🧬 Episode 12: The New England Journal of IgA?
The team explores the "Hit Zero" hypothesis with Dr. Sparks & Duke Fellow Dr. Ale Tomasi.
- B-Cell Contenders: Sibeprenlimab & Atacicept
- Iptacopan & the Alternative Pathway
The verdict? Tune in! 🏀
Listen: share.transistor.fm/s/b639cd5f
🧪 Episode 11: The C3G Revolution
Hosts @kdjhaveri.bsky.social & Koyal Jain join @nephrosparks.bsky.social & Duke Fellow Dr. Aarushi Varshney to discuss the shifting landscape of C3G.
- The "Two Orders of Magnitude" Rule
- Breaking down APPEAR & VALIANT trials
Listen: share.transistor.fm/s/72477cca
A vibrant, vintage comic book style promotional graphic for the "GN in Ten" podcast, titled "DOUBLE FEATURE SPECTACULAR!" and "NEPHMADNESS SPECIALS!". The image features three medical superheroes: Dr. Kenar Jhaveri as the "IgAN Fighter" holding giant Y-shaped antibody structures, Dr. Jain in a white lab coat holding a defensive shield, and Dr. Sparks in a red cape pointing toward a "Complement Canyon".The layout includes action speech bubbles with "POW!", "BAM!", and "GN!" alongside labels for Episode 11: The C3G Evolution and Episode 12: NephMadness IgA Showdown. A yellow circular call-out box lists the faculty: Hosts Kenar Jhaveri and Koyal Jain, with guests Matt Sparks, Ale Tomasi, and Aarushi Varshney. The International Society of Glomerular Disease logo icon is positioned in the bottom-left corner.
A landscape podcast cover for "GN in Ten," a kidney podcast from the International Society of Glomerular Disease. The background is a blue and purple micrographic kidney scan. The center text reads "Episode 11: NephMadness Special! Matt Sparks and Aarushi Varshney on C3G". At the top, it notes the show is hosted by Dr. Koyal Jain and Dr. Kenar Jhaveri. The bottom-left features the NephMadness 2026 logo, and the bottom-right has a white line-art stopwatch icon.
A landscape podcast cover for "GN in Ten," from the International Society of Glomerular Disease, featuring a blue and purple kidney micrograph background. The text identifies "Episode 12: IgAN (Again?!) With Ale Tomasi and Matt Sparks". The cover lists the hosts as Dr. Koyal Jain and Dr. Kenar Jhaveri. It includes the NephMadness 2026 logo and a white line-art stopwatch icon
💥🎙️ Its a DOUBLE FEATURE: GN in Ten x
@nephmadness.bsky.social
The wait is over. We’re dropping two high-powered episodes to get your brackets ready. Whether you're fighting autoantibodies or the complement cascade, our experts have the breakdown you need! 🦸♂️🦸♀️
@nkf-professionals.bsky.social #ISGD
#NephMadness 2026: The PodCrawl
Featuring these podcasts:
- GN in Ten @isgd.bsky.social
- Global Kidney Care @theisn.org
- @freelyfiltered.bsky.social
- @febrilepodcast.com
- Kidney Commute @nkf-professionals.bsky.social
- @coreimpodcast.bsky.social
- Nephron Segment
bit.ly/NM26Podcrawl
On #RareDiseaseDay & every day, we're uniting a global community to connect, educate, transform, and support GD research and medicine to improve patient care! PS: FDA wants feedback on their rare disease educational materials…more info here eu1.hubs.ly/H0s9nst0
"Expanding brain" meme with 4 levels: Every kidney meeting / all in one place / continuously updated / synced to your own calendar
✈️So many kidney conferences, so little time...Wondering which to attend? Trying to plan a meeting that won't conflict? We have the solution! Our GD Calendar has all the #kidneymeetings info in one subscribable place 📅 You're welcome 😊 www.is-gd.org/calendar-of-...
@tobias-b-huber.bsky.social
10K downloads for #GNin10! 🥳 📈
Congratulations to our hosts @kdjhaveri.bsky.social & Dr. Koyal Jain for their incredible work & dedication to glomerular disease education. 🧬
🎧 Listen here: gninten.transistor.fm
👀 Stay tuned: Special #NephMadness episodes coming early March! 🏀 #NephTwitter #ISGD
Thank you @tobias-b-huber.bsky.social @yelenadrexlermd.bsky.social @alessiafornoni.bsky.social Dr Myda Khalid Dr Shikha Wadhwani Dr Barbara Gillespie Dr Margret Kamel Dr Jennifer McKenzie Dr Scott Wenderfer Dr Zubin J. Modi Dr Neha Pottanat Dr Pamela Winterberg Ashwini Roy-Chaudhury Angel Morales
ISGD Clinical Trial Bootcamp @ the ASPN-PNRC Fellows Workshop! 🩺🔬🌴 We’re bridging the research gap by: ✅ Equipping next-gen investigators ✅ Expanding the trial-ready workforce ✅ Making trials a standard of care
🔗 www.is-gd.org/time-to-trai... #Nephrology #ClinicalTrials #ISGD #PNRC
@utmbpresident.bsky.social @tobias-b-huber.bsky.social
@guptavi.bsky.social
🚀🌴💊 Early Bird Registration and abstract submissions are now OPEN for the 2026 ISGD Clinical Trials Summit in Galveston, TX! Join us in Nov. to advance innovative kidney research, find solutions to glomerular disease challenges, and shape the future of clinical trials. www.is-gd.org/cts-2026-reg...
Meet our Program Advisory Committee 🤩 Excited for what we’ll build together!
