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Pierre-Paul Axisa

@ppaxisa

researcher at CBMR (Copenhagen). Genomics, genetics, compbio, biostats, pun lover.

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13.09.2023
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Latest posts by Pierre-Paul Axisa @ppaxisa

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GitHub - EmilHvitfeldt/quarto-revealjs-editable: Repositioning and resizing of images and text directly in quarto revealjs slides Repositioning and resizing of images and text directly in quarto revealjs slides - EmilHvitfeldt/quarto-revealjs-editable

quarto-revealjs-editable has a new release with 5.0.0!!
It is now much more stable, should now work everywhere, plus:

- Rotation support
- Undo/Redo
- Copy qmd to Clipboard
- keyboard controls

github.com/EmilHvitfeld...
#quarto

10.03.2026 17:12 ๐Ÿ‘ 30 ๐Ÿ” 6 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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Issue 35 of #rdmweekly is out!

Including:
โžก๏ธ Building Realistic Fake Datasets with Pointblank @richmeister.bsky.social
โžก๏ธ Rethinking TXT Files @kbriney.bsky.social
โžก๏ธ Economic Benefits of OS @plos.org
โžก๏ธ What Is Data Governance? @thegovlab.org
and more!

Link: rdmweekly.substack.com/p/rdm-weekly...

10.03.2026 13:16 ๐Ÿ‘ 30 ๐Ÿ” 8 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1
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๐Ÿ“ข New preprint out!

tl;dr: Publish your code, add clear README's!

138 participants assessed data & code archiving practices across 1861 papers published at 7 @britishecologicalsociety.org journals, identified gaps & offered recommendations for improvement

๐Ÿ”— doi.org/10.32942/X26...

10.03.2026 08:23 ๐Ÿ‘ 33 ๐Ÿ” 11 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0

"Dashboards" are very frustrating for exactly this reason. Needlessly fancy dashboards look impressive to people who don't use them.

09.03.2026 23:46 ๐Ÿ‘ 11 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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09.03.2026 19:08 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

OpenAI announces ChatGPT is now at the level of real scientific reviewers, โ€œIt just tells you to do single-cell RNAseq in response to every queryโ€ says Sam Altman

09.03.2026 00:58 ๐Ÿ‘ 133 ๐Ÿ” 23 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 1

definitely a problem when dealing with diverse object structures. And you rely on the dev having generated (and documented!) those accessors. I feel like often thereโ€™s an "exotic" slot that was deemed unimportant so you have no choice but to @. S4 feels a bit like "donโ€™t do this at home" to me ๐Ÿ˜…

07.03.2026 16:06 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Seurat versions? ยท Issue #15 ยท LTLA/scRNAseq If I convert the datasets present in this package to Seurat format, with metadata retained between versions, would the authors allow a pull request? I know the community is somewhat split over Sing...

The first time I got familiar with this is this epic rant from Aaron Lun on the Seurat R package to analyse single cell RNAseq data: github.com/LTLA/scRNAse...

07.03.2026 15:06 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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a man in a military uniform is standing in front of a group of people and says `` right to jail '' . ALT: a man in a military uniform is standing in front of a group of people and says `` right to jail '' .

Definitely illegal

07.03.2026 15:05 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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a man with his eyes closed looks at the camera ALT: a man with his eyes closed looks at the camera

And the accessors

07.03.2026 13:46 ๐Ÿ‘ 5 ๐Ÿ” 2 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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a man in a plaid shirt says no no no no wait wait wait wait wait . ALT: a man in a plaid shirt says no no no no wait wait wait wait wait .

S4 methods developers when you type @ to access some slots. #rstats

07.03.2026 13:45 ๐Ÿ‘ 9 ๐Ÿ” 3 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 1

The closure who loved me

07.03.2026 10:16 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Have you looked at the data? Me:

07.03.2026 10:14 ๐Ÿ‘ 4 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
06.03.2026 17:07 ๐Ÿ‘ 62 ๐Ÿ” 10 ๐Ÿ’ฌ 4 ๐Ÿ“Œ 1

I feel like we could collectively come up with some great bond flick names re: #rstats, #GitHub, etc ๐Ÿ˜‚

I submit for your approval: terrible ideas only.

