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@chenlabcytokinesis

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25.11.2024
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Latest posts by @chenlabcytokinesis

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Very excited that my final postdoctoral work is now online in Cell @cellpress.bsky.social.

www.sciencedirect.com/science/arti...

Using 16 (!) cryo-EM structures, we uncovered how the three proteins coronin, cofilin and AIP1 work together to rapidly disassemble actin filaments.

13.10.2025 09:04 👍 151 🔁 41 💬 6 📌 5
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First post here, my new review on how #calcium regulates #cytokinesis. It recounts discovery of cytokinetic calcium spikes in #pombe and the force-sensing channel driving such spikes. I compare #yeast to animal cells on calcium transients. Lots of unknown about these mysterious calcium currents.

03.04.2025 17:55 👍 0 🔁 0 💬 0 📌 0

hello, Bluesky! I am a cell biologist. Our lab at the @utoledo.bsky.social studies #cytokinesis using @pombase.bsky.social as the model organism.

03.04.2025 17:38 👍 3 🔁 0 💬 0 📌 0
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The 2nd January issue is live.

www.embopress.org/toc/14693178...

It features work by the lab of Eurico Morais-de-Sá @polarityi3s.bsky.social at IBMC Porto showing that the Dystrophin-Dystroglycan complex ensures #cytokinesis efficiency in #Drosophila #epithelia.

www.embopress.org/doi/full/10....

27.01.2025 13:48 👍 7 🔁 3 💬 0 📌 1
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α-Catenin force-sensitive binding and sequestration of LZTS2 leads to cytokinesis failure This paper shows how epithelial cell–cell junctions play a critical role in the fidelity of cell division, where persistent unfolding of the mechanosensiti

AT LONG LAST… The essential #adherensjunction mechanosensitive protein alpha-catenin is required for #cytokinesis fidelity. We credential a previously defined (but poorly understood) abscission factor in this process, LZTS2. 🧵 1/12 rupress.org/jcb/article-...

10.01.2025 21:19 👍 11 🔁 7 💬 4 📌 1