The deadline for this PhD is fast approaching. We are looking for a promising synthetic chemist to make new chemical biology tools to learn more about nucleic acid interactions. This is a collaborative project with the Trowbridge Lab in @uomscieng.bsky.social. If interested, get in touch soon!
Really humbled to have been selected by @iuis-online.bsky.social for their rising stars initiative and to be given the opportunity to present at their Congress in Austria this year! 🥳🥳🥳 #immunosky 🧪
Our latest research is now available as a pre-print at BioRxiv. We show that the immune checkpoint receptor TIGIT cannot signal in T cells without simultaneous TCR stimulation.
#ImmunoSky
www.biorxiv.org/content/10.1...
PD1 & Lag3 regulate TCR signal duration in tolerant CD4 T cells
•PD-1 & Lag3 exhibit layered control of CD4 T cell activation
•Co-blockade enhances NFAT-dependent TCR transcription
•NFAT inhibition reverses functional effects of anti-PD-1&Lag3
doi.org/10.1093/immadv/ltaf015
@imtadvances.bsky.social
Now published @cp-iscience.bsky.social
Work lead by David Lecky & Lozan Sheriff in collaboration with @therad-lab.bsky.social and @cameron-wraith.bsky.social showing how IFNg augments T Cell receptor signal strength to enhance type 1 Regulatory T (Tr1) cell development
www.cell.com/iscience/ful...
Our lab has a postdoc position available to use super-resolution microscopy to understand how nanoscopic localisation of immune checkpoints dictates their function.
Please get in touch if interested in applying.
www.jobs.manchester.ac.uk/Job/JobDetai...
#ImmunoSky #Imaging #Microscopy
New postdoc position in @frances-turrell.bsky.social lab. Great opportunity to join a new group, doing exciting work 🧪
Get in touch if you want to chat about life in the lab (it's fab)!
www.jobs.manchester.ac.uk/Job/JobDetai...
#ImmunoSky
Super privileged to be working on such an interesting and important project!
Working out how tumour cell dormancy is regulated is critical to managing reawakening and mitigating this risk for patients. Watch this space for some exciting experiments 🧪
#ImmunoSky #CancerResearch
Online now, our latest manuscript reporting findings on the metabolic basis of cytokine-driven CD4+ T cell expansion, assessed in vitro and during T cell proliferation following autologous stem cell transplantation.
www.sciencedirect.com/science/arti...
🚨 The Menon lab is hiring a postdoc!
Interested in mucosal immunology? Come join our team to study lung-infiltrating B cell dynamics in COPD & other chronic lung diseases @ukri.org @lydiabeckeriii.bsky.social
Please help spread the word #ImmunoSky
www.jobs.manchester.ac.uk/Job/JobDetai...
There's still time to apply for this postdoc position in our lab. Ideally suited to someone wanting to develop some independent research, we have lots of new projects to select from! #immunosky 🧪
PD-1 and Lag3 pathways converge to additively regulate TCR signal duration and NFAT-dependent transcriptional activity during early CD4+ T cell re-activation
www.biorxiv.org/content/10.1...
Really enjoyed being back in Birmingham for a day for my graduation ☺️ Feeling very grateful for the people that helped me through my PhD last few years
Hi Laura, please could I join your starter pack?
