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Gaston Courtade

@gcourtade

Associate Professor in biopolymer science at NTNU, Trondheim 🇳🇴. Working with CAZymes, NMR and MD simulations. Coordinator for the biotechnology study programs at NTNU. 🔗 https://courtade.folk.ntnu.no/

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27.02.2024
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Latest posts by Gaston Courtade @gcourtade

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Missile strike hits Weizmann Institute of Science lab buildings Extent of damage unclear as conflict between Israel and Iran continues

The Weizmann Institute of Science in Rehovot, Israel, has reported that it was hit during an Iranian air strike on Sunday. cen.acs.org/people/Missi...

18.06.2025 12:57 👍 3 🔁 3 💬 0 📌 1

Not in the EU, but in Oslo you'd be able to call the vaccination center even without being a resident, and get a shot. If you're not in a risk group it would cost you 30 dollars.

22.05.2025 21:00 👍 2 🔁 0 💬 0 📌 0

"I'm fine, just a little tired"

17.05.2025 17:35 👍 1 🔁 0 💬 0 📌 0

I thought that CRYOprobes were able to reach sample temperatures lower than 281.4 K

Smh at "insufficient chiller power"

#NMRchat

13.05.2025 19:00 👍 1 🔁 1 💬 0 📌 0
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PhD Research Fellow in Computational Chemistry (279884) | University of Bergen Job title: PhD Research Fellow in Computational Chemistry (279884), Employer: University of Bergen, Deadline: Sunday, June 1, 2025

PhD position in Bergen on MD+NMR of oligosaccharides with Markus Miettinen, an excellent supervisor. DL: June 1st. www.jobbnorge.no/en/available...

12.05.2025 17:28 👍 2 🔁 4 💬 0 📌 0
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Finally, we're recruiting!
If you'd like to do a PhD using NMR structures to study the dynamics of a metalloenzyme, then you're in luck! Come to Warsaw for this project, in collaboration with Simone Ciofi-Baffoni's group at CERM, Florence: ibb.edu.pl/app/uploads/...

12.05.2025 16:40 👍 11 🔁 8 💬 1 📌 0

Cathartic right? Maybe I should begin using it.

During my PhD we did sing along to "Bad Project" (a cover of Lady Gaga's "Bad Romance").

06.05.2025 04:38 👍 0 🔁 0 💬 0 📌 0

All proteins that don't look like spaghetti.

06.05.2025 04:34 👍 1 🔁 0 💬 1 📌 0
Let It Go - from Frozen (metal cover by Leo Moracchioli)
Let It Go - from Frozen (metal cover by Leo Moracchioli) YouTube video by Frog Leap Studios

youtu.be/so49WpSj9bo?...

05.05.2025 04:32 👍 1 🔁 0 💬 1 📌 0
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This is no way to run a bagel shop or a country Academic science in the US is being gutted by Trump

NSF is in trouble. Here is my latest Substack post. Please share. open.substack.com/pub/artediso...

05.05.2025 01:41 👍 11 🔁 7 💬 1 📌 0
Studier med høy konkurranse om plassene – Samordna opptak april 2025

Data: kfo-hkdir.quarto.pub/samordna-opp...

03.05.2025 17:37 👍 1 🔁 0 💬 0 📌 0
Boblediagram som viser realfagprogrammer i Samordna opptak 2025, der hver boble representerer ett studieprogram.

X-aksen angir antall førstevalgssøkere (fra ca. 5 til 200).

Y-aksen viser antall førstevalgssøkere per studieplass (fra 0,4 til 4,0).

Boblenes størrelse tilsvarer antall studieplasser (store bobler som «Biovitenskap» ved UiO har over 150 plasser, små bobler har under 20).

Fargene koder institusjon (NTNU i mørkeblå, NMBU i lys grønn, UiO, UiB, UiS og UiT i egne farger).

De mest annoterte punktene inkluderer:

«Bioteknologi, Trondheim» (NTNU, ca. 135 søkere, 4,0 søkere/plass),

«Honoursprogram, Realfag» (UiO, ca. 78 søkere, 3,9 søkere/plass),

«Geovitenskap, retning geofysikk» (UiB, ca. 45 søkere, 3,8 søkere/plass),

«Biovitenskap» (UiO, ca. 195 søkere, 1,25 søkere/plass),

«Biologi» (NTNU og UiO, ca. 175 og 125 søkere, hhv. 2,35 og 1,25 søkere/plass).
Diagrammet viser at noen programmer har høy konkurranse (over 3 søkere/plass), mens mange samler moderat interesse (1–2 søkere/plass).

Boblediagram som viser realfagprogrammer i Samordna opptak 2025, der hver boble representerer ett studieprogram. X-aksen angir antall førstevalgssøkere (fra ca. 5 til 200). Y-aksen viser antall førstevalgssøkere per studieplass (fra 0,4 til 4,0). Boblenes størrelse tilsvarer antall studieplasser (store bobler som «Biovitenskap» ved UiO har over 150 plasser, små bobler har under 20). Fargene koder institusjon (NTNU i mørkeblå, NMBU i lys grønn, UiO, UiB, UiS og UiT i egne farger). De mest annoterte punktene inkluderer: «Bioteknologi, Trondheim» (NTNU, ca. 135 søkere, 4,0 søkere/plass), «Honoursprogram, Realfag» (UiO, ca. 78 søkere, 3,9 søkere/plass), «Geovitenskap, retning geofysikk» (UiB, ca. 45 søkere, 3,8 søkere/plass), «Biovitenskap» (UiO, ca. 195 søkere, 1,25 søkere/plass), «Biologi» (NTNU og UiO, ca. 175 og 125 søkere, hhv. 2,35 og 1,25 søkere/plass). Diagrammet viser at noen programmer har høy konkurranse (over 3 søkere/plass), mens mange samler moderat interesse (1–2 søkere/plass).

