared mouse cortex and hippocampus astrocytes, revealing region-specific proteomic signatures.
👉 Watch Matteo Cattaneo explain how spatial proteomics uncovers the invisible.
vimeo.com/1156938415
"Before Microscoop, obtaining a truly specific proteome of a target structure was one of our biggest challenges.” In this customer spotlight, Tolga Soykan from Leibniz Institute Berlin shares how Microscoop® changed his team’s approach to spatial proteomics.
vimeo.com/1153682824/9...
We're headed to #JPM2026 !
Connect with our founder & CEO Jung-Chi Liao and CCO Nikhil Rao to learn how nanoscopic proteomic discovery is changing the biological questions scientists can explore.
#NanoscopicProteomics #Syncell
Syncell is attending the FASEB Phase Transitions in Cellular Signaling and Disease meeting. Connect with us to learn how Microscoop® reveals novel condensate proteomes. Explore applications in stress granules, pTDP-43 aggregates, β-amyloid plaques and more www.syncell.com/dataset/
High-specificity interactome discovery is now achievable with Microscoop. Microscopy-guided photo-biotinylation at 25nm precision enables protein spatial purification from defined subcellular regions, such as to reveal novel microtubule-associated proteins. www.syncell.com/dataset/micr...
From partnering with Thermo Fisher and raising our Series A to launching Synlight-Pure™ with 25 nm precision and expanding globally, we’re proud of Microscoop®’s 2025 momentum and its impact on spatial proteomics.
Here’s to a joyful holiday season and a 2026 full of new insights and breakthroughs.✨
Piping frosting, not pipetting—holiday edition 🎄🧁
Precision doesn’t happen by chance—it starts with the right reagents. 🧪
From photolabeling to protein pull-down, our kits work hand-in-hand with Microscoop® to reveal proteins in stunning detail. Check out our Q&A with Yu-Chun Lee to see the science behind the scenes!
✨ Happy Holidays from the Syncell team!
Time to relax, enjoy the season, and recharge for another year of discovery, creativity, and new adventures. 🎁
By combining microscopy-guided photo-biotinylation with ultra-sensitive mass spectrometry, we identified over 3,000 proteins, including a group of novel proteins, from primary cilia using <15 ng of material.
👉 Dive into the full poster - www.syncell.com/wp-content/u...
Nothing builds team spirit like a good story on the big screen! 🎬✨
The Syncell team took a break from spatial proteomics and headed to the cinema for Movie Day—because even scientists and engineers need popcorn-powered bonding. #Syncell
Using Microscoop®, we performed unbiased microscopy-guided spatial proteomics to label the T and B cell contact site and uncover what’s there. We identified ~3,200 proteins, with 359 enriched at the synapse, including novel putative proteins candidates NDUFA4 and NGDN confirmed by immunofluorescence
Explore tissue biology with hypothesis-free proteomics of submicron structures in FFPE or frozen tissues. Microscoop enables precise spatial proteomics, accelerating biomarker discovery for diagnostics and therapeutics.
🔍 Read the app note on subcellular tissue analysis.
Improving metabolic disease treatment requires deeper insight.
Read the blog on Azad Gucwa’s webinar, highlighting Syncell’s spatial proteomics that maps proteins at subcellular resolution and reveals novel therapeutic targets, including FHL3’s role in lipid metabolism.
buff.ly/WKwNCS3
