Cell-to-cell variability and gain of methylation at polycomb CpG islands as a hallmark of aging https://www.biorxiv.org/content/10.64898/2026.03.09.710505v1
Cell-to-cell variability and gain of methylation at polycomb CpG islands as a hallmark of aging https://www.biorxiv.org/content/10.64898/2026.03.09.710505v1
Genome compartments guide protamine replacement and genome stability during spermiogenesis https://www.biorxiv.org/content/10.64898/2026.03.08.710361v1
Bacterial proteome foundation model enhances functional prediction from enzymes to ecological interactions https://www.biorxiv.org/content/10.64898/2026.03.07.710335v1
CollapsedChrom: resolving the assembly of collapsed chromosomal segments in polyploid genomes of the model grass genus Brachypodium https://www.biorxiv.org/content/10.64898/2026.03.07.710290v1
Identification of Dynamic Genetic Influences on DNA Methylation from Birth to Adulthood https://www.biorxiv.org/content/10.64898/2026.03.09.710470v1
Stage-dependent chromatin accessibility remodeling defines an architectural state in facioscapulohumeral muscular dystrophy myoblasts https://www.biorxiv.org/content/10.64898/2026.03.06.710110v1
Breath to genome: Whole genome sequencing of large whales from blow sampling https://www.biorxiv.org/content/10.64898/2026.03.08.710374v1
Biobank-scale genotyping of Robertsonian translocations reveals hidden structural variation on the human acrocentric chromosomes https://www.biorxiv.org/content/10.64898/2026.03.08.710242v1
Chromosome-level genome assembly and annotation of the parthenogenetic nematode Acrobeloides nanus https://www.biorxiv.org/content/10.64898/2026.03.06.710095v1
Performance of the 10X Genomics Flex Single-Cell Sequencing Assay and its Application to Overcome Challenges in Clinical Trial Samples https://www.biorxiv.org/content/10.64898/2026.03.06.710062v1
A family portrait of the genomic factors shaping tandem repeat mutagenesis https://www.biorxiv.org/content/10.64898/2026.03.06.710071v1
Exercise induces Skeletal Muscle Methylome and Transcriptome changes, regardless of Age and COPD https://www.biorxiv.org/content/10.64898/2026.03.06.710054v1
The complete genome of the KOLF2.1J reference iPSC line https://www.biorxiv.org/content/10.64898/2026.03.06.710144v1
Significantly Improved Mouse and Rat Genome Annotation Using Sequence Read Archive RNA-seq Data https://www.biorxiv.org/content/10.64898/2026.03.06.709975v1
Side-necked turtle genomes reveal chromosomal dynamics, skeletal innovation and cancer resistance https://www.biorxiv.org/content/10.64898/2026.03.05.709825v1
Integrative analysis reveals extensive interactions among C2H2 zinc finger proteins at chromatin loop anchors https://www.biorxiv.org/content/10.64898/2026.03.06.710197v1
The relationship between genomic variation and genetic load: insights from small island populations https://www.biorxiv.org/content/10.64898/2026.03.06.710193v1
The complete chloroplast genome of Garcinia binucao (Blanco) Choisy, an indigenous fruit from the Philippines https://www.biorxiv.org/content/10.64898/2026.03.04.709719v1
Reprogramming of neuronal genome function and phenotype by astrocytes https://www.biorxiv.org/content/10.64898/2026.03.07.710282v1
A Translocation within the Ogataea Species Complex Alters Local Subtelomeric Chromatin while Maintaining Overall Genome Organization https://www.biorxiv.org/content/10.64898/2026.03.05.709876v1
Fixative eXchange (FX)-seq: Scalable Single-nucleus RNA Sequencing Analysis of PFA-fixed or FFPE Tissue https://www.biorxiv.org/content/10.64898/2026.03.05.709668v1
Single-molecule spatial genomics reveals the multi-scale organization and plasticity of extrachromosomal DNA in glioblastoma https://www.biorxiv.org/content/10.64898/2026.03.05.709911v1
Diversity and Genomic Organization of Non-B DNA Motifs in Haplotype-Resolved Human Genome Assemblies https://www.biorxiv.org/content/10.64898/2026.03.05.709836v1
Alternative 3' Polyadenylation Responses to Acute Ethanol Exposure Differ Between Drosophila Populations https://www.biorxiv.org/content/10.64898/2026.03.05.709877v1
Exploring genetic, expression and regulatory patterns of parental alleles in Muscovy duck (Cairina moschata) using haplotype-resolved assemblies https://www.biorxiv.org/content/10.64898/2026.03.04.709678v1
Popformer: Learning general signatures of positive selection with a self-supervised transformer https://www.biorxiv.org/content/10.64898/2026.03.06.710163v1
MERFISH 2.0, an ultra-sensitive single-cell spatial transcriptomics imaging chemistry across diverse tissue types https://www.biorxiv.org/content/10.64898/2026.03.06.710199v1
A chromosome-level reference genome for the colonial marine hydrozoan Podocoryna americana https://www.biorxiv.org/content/10.64898/2026.03.04.709628v1
Evolutionary emergence and preservation of microproteins encoded by upstream ORFs https://www.biorxiv.org/content/10.64898/2026.03.05.709866v1
Evolutionary instability drives structural diversity and disease susceptibility at the 16p12.2 locus https://www.biorxiv.org/content/10.64898/2026.03.04.709583v1