Happy to see that the 5-year biotech master’s (which we coordinate) tops Norway's 2025 natural sciences programs in applicants-per-spot! It’s great to see that biology & bioscience are popular at other unis too. Thanks to all students & colleagues—looking forward to welcome you to NTNU in August!

03.05.2025 17:36 👍 1 🔁 1 💬 1 📌 0

😳 "This manuscript is an embarrassment to the reader"

(Happened to us)

02.05.2025 19:08 👍 2 🔁 1 💬 0 📌 0

Never have I ever embarrassed reviewer #2.

𝑠𝑘å𝑙! 🍻

29.04.2025 18:16 👍 0 🔁 0 💬 0 📌 0
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PhD Research Fellow in molecular modeling (279265) | University of Bergen Job title: PhD Research Fellow in molecular modeling (279265), Employer: University of Bergen, Deadline: Sunday, May 4, 2025

We have an open PhD position in molecular modeling to work on the recognition of pollutants by fish receptors. More information and application procedure: www.jobbnorge.no/en/available...

Come and work with us ;)

28.04.2025 19:51 👍 5 🔁 7 💬 0 📌 1

Work from Ingrid M. Bolstad's MSc thesis is now a preprint! We show how protein secretion from V. natriegens can be used to screen for PET hydrolases. Also, we include negative results on de novo enzymes generated with RFdiffusion+ProteinMPNN.

03.04.2025 05:18 👍 3 🔁 1 💬 0 📌 0
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TIL that business cards weigh about 80 mg, thanks Microsoft Word.

13.03.2025 11:54 👍 1 🔁 0 💬 0 📌 0

E-flat major, my hero

02.03.2025 08:51 👍 1 🔁 0 💬 0 📌 0

- Very interesting peak shapes, what kind of spectrometer do you have?
- Microsoft Paint

19.02.2025 10:29 👍 3 🔁 0 💬 0 📌 0
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15N-detected TROSY for 1H-15N heteronuclear correlation to study intrinsically disordered proteins: strategies to increase spectral quality - Journal of Biomolecular NMR Intrinsically disordered proteins and protein regions are central to many biological processes but difficult to characterize at atomic resolution. Nuclear magnetic resonance is particularly well-suite...

From CERM, Florence: selective aliphatic 1H decoupling in 15N-detected TROSY experiments results in significant increases in sensitivity and resolution for IDPs

link.springer.com/article/10.1...

18.02.2025 20:20 👍 10 🔁 2 💬 0 📌 1

Me: procrastinating by reading fantasy

George RR Martin:

26.01.2025 11:33 👍 1 🔁 0 💬 0 📌 0
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PhD Candidate in Molecular Modeling (274181) | NTNU - Norwegian University of Science and Technology Job title: PhD Candidate in Molecular Modeling (274181), Employer: NTNU - Norwegian University of Science and Technology, Deadline: Saturday, March 1, 2025

PhD position in molecular modeling at NTNU with Titus S. van Erp. The position is part of the ∞RETIS project, developing algorithms for faster molecular simulations, integrating path sampling simulation techniques with novel parallelization methods. DL: 1st March
www.jobbnorge.no/en/available...

23.01.2025 12:54 👍 3 🔁 0 💬 0 📌 0

After having been inactive for several months, I deactivated my account there today

22.01.2025 13:51 👍 1 🔁 0 💬 0 📌 0
Photo of a cat sitting on a downturned cardboard box.

Photo of a cat sitting on a downturned cardboard box.

I present to you the Catto-Pagnotta barostat. My go-to solution for anisotropic pressure coupling of cardboard boxes.

09.12.2024 16:23 👍 5 🔁 0 💬 0 📌 0
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Determination of the pKa and Concentration of NMR-Invisible Molecules and Sites Using NMR Spectroscopy NMR spectroscopy is a very powerful tool for measuring the dissociation constants (pKa) of molecules, requiring smaller quantities of samples of lower purity relative to potentiometric or conductometr...

Check out the latest from our lab! #NMR #NMRChat

pubs.acs.org/doi/10.1021/...

05.12.2024 12:51 👍 15 🔁 4 💬 0 📌 1
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Perspective: on the importance of extensive, high-quality and reliable deposition of biomolecular NMR data in the age of artificial intelligence - Journal of Biomolecular NMR Artificial intelligence (AI) models are revolutionising scientific data analysis but are reliant on large training data sets. While artificial training data can be used in the context of NMR processin...

Perspective by Higman et al: deposition of data for titrations, relaxation rates, PREs, etc in a standardized way, e.g. the NEF format could help develop AI models to accurately predict the dynamic behaviour of a protein from the primary sequence alone. #NMRchat

doi.org/10.1007/s108...

04.12.2024 10:16 👍 18 🔁 9 💬 0 📌 0
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Yes

02.12.2024 08:25 👍 1 🔁 0 💬 0 📌 0

Ah, no. "Although geldanamycin was active in preclinical studies, it was a poor candidate for clinical trials due to its in vivo toxicity and instability."

26.11.2024 23:38 👍 2 🔁 0 💬 0 📌 0

It looks like geldanamycin binds to Hsp90 with a Kd of ca. 1 µM

26.11.2024 23:13 👍 1 🔁 0 💬 1 📌 0
Futurama-style text saying "Now on Bluesky"

Futurama-style text saying "Now on Bluesky"

Looking forward to catching up with everyone here. You can also see what we're up to on our website: www.ntnu.edu/ibt/courtade...

21.11.2024 14:25 👍 7 🔁 1 💬 0 📌 0