AJR

AI is changing how we approach hard-to-screen diseases. At the AJR Forum on Opportunistic Screening, Michael Rosenthal, MD, PhD shared how AI techniques enable risk enrichment to filter out low-risk individuals and focus efforts on high-risk subgroups.

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The new issue of AJR is now live.

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February 2026: PI-RADS Version 2.1, Automated Protocoling, Canceled Imaging Orders, and More | AJR View all available purchase options and get full access to this article.

The Editor’s Notebook provides readers with highlights of articles in this month’s issue of the yellow journal: PI-RADS version 2.1, automated protocoling, canceled imaging orders, and more. www.ajronline.org/doi/10.2214/...

Scaling Impact With Healthcare Artificial Intelligence—Career Pivots, an AJR Podcast Series (Episode 8) | AJR Summary Curious how radiologists can drive artificial intelligence (AI) change at scale? Ainsley MacLean, MD, speaks with host Siddhant Dogra, MD, about moving from neuroradiology to AI leadership, launching advisory and private equity ventures, deploying AI responsibly, evaluating real-world return on investment, and networking for physicians pursuing innovation, consulting, or investing.

Ainsley MacLean speaks with host Siddhant Dogra about moving from neuroradiology to AI leadership, launching advisory and private equity ventures, deploying AI responsibly, evaluating real-world ROI, as well as networking for physicians. www.ajronline.org/doi/10.2214/...

Increasing Use of Large Language Models for Scholarly Writing in Radiology | AJR View all available purchase options and get full access to this article.

This Research Letter evaluates the surge in LLM usage for scholarly imaging writing following the launch of ChatGPT, comparing trends across medical disciplines to highlight AI's growing role in academic publishing. www.ajronline.org/doi/10.2214/...

This multicenter study reveals that LGE is present in 15.7% of patients with Takotsubo syndrome and is associated with earlier MRI timing and greater edema, providing vital prognostic context for cardiac imaging. www.ajronline.org/doi/10.2214/...

Artificial Intelligence–Assisted Diagnosis of Pulmonary Nodules in Lung Cancer Screening: Counterpoint—False Positives, Workflow Disruption, and the Enduring Role of Radiologists | AJR View all available purchase options and get full access to this article.

While AI promises efficiency in lung cancer screening, this Counterpoint highlights concerns regarding false positives and workflow disruption, emphasizing the enduring necessity of expert radiologist oversight. www.ajronline.org/doi/10.2214/...

Artificial Intelligence-Assisted Diagnosis of Pulmonary Nodules in Lung Cancer Screening: Point—An Evolving Capability That Will Strengthen Screening Practice | AJR View all available purchase options and get full access to this article.

AI-based tools are transforming lung cancer screening by improving consistency and efficiency. This Point explores how these evolving capabilities strengthen screening practice without replacing the radiologist's essential role. www.ajronline.org/doi/10.2214/...

Francesco Ria, PhD, explores the evolution of CT stewardship, emphasizing the successful balance of systematic radiation dose reduction with the preservation of diagnostic integrity to maximize patient value. www.ajronline.org/doi/10.2214/...

Shinn-Huey S. Chou, MD, MPH, highlights promising results from the TMIST lead-in trial, suggesting DBT offers superior screening performance with lower recall and higher cancer detection for women at age extremes. www.ajronline.org/doi/10.2214/...

Minal Jagtiani, MD, and Suraj Serai, PhD, speak with host Raisa Amiruddin, MBBS, on safe, repeatable tracking of pediatric liver iron, fat, and fibrosis with quantitative MRI. ajronline.org/doi/10.2214/...

What It Takes to Architect a 20-Year Career Plan—Radiology Trailblazers, an AJR Podcast Series (Episode 8) | AJR Summary Does your career plan need a reset? Pat Basu, MD, MBA, joins cohosts Lindsey Negrete, MD, and Amy Maduram, MD, to discuss a practical framework for long-term vision, multidisciplinary paths, and executive leadership strategies.

