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George Goodwin

@gg9761

Research Fellow, King's College London Studying the neurobiological mechanisms of arthritis pain

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03.07.2025
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Latest posts by George Goodwin @gg9761

@arthritisaction.org.uk @arthritisuk.bsky.social @wolfsonsparc.bsky.social @kingsioppn.bsky.social #PPI #Arthritispain #painresearch

03.03.2026 14:56 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Microsoft Forms

🦴 Living with arthritis pain?

We’re starting a new project on arthritis pain and want to learn from your experience.

πŸ‘‰ Which movements trigger or worsen your pain?

Please take a few minutes to complete our short survey:
forms.office.com/e/qv0tx9LJ1L

Your input will help guide our research.

03.03.2026 14:03 πŸ‘ 2 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

I'm hiring!

I am seeking a research assistant to support my fellowship research on arthritis pain. You'll join me in the fun, friendly and collaborative @wolfsonsparc.bsky.social

πŸ‘‰More details here: www.kcl.ac.uk/jobs/137085-...

⏰Closing date is 22nd February.
#painresearch #pain

29.01.2026 15:41 πŸ‘ 7 πŸ” 6 πŸ’¬ 0 πŸ“Œ 0
Cartoon transparent human with skeleton showing, red glowing points on joints to indicate pain

Cartoon transparent human with skeleton showing, red glowing points on joints to indicate pain

Do YOU live with joint pain?

Do YOU experience poor pain management?

Have you got 2-minutes to tell pain researchers about it?

If yes πŸ‘‰ forms.gle/7NTwma2gnVN1...

We hope to gain insight into lived experience for those with joint pain & involve people in our #PainResearch πŸ˜ƒ

20.12.2025 09:57 πŸ‘ 11 πŸ” 12 πŸ’¬ 0 πŸ“Œ 0

Looking forward to reading this!! Painless NGF seems to have moved away from p75 and onto TrkA biased signaling. www.biorxiv.org/content/10.1...

18.11.2025 21:47 πŸ‘ 6 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Preview
Loss of peptidergic innervation of the subchondral bone in a murine model of MIA-induced osteoarthritis In the present study, we aimed to determine how osteoarthritis (OA) affects the morphology and distribution of nociceptive nerve endings in the subcho…

www.sciencedirect.com/science/arti...
Great paper from Jason Ivanusic’s lab: they imaged CGRP fibres in cleared joints and found a major loss of subchondral bone innervation in MIA vs controlsβ€”opposite to the idea of NGF-driven sprouting in OA. Does the MIA just wipe out the fibres?

10.10.2025 09:02 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Please feel free to contact Stuart or me for further details

06.10.2025 09:13 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The GIF shows GCaMP6s-labelled sensory neurons exhibiting spontaneous activity (visible as flickering) in a model of pain.

06.10.2025 09:13 πŸ‘ 2 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
Video thumbnail

Stuart Bevan and I are offering an exciting MRC DTP-funded PhD project exploring the mechanisms of pain in Long COVID.

Find out more about the project here:
πŸ”— tinyurl.com/3caseacv

Application deadline: 28th October

@wolfsonsparc.bsky.social y.social
@kingsioppn.bsky.social sioppn.bsky.social

06.10.2025 09:09 πŸ‘ 8 πŸ” 6 πŸ’¬ 1 πŸ“Œ 0

So good to see you former colleague πŸ˜†. Great talk as per usual. I hope to see you in Copenhagen soon!

07.09.2025 17:30 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Great session, thanks for organising and nice to meet you.

05.09.2025 07:44 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Preview
NKG2D receptor ligands are cell surface biomarkers for injured murine and human nociceptive sensory neurons Nociceptors are primary afferent neurons that sense noxious stimuli. They can be activated by tissue injury as well as the accompanying local immune response. We have shown that following nerve injury...

Neuronal subtype-specific expression of NKG2D ligands, injury models, and axonal degeneration? We have a new preprint @ndcnoxford.bsky.social
www.biorxiv.org/content/10.1...

21.07.2025 13:52 πŸ‘ 8 πŸ” 3 πŸ’¬ 1 πŸ“Œ 2
Claude Jay - Love Is The Answer (12" Club Mix 1986)
Claude Jay - Love Is The Answer (12" Club Mix 1986) YouTube video by Coolfunk ZΓ©zΓ© 2

youtu.be/Y5AW3dtoIR4?...
And a tune to go with it!

11.07.2025 13:36 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

β€œLove is the answer”
#fluorescentfriday

8β€―Β΅m longitudinal section of the Stellate Ganglion. Neurons expressing tdTomato (red). I love this oneβ€”these sympathetic neurons innervate the heart, and the section even resembles a heart emoji ❀️

11.07.2025 12:08 πŸ‘ 6 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

Hello Bluesky.
Thrilled to finally share some exciting news: I’ve been awarded a 5-year Career Development Fellowship from @versusarthritis.bsky.social to investigate the role of silent nociceptors in arthritis pain.
More info below in the PR.

10.07.2025 10:07 πŸ‘ 8 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

#PainResearch
Great PostDoc opportunity from Mat πŸ₯³

08.07.2025 06:26 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Psilocybin has no immediate or persistent analgesic effect in acute and chronic mouse pain models The psychedelic psilocybin may have lasting therapeutic effects for patients with chronic pain syndromes. Some clinical and preclinical data suggest these putative benefits derive from direct analgesic effects. However, this possibility has not been comprehensively tested in preclinical models. Here, we show that psilocybin is not analgesic over a range of doses across multiple pain assays and models of acute and chronic inflammatory, neuropathic, or musculoskeletal pain in mice. ### Competing Interest Statement B.D.H. is on the scientific advisory boards of Journey Clinical and Osmind, and is a paid consultant to Arcadia Medicine, Inc, Tactogen, LLC, and Vida Ventures, LLC. R.C.M. is now on leave from Stanford, functioning as Chief Scientific Officer at Bayshore Global Management. R.C.M. is on the scientific advisory boards of MapLight Therapeutics, Bright Minds, MindMed, and Aelis Farma. International Anesthesia Research Society, https://ror.org/0252rqe04, Mentored Research Award National Institute on Drug Abuse, T32DA035165, P50DA042012

www.biorxiv.org/content/10.1...

08.07.2025 12:11 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Fabulous teamwork with @taamslab.bsky.social! Our findings provide a mechanistic explanation for why JAK inhibitors are better painkillers in #arthritis πŸ§ͺ🧠 #PainResearch #PainScience #Immunosky

23.06.2025 18:47 πŸ‘ 6 πŸ” 2 πŸ’¬ 2 πŸ“Œ 0