Jamie S Depelteau's Avatar

Jamie S Depelteau

@jamiesd

Structural biologist in Susan Rooijakkers’ group at Utrecht University Medical Center. I use cryo-EM and functional assays to understand bacterial response to the innate immune system. I’m also a husband, daddy, and cook.

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10.09.2023
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Latest posts by Jamie S Depelteau @jamiesd

CryoET of microbes inside an animal organ? Yes it’s possible! Check out our new preprint showing how we did it! What an amazing collaboration with amazing scientists who made this possible!

01.12.2025 04:35 👍 123 🔁 35 💬 2 📌 4

Exciting news for the EM community in the Netherlands!

04.11.2025 10:40 👍 7 🔁 0 💬 0 📌 0
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🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System @xujwet.bsky.social&@chipericson.bsky.social trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal #cryoEM❄️🔬
www.biorxiv.org/content/10.1...

08.10.2025 21:18 👍 62 🔁 30 💬 1 📌 0

ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by Vibrio cholerae www.biorxiv.org/content/10.1101/2025.09.01.673471v1 #cryoEM

02.09.2025 14:15 👍 2 🔁 1 💬 0 📌 0
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Check out 🧐 our new preprint 📜:
www.biorxiv.org/content/10.1...
Congrats🎉 to @vasilgaisin.bsky.social and Corina Hadjicharalambous, who studied contractile injection systems directly in hot spring♨️ bacterial mats🦠
#microsky #teamtomo #Chloroflexota

12.08.2025 07:22 👍 65 🔁 25 💬 3 📌 2
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Scientists crack the case of the melting sea stars. It only took a decade Researchers in Washington and British Columbia say they have solved a deadly mystery that has stumped scientists for more than a decade.

Researchers say they've identified the pathogen behind one of the world’s biggest disease outbreaks: a wasting disease that affected billions of sea stars from Alaska to California. via @kuow.org

04.08.2025 17:41 👍 475 🔁 98 💬 9 📌 14
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Exclusive: Famed protein structure competition nears end as NIH grant money runs out Agency silent on funding renewal for contest that inspired creation of AIs that predicted how proteins would fold

Speak up to prevent a major loss for the field. CASP, which helped shaping structural biology including AlphaFold is on the verge of shutting down. NIH funding has lapsed, UC Davis support ends and the core team is being let go. Painfully shortsighted.

04.07.2025 12:06 👍 64 🔁 46 💬 0 📌 3

I’m sure it filled some amazing science!

20.06.2025 16:05 👍 1 🔁 0 💬 0 📌 0