Does your career plan need a reset? Pat Basu, MD, MBA, joins cohosts Lindsey Negrete, MD, and Amy Maduram, MD, to discuss a practical framework for long-term vision, multidisciplinary paths, and executive leadership strategies. www.ajronline.org/doi/10.2214/...

BI-RADS v2025: A Welcome Update | AJR View all available purchase options and get full access to this article.

The ACR BI-RADS v2025 Manual modernizes breast imaging guidelines, harmonizing terminology across modalities to improve diagnostic clarity and reflect contemporary clinical practice. www.ajronline.org/doi/10.2214/...

Incremental Value of Coronary CTA for Predicting First Coronary Events | AJR View all available purchase options and get full access to this article.

Exploring recent findings on coronary CTA, this manuscript highlights its incremental prognostic value in predicting first coronary events beyond traditional risk factors. www.ajronline.org/doi/10.2214/...

MRI-Derived Hepatic Fat Fraction and Stiffness Measurements in Patients With Chronic Liver Disease: A Prospective Comparison Between Vendors and Field Strengths | AJR View all available purchase options and get full access to this article.

A prospective comparison reveals that while MRE stiffness is comparable across MRI platforms, PDFF differences remain significant, necessitating scanner-specific calibration for reliable clinical use. www.ajronline.org/doi/10.2214/...

Preoperative mammographic AI scores are significantly associated with ipsilateral recurrence after DCIS surgery, providing a noninvasive method to guide clinical decision-making and surveillance. www.ajronline.org/doi/10.2214/...

This AJR Review summarizes key milestones and technologic innovations that have led to substantial reductions in CT radiation doses and provides examples of the cumulative impact of these advances on CT doses and image quality.
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This study demonstrates that simple visual coronary calcium scoring on routine PET/CT independently predicts major perioperative events, offering a noninvasive tool to refine surgical risk stratification. www.ajronline.org/doi/10.2214/...

Clarifying the Management of Incidental Pineal Cysts: A Commentary on the New ACR Recommendations | AJR

This commentary discusses recent ACR guidance that provides a practical consensus-based framework for the management of incidental pineal cysts.

www.ajronline.org/doi/10.2214/...

The Investor and Advisor—Career Pivots, an AJR Podcast Series (Episode 7) | AJR Summary A radiologist charts an unconventional path across startups, consulting, and venture capital. Amine Korchi, MD, speaks with host Siddhant Dogra, MD, about radiology training in Switzerland, development of a career advising startups, and leading the wave of innovation as a radiologist.

Amine Korchi, MD, speaks with host Siddhant Dogra, MD, about radiology training in Switzerland, development of a career advising startups, and leading the wave of innovation as a radiologist. www.ajronline.org/doi/10.2214/...

This study explores a modified O-RADS framework incorporating CEUS to aid the diagnosis of borderline ovarian tumors and malignancies.
www.ajronline.org/doi/10.2214/...
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From the Practice Room to the Reading Room: Translating Musical Training to Radiology Practice | AJR View all available purchase options and get full access to this article.

Anisha Mittal, MD, MEd, explores how musical training fosters skills in listening, performance, and discipline that directly translate to excellence in radiology practice and patient communication. www.ajronline.org/doi/10.2214/...

CT Radiation Dose Reduction With Preserved Diagnostic Performance: How Far Have We Come Over 25 Yrs? YouTube video by AJR Radiology

For more, see Dr. McCollough's Author Video:

www.youtube.com/watch?v=H8K3...

A new review finds that advances in CT technology over the past 25 years have enabled routine radiation dose reductions by a factor of 2 to 10, while preserving diagnostic performance when applied appropriately.

www.ajronline.org/doi/10.2214/...

Managing Incidental Findings on Trauma CT | AJR View all available purchase options and get full access to this article.