"MIT License to Kill"
"Rebase Another Day"
"The Dev Who Reviewed Me"

06.03.2026 23:35 ๐Ÿ‘ 58 ๐Ÿ” 13 ๐Ÿ’ฌ 34 ๐Ÿ“Œ 11
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Journals and publishers crack down on research from open health data sets PLOS, Frontiers, and others announce policies trying to stem the tide of suspect research

yes - there is certainly an uptick in fairly simple analyses. we've always had a policy excluding simple analyses (BLAST search etc) but what counts as simple is tricky to define and LLMs make a lot of things more simple to do... Others are seeing this too www.science.org/content/arti...

05.03.2026 14:53 ๐Ÿ‘ 2 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

The dilemma is usually: do you want this to be a 2min or a 5 hours conversation?

05.03.2026 13:15 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

A lot of computational biology relies on reusing publicly available data. I guess itโ€™s probably easy to automatically generate a bunch of boiler plate analyses and write a manuscript with LLMs as well. Have you seen an uptick akin to this? Do you think it will be a significant problem?

05.03.2026 13:11 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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a man in a suit and sunglasses is standing in front of a green screen with a skeleton . ALT: a man in a suit and sunglasses is standing in front of a green screen with a skeleton .

Have you considered this:

05.03.2026 09:54 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Write R, ask Claude code to port it to the other language ๐Ÿคช

05.03.2026 09:50 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Then I am biased towards tidyverse, but I think itโ€™s nice to do "here is how you would do it in base R"

05.03.2026 09:47 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

The way I was "brought up" in this: if you have no programming experience, you should not start with R from scratch but take a basic programming course first. I went through the CS50 course, did a bit of bash, python. And I think that was good background to have before diving into R.

05.03.2026 09:44 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

I mean, it's completely fine to say there's a 95% chance that a tibble will not behave as a data frame.

(you can't deny that this was an epic example, incorporating baseR-tidyverse flamewar with frequentist-CI-interpretation-controversial)

04.03.2026 09:46 ๐Ÿ‘ 15 ๐Ÿ” 5 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1

Great to see this work out, led by Jon Rosen and co-supervised Karen Mohlke @klmohlke.bsky.social!

Connecting to some recent threads here:

04.03.2026 16:33 ๐Ÿ‘ 22 ๐Ÿ” 10 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

I wrote something. I hope it can be the start of more conversations about AI and the choices we all have to make.
erincikanek.com/the-rumors-o...

03.03.2026 18:00 ๐Ÿ‘ 28 ๐Ÿ” 9 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 4
A screenshot of two reply messages on bluesky commenting on the same post. The reply on top is very negative about the data.table package, saying 'it was just the worst'. The bottom reply instead claims that data.table's syntax is the best thing produced in #rstats.

A screenshot of two reply messages on bluesky commenting on the same post. The reply on top is very negative about the data.table package, saying 'it was just the worst'. The bottom reply instead claims that data.table's syntax is the best thing produced in #rstats.

Never change #rstats, never change

27.02.2026 17:22 ๐Ÿ‘ 54 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Biological Laboratory | LEGOยฎ Ideas This is a two-floor realistic Biological Laboratory building. In this design, I try to tell stories about biologists, introduce biology concepts to general publโ€ฆ

I just made an account and voted for this biology laboratory made of LEGO to "promote biological research and inspire more people into the world of biology". They need 10K votes. Reposting and/or voting below would be helpful. ๐Ÿค—
beta.ideas.lego.com/product-idea...

16.10.2025 08:07 ๐Ÿ‘ 221 ๐Ÿ” 131 ๐Ÿ’ฌ 8 ๐Ÿ“Œ 12

This is (obviously) a step in the right direction: you should share all the code that led to the results (even if you think there is nothing "new" in your code). But who will review the code sharing?

28.02.2026 21:33 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

> d3.js code with animations, but "vibe coding" scientific apps is likely to be very dangerous. I would need to completely gut this app of the backend stats functions and substitute my own.

28.02.2026 09:22 ๐Ÿ‘ 44 ๐Ÿ” 5 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 0
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a cartoon of two spidermans standing in front of a nypd van ALT: a cartoon of two spidermans standing in front of a nypd van

Also, mandatory spidy meme

27.02.2026 18:54 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0