Our new publication in @cp-immunity.bsky.social: Tertiary lymphoid structures with signs of functional adaptive immune responses in a subset of human gliomas. Association with longer overall patient survival and more immune-permissive tumor microenvironment.
doi.org/10.1016/j.im...
Spatial multi-omics analysis (with COMET) of brains revealed that cells in the TPPB/RT combination treatment group exhibited fewer and shorter TMs, reduced proliferation, increased cell death, and decreased TTYH1 expression (a driver of TM invasion)
#GBM #COMET #Lunaphore @bio-techne.bsky.social
How to disconnect therapy-resistant tumor networks in glioblastoma?
In our paper, online @Cancer Discovery, we built an anti-tumor microtube (TM) screening pipeline and found that Protein Kinase C activators disrupt TMs, silence Ca²⁺ “pacemakers” and boost radiotherapy.
doi.org/10.1158/2159...
Inauguration du COMET Lunaphore au @crcordeliers.bsky.social financé par le @canceropole.bsky.social et les SiRICs @siriccarpem.bsky.social, In Situ, Curamus, Curie
@cancerparisnord.bsky.social
@institpariscarpem.bsky.social
@ap-hp.bsky.social
@inserm.fr
UP Cité
@sorbonne-universite.frm
🚀 Top départ de la journée d’inauguration du Lunaphore COMET sur notre plateforme CHICS
Les bancs sont remplis et une journée qui s'annonce passionnante!
Merci aux financeurs et tutelles
@canceropole.bsky.social @siriccarpem.bsky.social
@inserm.fr @sorbonne-universite.fr @upcite.bsky.social
I'm thrilled to travel to Brisbane this week to meet with multiomics enthusiasts - let's talk #spatial and see how Lunaphore can help accelerate your next discovery #multiomics2024