Experts discuss the management of incidental findings discovered during whole-body trauma CT, addressing the clinical challenges of secondary diagnoses like thyroid and pulmonary nodules. www.ajronline.org/doi/10.2214/...

A new review by Drs. Cynthia McCollough and Lifeng Yu finds that advances in CT technology over the past 25 years have enabled routine radiation dose reductions by a factor of 2 to 10, while preserving diagnostic performance when applied appropriately. arrs.org/ARRSLIVE/Pre...

Evaluating the Cost-Effectiveness of PSMA PET Should Benefit From Additional Research | AJR View all available purchase options and get full access to this article.

This commentary discusses the cost-effectiveness of PSMA PET for prostate cancer, emphasizing the need for real-world evidence to guide therapy development and contain treatment costs. www.ajronline.org/doi/10.2214/...

TMIST Lead-In Randomized Trial of Breast Tomosynthesis Versus Digital Mammography: Results in Women Ineligible for the Full TMIST Trial Due to Age (40–44 or ≥ 74 Years Old) | AJR Background: Digital breast tomosynthesis (DBT) has shown improved screening performance compared to digital mammography (DM), although the modality is less well-studied in women 40-44 or ≥75 years old. Objective: To compare screening performance between DM and DBT in Tomosynthesis Mammographic Imaging Screening Trial (TMIST) Lead-in trial (A4705) participants who were ineligible for transition to the full TMIST trial (EA1151) due to age at trial entry (40-44 or ≥75 years old). Methods: A4705, a prospective trial recruiting women ≥40 years old at four Canadian sites from October 2014 to July /2017, randomized participants to undergo multiple screening rounds by DM or DBT. Final EA1151 eligibility incorporated a narrower age range of 45-74 years. This unplanned analysis included a subset of A4705 participants ineligible for transition to EA1151 due to age at entry (40-44 or ≥75 years old). Examination-level screening performance metrics were calculated. The reference standard was determined by 1-year follow-up after participants' last screening round. Results: The study included 271 A4705 participants (mean age, 54±17 years) age-ineligible for EA1151; 181 were 40-44 years old (76 and 105 randomized to DM and DBT, respectively), and 90 were ≥75 years old (46 and 44 randomized to DM and DBT, respectively). Participants in the DM and DBT arms underwent 389 and 482 screening examinations, respectively (mean, 3.2 screening rounds per participant in each arm). Eight cancers were diagnosed (7 screen-detected [1 by DM; 6 by DBT]; one interval cancer in DBT arm). In participants 40-44 years old, DM, compared with DBT, exhibited recall rate of 13.2% versus 12.0%, cancer detection rate (CDR) per 1000 of 0.0 versus 14.6, PPV1 of 0.0% versus 12.2%, and PPV3 of 0.0% versus 83.3%, respectively. In participants ≥75 years old, DM, compared with DBT, exhibited recall rate of 10.1% versus 3.6%, CDR per 1000 of 7.2 versus 7.1, PPV1 of 7.1% versus 20.0%, and PPV3 of 50.0% in both arms. Conclusion: Screening performance metrics were overall more favorable for DBT than for DM in women 40-44 years or ≥75 years old. Clinical Impact: DBT may mitigate limitations of DM and improve screening performance in the evaluated age groups.

This subanalysis of the TMIST Lead-in trial suggests that digital breast tomosynthesis offers more favorable screening performance than digital mammography for women aged 40–44 or ≥75 years. www.ajronline.org/doi/10.2214/...

Parathyroid Localization: Counterpoint—Targeted Arterial-Phase CT Offers Equivalent Diagnostic Performance With Reduced Dose | AJR View all available purchase options and get full access to this article.

The AJR Counterpoint argues that targeted arterial-phase CT provides equivalent diagnostic performance for parathyroid adenomas compared to multiphase protocols while significantly reducing radiation exposure. www.ajronline.org/doi/10.2214/...