Jonathan Barratt
Hiddo Heerspink
Matthias Kretzler
Laura Mariani
Vlado Perkovic
Josh Tarnoff
Marina Vivarelli
Katherine Tuttle
Join our Clinical Trials Summit in Galveston, TX (Nov 13-15 2026) to advance innovative solutions in rare kidney disease trials. Registration & abstracts open Monday! www.is-gd.org/2026-cts @tobias-b-huber.bsky.social @utmbhealth.bsky.social Dr. Shikha Wadhwani
Dr. Jochen Reiser
A blue and purple promotional image for the "GN in Ten" podcast, featuring the International Society of Glomerular Disease logo. The text reads "Board Review Bonus #4: ANCA Vasculitis," and lists hosts Dr. Koyal Jain and Dr. Kenar Jhaveri. A stylized stopwatch icon is in the corner against a background of microscopic cellular structures.
🚨New GN in 10: Everything you need to know about ANCA Vasculitis🎙️
Join @kdjhaveri.bsky.social & Dr. Koyal Jain for a high-yield Board Review session covering all the basics and recent advances: share.transistor.fm/s/8be7fb84
#NephTwitter #MedEd #Vasculitis #BoardPrep @tobias-b-huber.bsky.social
The future of nephrology research is here! 🚀 ISGD Clinical Trial Bootcamps go global in 2026!
📍 Miami, Atlanta, Bordeaux & Mar de Plata.
🎟 Register for PNRC/RPA now: www.is-gd.org/time-to-train
#ISGD #ESPNSociety #PNRC @renalphysicians.bsky.social @alanepe.bsky.social @tobias-b-huber.bsky.social
The International Society of Glomerular Disease is pleased to welcome Barbara Gillespie, MD, MMS, FASN, into the advisory role of Chief Medical and Strategy Officer! 🥳 @tobias-b-huber.bsky.social
www.is-gd.org/en/news-from...
ASN has shown us the incredible advances being made in glomerular diseases and the opportunities we have to continue improving glomerular science, medicine, and patient care! Join the movement at www.is-gd.org/en/join-isgd
#ISGD #GlomerularDisease #ASNKidneyWeek2025 @tobias-b-huber.bsky.social
Post-ASN, the ISGD team visited Galveston and the UTMB campus and team! We chose the venue for the Inaugural 2026 ISGD Clinical Trials Summit. Please save the date: November 12-16, 2026. Stay tuned for more updates on this landmark event! #ClinicalTrials #ISGD @tobias-b-huber.bsky.social
🌐 Building Our Network - Our ASN reception was a massive success, bringing together over 200 people! It is amazing to see the network we have formed in under three years. It was fantastic to connect with so many of you. #ASN2025 #ISGD #KidneyWeek2025 @tobias-b-huber.bsky.social
Congrats to ISGD Members @ksusztak.bsky.social, @rkramann.bsky.social , Laura Mariani, and @genetickidneydoc.bsky.social on receiving major ASN awards! And congratulations to ISGD members who contributed to this year's amazing scientific content 💡#ISGD #KidneyWeek2025 @tobias-b-huber.bsky.social
ISGD had an impactful week at ASN 2025. Big Shout out to Matthias Kretzler ISGD Steering Committee Member and ASN Program Co-Chair, for his leadership in shaping the conference, and for keeping GD at the forefront
#ISGD #ASN2025 #GlomerularDisease #KidneyWeek2025 @tobias-b-huber.bsky.social
Importance of surrogate endpoints - focus on Proteinuria! @ASNKidney
▶️ Proteinuria and Podocyte loss mechanisms 🐙
▶️ Accelerated drug approval 🚀
▶️ A call to Action! by @kirkcampbell - PARASOL results and future expansion 🌟
#KidneyWk #ISGDTweets #GlomerularDisease
Oral Abstract Session 🌟
▶️ The greater the reduction in Proteinuria, the better the outcomes in IgA Nephropathy! 🔑
▶️ Outcomes across diseases and age in the CureGN cohort! 👏
#KidneyWk #ISGDTweets #GlomerularDisease
Outstandining talk by @AstridWeins on anti-nephrin antibodies
▶️ Anti-nephrin Ab provides diagnostic value, guide treatment and define prognosis
▶️ Refined techniques and appropriate treatment-related timing measurement is crucial 🧪
#KidneyWk #ISGDTweets #GlomerularDisease
Innovative initiatives in Pediatric NS!
▶️ PARASOL provides a regulatory path for new drugs by proving proteinuria as a marker 🌟 and is expanding to APOL-1-mediated KD and MN! 🚀
▶️ NEPTUNE Match moving towards personalized medicine 🎯
#KidneyWk #ISGDTweets #GlomerularDisease
Pediatric Nephrotic Syndrome Translational Session
▶️ Diverse Immunological Architecture!
▶️ Recent focus on novel autoantibodies 🎯
▶️ GWAS + composite HLA-PRS in the search of a unified disease mechanism 🧬
#KidneyWk #ISGDTweets #GlomerularDisease
B-cell depleting strategies in lupus nephritis 🐺
▶️ Obinutuzumab confers higher complete remission rates vs other mAbs
▶️ Immunological reset 🆕 CAR-T cells - deeper depletion in varied differentiation stages (for refractory cases!)
#KidneyWk #ISGDtweets #GlomerularDisease
The role of B-cells in lupus nephritis by @AugustoVaglio 🐺
▶️ B-cell activation and expanison
▶️ B-cell overdifferentiation and hiperreactivity
▶️ Isolated germinal centers
#KidneyWk #ISGDtweets #GlomerularDisease
Thrombotic microangiopathy in children - extensive differential @SethiRenalPath!
▶️ From STEC-HUS, TTP to atypical HUS genetics! 🧬
▶️ C3G and DDD involve distinct complement components - ApoE!
▶️ Searching for aHUS specific markers 🔍
#KidneyWk #GlomerularDisease
