Michela Borghesan

Interview with Adrian Liston

Listen here for an interview I did on "Climbing the Immune Ladder: Steps for Success in Science".

We discuss immunology, kindness and mentorship, navigating scientific challenges, identifying high-impact research questions, and our evolving scientific careers

open.spotify.com/episode/00rJ...

The contest for ERC Public Engagement with Research Award 2026 is officially open! 🎉

This year we have up to 8 prizes of €10,000.

Interested? Submit your application by 15 January 2026.

More info 👉 link.europa.eu/jkX9f4

[Only current or recent ERC grantees can compete]

#ERCengage #SciComm

A small primer on the #NobelPrize awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi today. This prize was for combining two separate fields of immunology research - genetic research on IPEX and immunology research of regulatory T cells (#Tregs), with enormous impact on biology/medicine

Competitiveness through frontier research YouTube video by European Research Council

Tune in TUE 7 Oct 15.00.

High-level event in Copenhagen during #EU2025DK on competitiveness & frontiers science with:

- Minister Christina Egelund
- Nobel laureate Anne L’Huillier
- Breakthrough Prize laureate Sir David Klenerman
- other science leaders

Livestream🎥
www.youtube.com/watch?v=4fLC...

We have a new PhD studentship in the lab on the immunogenic roles of transposable elements in paediatric acute myeloid leukaemia! Come and work with us! www.colcc.ac.uk/2026-cyp-phd...

Macroeconomic income inequality, brain structure and function, and mental health - Nature Mental Health Rakesh et al. used data from the Adolescent Brain Cognitive Development cohort study to evaluate the relationship between state-level income inequality, brain structure and function, and mental health in young people.

www.nature.com/articles/s44...

Are you looking for work in a research group that is led by an ERC grantee? There more than 100 currently open for application on the #Euraxess website 👉 europa.eu/!gdXPfd

#ChooseEurope #jobs #research

Science 101. Correlation does not equal causation. Tylenol aka paracetamol doesn’t cause autism. A correlation can lead to all sorts of causal fallacy. Like so. 👇

Reawakening retrotransposons: immune modulation in normal and malignant hematopoiesis Retrotransposons are mobile repetitive elements that constitute around 43% of the human genome. Normally silenced through epigenetic mechanisms, retrotransposons can become reactivated in response to ...

Our new review is out in Trends in Cancer. We had fund writing this :) We discuss the roles of retrotransposons in immune modulation in normal and malignant
hematopoiesis. www.cell.com/trends/cance...

A systems immunology analysis of Alzheimer’s disease reveals an age- and environmental exposure-independent disturbance in B cell maturation Alzheimer’s disease is a severe neurodegenerative disorder, with multifactorial mechanisms of disease development and progression. Evidence from genetic association studies, animal models, and clinica...

Pre-print time! Our new study on #systemsimmunology analysis of #Alzheimers patients is out now on @medrxivpreprint.bsky.social.

This is the culmination of a long collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8

www.medrxiv.org/content/10.1...

Het is weer @wetenschapwoensdag.bsky.social!

👇🧠👇

#BCN Research School
@rug.nl @umcgroningen.bsky.social
#AcademieMinerva

🧠 Het is weer Wetenschap Op Woensdag!

Volg dit account voor je wekelijkse brein-feit-kunstwerk!
👇

#BCN #ResearchSchool @rug.nl @umcgroningen.bsky.social #AcademieMinerva

Gaat dat zien! Een heel leuke en heel mooi vormgegeven tentoonstelling over de werking van je hersenen.

Very proud of @dangeles.bsky.social. For this preprint he explored the #network structure of depressive symptoms and local brain characteristics of brain regions associated with depression and whether these relate differently in first vs recurrent episode people with major #depression.

Ook ouderen zijn vergroeid met hun smartphone. ‘Mijn schermtijd gister was... 4 uur 48 minuten. Goh’ Jongeren zouden vergroeid zijn met hun smartphone. Maar de oudere generatie kan er ook wat van, blijkt op de camping in Zeewolde. ‘Het is wel ietsje meer dan ik dacht.’

Journaliste Jette Pellemans trok voor @trouw.nl naar de camping om zich te verdiepen in social media- en smartphone-gebruik onder 60+-ers. Ze vroeg mij wat de wetenschap hier over zegt. Een heerlijk artikel voor deze zomerse dag: www.trouw.nl/verdieping/o...

The mechanical anisotropy of adipose tissues regulates ovarian cancer invasion High-grade serous ovarian cancer, the most common and aggressive form of ovarian cancer, generally metastasises to visceral adipose tissues. In these tissues, the extracellular matrix through which ov...

