Chris Smith

Great time at #I3Scongress in #saintmalo presenting early data from the #iNTS #CHANTS study with Anna Rydlova 🇫🇷

1/12 🎉 We're excited to announce our Genome Medicine paper benchmarking 1000+ metagenomes (DNA) and metatranscriptomes (RNA) from infectious intestinal disease patients against pathogen diagnostics. The full dataset is public to accelerate pathogen discovery & surveillance: doi.org/10.1186/s130...

Establishing the lowest penicillin concentration to prevent pharyngitis due to Streptococcus pyogenes using a human challenge model (CHIPS): a randomised, double-blind, placebo-controlled trial When steady-state penicillin concentrations are greater than 9 ng/mL, few people will develop experimental emm75 S pyogenes pharyngitis. These data will inform efforts to improve long-acting penicilli...

💥 A blinded #StrepA human challenge PK/PD RCT 💥

All-star collaboration between @thekidsau.bsky.social & #MCRI & #UWA.

@hicvac.bsky.social @1daysooner.bsky.social

Thanks @onisillos.bsky.social @lancetmicrobe.bsky.social for support of human challenge research!

www.thelancet.com/journals/lan...