Great response to our correspondence to Clarice Leung and John Fahy on the association between FeNO and baseline membrane thickness in SARP-3. This seems like a good marker of type-2 inflammation, and more specifically IL-13 activity, in #asthma.
www.atsjournals.org/doi/abs/10.1...
📰 For #WorldAsthmaDay check out this #OpenAccess meta-analysis on inflammatory and clinical risk factors for #asthma attacks (ORACLE2)
Findings support incorporation of blood eosinophils and FeNO into clinical risk stratification
🔗 tinyurl.com/93ar3am3
@simcouillard.bsky.social
"Mepolizumab to Prevent Exacerbations of COPD with an Eosinophilic Phenotype."
Publié ce jour dans le @nejm.org.
#MedSky @simcouillard.bsky.social
www.nejm.org/doi/full/10....
A bar chart showing the change from baseline in forced vital capacity at week 52 in the overall trial population
In the FIBRONEER-IPF phase 3 trial, nerandomilast slowed disease progression in patients with idiopathic pulmonary fibrosis as compared with placebo. Full trial results: nej.md/4mgWcIU
#ATS2025 @atscommunity.bsky.social
🧵A new COPD diagnostic schema that includes chest imaging, respiratory symptoms, and spirometry identified more high-risk individuals and excluded low-risk ones. #ATS2025
ja.ma/4dp9i30
Hey #ATS2025, help us spread the word on our revolutionary person-centered framework on supplemental oxygen to improve wellbeing & independence for patients & families.
jamanetwork.com/journals/jam...
@pallipulm.bsky.social
@atscommunity.bsky.social
@jamainternalmed.com
@angelasuen.bsky.social
Lung art installation
So grateful for the community and science (and 🫁 art!) at #ATS2025
A JAMA study examines a multidimensional diagnostic approach for #COPD that uses a new diagnostic schema for more individualized and inclusive COPD patient care. #ATS2025
ja.ma/3GYcUg1
Congrats to our teaching competition representative Dr. Chris Chou for winning the #ATS2025 teaching competition ✍️with his novel approach to explaining chest tube mechanics! 🫁
@ats-assemblies.bsky.social
1/ The amazing UW PCCM fellows are headed to #ATS2025! 🤩
In these challenging times, their commitment to research and improving patient care gives me hope.
@atscommunity.bsky.social
@atsearlycareer.bsky.social
@apccmpd.bsky.social
🚨 Funded Clinical Research Fellowship
Asthma/COPD focus | MSc/PhD req | 2–3 yrs | 80% research, 20% clinic | Sherbrooke, QC 🇨🇦
French is a must (95% francophone patients).
📩 S.Couillard@USherbrooke.ca
🌐 DM for details!
www.usherbrooke.ca/dep-medecine...
🚨 Our new paper is out in The Lancet Respiratory Medicine!
ORACLE2 pooled 6,500+ #asthma patients from 22 RCTs.
🧪 Blood #eosinophils + #FeNO = key predictors of #asthma attacks
💨 Reversibility = lower risk?
Open access: www.thelancet.com/journals/lan...
#asthma #ORACLE2
🚨 New paper in @lancetrespirmed.bsky.social !
ORACLE2: we pooled data from 6,500+ asthma patients x22 RCTs.
🧪 Blood eosinophils + FeNO = powerful predictors of asthma attacks (esp. together)
💨 Surprise: more lung reversibility = lower risk?
Open access 👉 doi.org/10.1016/S221...
Global collab 💪
🚀 Exciting News! 🚀 Thrilled to share that our paper, Phenotyping the Responses to Systemic Corticosteroids in the Management of Asthma Attacks (PRISMA), has been accepted for publication in the European Respiratory Society ERJ journal! 🎉 Congratulations to 1st author @pulmonology101.bsky.social
Phenotyping Responses to Systemic Corticosteroids in the Management of #Asthma Attacks (PRISMA). Blood #eosinophils and #FeNO can stratify asthma #exacerbations, predicting better clinical responses to #OCS. @simcouillard.bsky.social @usherbrooke.bsky.social
publications.ersnet.org/content/erj/...
Apprenez en davantage sur notre projet Propulsion Santé 👉. Merci FMSQ pour le beau résumé et la visibilité. Merci AstraZeneca, Opération-Enfant-Soleil , et Association pulmonaire du Québec pour le financement ayant permis de partir un projet qui se déploie maintenant à vitesse grand V. 🚀
Honored to step into the role of Director of the Public Health Institute at Javeriana University in Bogotá.
Grateful for the journey so far and eager to drive meaningful change in public health while strengthening collaboration across Latin America and beyond.
Screenshot of a guardian article asking the question quoted in the post
The @theguardian.com is now wondering whether Elon Musk made a "Nazi salute" or a "Roman salute" 🤦♀️
Picking up any secondary school history book would be sufficient to know there is pretty much no difference - Hitler copied Mussolini
This self-guided curriculum from University of Washington SOM provides a structured approach connecting key lung anatomy to patterns of disease & is an effective way to teach chest computed tomography interpretation to pulmonary fellows. www.mededportal.org/doi/10.15766... #MedEd #Medsky
@natmedicine.bsky.social is also now on Bluesky! 🎉
You can follow all of our journals with our starter pack.
How eating fiber->short-chain fatty acid (SCFA) metabolites->anti-cancer effects
nature.com/articles/s42...
nature.com/articles/s42...
"unlike type 1 immune responses, type 2 immunity is perceived as a potential promoter of tumorigenesis. Emerging evidence challenges this perspective, painting a more nuanced picture in which type 2 immunity might protect against or even actively suppress tumour growth and progression." #ImmunoSky
Grateful for the opportunity to briefly discuss the findings in our group’s @jama.com article on identifying asthma endotypes through nasal epithelial transcriptomic profiles with Dr Kristin Walter. @upmc.bsky.social @atscommunity.bsky.social
Fascinating study on pediatric #asthma endotypes (full-text link @jama.com: ja.ma/402KbwE)
#Medsky #Pedsky #PedPulmSky
@ats-peds.bsky.social
In this @jama.com article, Molin Yue+ Dr Kristina Gaietto show similar proportions of nasal epithelial transcriptomic profiles for T2-high, T17-high+ T2-low/T17-low asthma across 3 cohorts of predom. Puerto Rican+ Black youth, with T2-high less common than T2-low profiles. @atscommunity.bsky.social
🧵 Pulse oximeters overestimate arterial oxygen saturation and provide more variable readings in people with darker skin pigmentations.
Despite guidance from the @fda.gov, the reporting of participant skin tones in pulse oximeter testing has been inconsistent.
ja.ma/3DKuKBw
🧪 While LLMs have done well in medical skill comparisons with multiple choice questions, a new study finds GPT-4 scored lower than human doctors in free-text assessments of primary care cases, highlighting its limitations in complex clinical reasoning. 🩺🖥️ #MLSky
Out now in @thetxidjournal.bsky.social!
T-SPOT.TB is more likely to produce actionable results than QFT-TB in patients with cancer being screened for latent TB.
#TxID #IDSky
onlinelibrary.wiley.com/doi/10.1111/...
🧬
A starter pack for PhD students and Postdocs in Immunology to connect 🔽
Drop a 🧬 and I'll add you to the list.
Let's build the upcoming immuno community!
#ImmunoSky 🧪
go.bsky.app/RABVXY4
