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The BanLab

@thebanlab

News from the research group of Prof. Nenad Ban at @ethzurich.bsky.social. The BanLab studies ribosomal protein synthesis in mammals as well as other large cellular assemblies. Group homepage: https://bangroup.ethz.ch

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Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD NAC enables cotranslational N-terminal processing of histones H2A and H4 by recruiting MetAP1 and NatD at the ribosomal tunnel.

Last X-Mas, the ribosome gave you methionine,
but the very next day, MetAP took it away.
This year, to save histones from tears,
NatD gives you an acetyl group. ⭐️

Explore our latest paper with the Deuerling lab @uni-konstanz.de and Shu-ou Chan lab @caltech.edu!

www.science.org/doi/10.1126/...

20.12.2025 00:34 👍 46 🔁 17 💬 0 📌 0
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New paper out in Mol Cell, where we show how N-myristolytransferases lipidate proteins on the translating ribosome!
Continuing our successful collaboration with DeuerlingLab @uni-konstanz.de & Shu-ou Chan @caltech.edu
@snsf.ch @ethz.ch
www.cell.com/molecular-ce...

12.07.2025 00:10 👍 40 🔁 17 💬 0 📌 1