Happy to share our new study on the mechanical regulation of ovarian cancer invasion into adipose tissues! Here we develop adipose tissue-mimicking organo-hydrogels to investigate how cells invade these tissues, a central process in the establishment of metastases! www.biorxiv.org/content/10.1...

Wetenschap op Woensdag Wetenschap op Woensdag

Wekelijks zin in een portie Kunst X Wetenschap? Volg dan vast @wetenschapwoensdag.bsky.social en heb een front row seat wanneer wij ook hier gaan posten!

www.rug.nl/research/beh...

@unigroningen.bsky.social @umcgroningen.bsky.social #AcademieMinerva #BCN #AcademicSky

If neuroscience were a work of art, what would it look like? Minerva Art Academy students teamed up with UG/UMCG brain researchers 🧠🎨

The result? A collection of fascinating art pieces introducing brain research to a broad audience 👇
www.rug.nl/about-ug/lat...

#cancer #spatialbiology #immunohistochemistry #patientsurvival #immunology | ariadne.ai ag Join us for an exciting webinar! 🔬 We’re thrilled to host Ferdinando Pucci, Assistant Professor of Otolaryngology, Cell, Developmental, and Cancer Biology at…

Looking forward to a very interactive session! #spatial #biology #IHC #EVs #extracellularvesicles #Bcells #headneck #cancer
www.linkedin.com/posts/ariadn...

CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks - Nature Communications Cleavage Under Targets & Tagmentation is a rapidly expanding technique, but thorough evaluation and benchmarking against established ChIP-seq datasets are required. This study shows that CUT&T...

We're so thrilled to finally share with you the published version of our CUT&Tag optimization and benchmarking paper "CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks" - out in @naturecomms.bsky.social today: www.nature.com/articles/s41...

Graphical abstract

Thrilled to see our most recent work online at Cancer Research.

aacrjournals.org/cancerres/ar...

In this paper, we elucidate the roles of #extracellularvesicles (#EVs) in #cell #senescence, which is important in the context of tumor #recurrence after #chemotherapy.

flyer of the event with the name of confirmed trainers Cléo Bishop, Eric Boulanger, Manuel Collado and Bill Keyes, Deadline for application May 30th 2025,

I am happy to announce with @hanli-pasteur.bsky.social that we'll organise a summer school titled "Senescence from Cell Cultures to Humans through Model Organisms" in Paris, Fr on June 23-24, 2025
Aimed at 2nd and 3rd year PhD student + postdocs
Submit your provisional project tinyurl.com/2uhfzxbp

Have doctors been wrong about how to treat Alzheimer’s disease? A new book argues that dogma and bad science led Alzheimer’s research astray

'Some chapters read like a scientific whodunnit. In one, Mr Piller has to work hard to earn the trust of a reluctant whistleblower. In another, he travels to Prague for a private meeting with a group of image detectives with cryptic pseudonyms.'
www.economist.com/culture/2025...

archive.ph/bXMr4

An international team led by the NKI discovered how the antibiotic salinomycin can be used against senescent cancer cells. Combined with another drug, it can destroy these cells while activating the immune system.

Read more: bit.ly/3VTA5wL
#precisiononcology

Hello early researchers! Interesting in doing a PhD in senescence, ageing and cancer? We have an open position in our lab in Spain! Please retweet or reach out if interested!

Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.

Immune evasion through mitochondrial transfer in the tumour microenvironmenthttps://

www.nature.com/articles/s41586-024-08439-0

We are hiring! 3-year BBSRC-funded postdoc position available. TEs, epigenetics, pregnancy: if you love one or more of these keywords, apply through the link below.
Please spread the word.

Very exciting paper from Dylan Ryan's lab @ryanlab.bsky.social !! Congrats Dylan & team

Elevated type I interferon responses potentiate metabolic dysfunction, inflammation, and accelerated aging in mtDNA mutator mice IFN-I–NRF2 signaling imbalances drive immunometabolic dysfunction, inflammation, and premature aging in POLG mutator mice.

9/ Our work also adds to the growing evidence of IFN-I involvement in mitochondrial disease, aligning with findings from other models:

🔗 www.biorxiv.org/content/10.1...
🔗 www.science.org/doi/10.1126/...

Thrilled to announce the EHA Research Conference 2025!
Join us for a stellar line-up of talks on: ✨Transcriptional Control and Chromatin Alterations in Normal and Abnormal Hematopoiesis✨
🗓️ Abstract deadline: Jan 8, 2025
📌 Details & personalised flyer below—don’t miss it! ehaweb.org/meetings/eha...