#EHA2025

Honoured to have been involved in this study and happy to see it finally published in @bloodjournal.bsky.social. Big Kudos to #DarjaKarpova and #HectorHuerbaEncabo for driving the project 🥇🥇🥇. Read full article here: ashpublications.org/blood/articl...

Congrats 🥂

🙏🙏Thanks🙏🙏@oncodaily.bsky.social and @elisabettabonzano.bsky.social for highlighting our recent paper on #HER3/NRG1 and #FGFR1 signaling in #CTC from #brestcancer patients published in @naturecancer.bsky.social @dkfz.bsky.social

Here the link 👇👇👇👇

rdcu.be/d61IZ

www.uni-heidelberg.de/en/newsroom/...

Interested in understanding how #CTCs colonize distant organs and resist to therapy? Go check the latest paper from #RobertoWürth from #AndreasTrumpp lab on @naturecancer.bsky.social...
🚨SpoilerAlert: we can hijack those mechanisms to establish long term in vitro #CTC derived #organoids

Circulating tumor cell plasticity determines breast cancer therapy resistance via neuregulin 1–HER3 signaling Nature Cancer - Trumpp and colleagues develop a method to obtain long-term circulating tumor cell-derived organoids from individuals with metastatic breast cancer and identify the neuregulin...

Let's start the 2025 with a blast 🎇. Out today on @naturecancer.bsky.social Würth et al., on HER3/NRG1 and FGFR1 compensatory mechanism in CTCs and how to hijack that for long term in vitro culture.
#CTC #breastcancer #liquidbiopsies #NGS #personalizedmedicine @dkfz.bsky.social #HISTEM
rdcu.be/d5pGe

Bioinformatic Postdoc in Cancer Epigenomics

Are you interested in understanding non-genetic therapy resistance mechanisms in cancer? Do you have previous bioinformatic experience with single-cell epigenomic data analysis? Then consider applying to this postdoctoral position in our division:
jobs.dkfz.de/en/jobs/1673...

Join us at FMI as a Junior Group Leader! A unique opportunity to set up your lab in a vibrant international research institute with world-class research groups and facilities, generous core funding, a collegial and inclusive culture - and great colleagues 🤓!

Hello, can you also add me?

Single-cell multiomics analysis reveals dynamic clonal evolution and targetable phenotypes in acute myeloid leukemia with complex karyotype - Nature Genetics An integrated single-cell multiomic analysis of complex karyotype acute myeloid leukemia characterizes intratumoral heterogeneity and highlights links to therapeutic sensitivities.

Extremely proud to see my PhD project exploring intra-tumor heterogeneity in complex karyotype AML finally out in @NatureGenet! 🎉 👩🏻‍🔬

They say that 10,000 hours make you an expert, so I guess after more than five years of work I’m half-way there 😅 ⬇️1/5

www.nature.com/articles/s41...

Congrats Maija 😎🥳