We posted a biorxiv preprint on structural bioinformatics, AlphaFold modeling & machine learning on predicting specificity of E3 ligase ring domains for different E2 enzymes. 1/4
Preprint: www.biorxiv.org/content/10.6...
Models/data (UbiqCore website): dunbrack.fccc.edu/ubiqcore
After a long (but fun!) postdoc journey, I am very excited to share that I will start my own lab in the Ubiquitin Signalling Division at WEHI. We will study how ubiquitin controls mitochondrial health and its role in neurodegenerative disease. Hiring soon!
Join us for the #Ubiquitin & Friends Symposium 2026, April 29-30, in Vienna!
Fantastic guest speakers👇 & many slots for talks from abstracts, flash-talks & posters. Lots of opportunities to network. Register now to save your spot!
➡️ www.protein-degradation.org/symposium/
#ubfriends2026
A big year for the lab!
We hosted Australia’s first ubiquitin summit in Lorne,
Published the structure of PINK1 on a mitochondrial translocase array,
Reported a new PLpro inhibitor for long COVID,
Celebrated 3 PhD and 1 honours completions,
Went on a lab footy trip, 🏈
Won the Eureka prize!! 🏆
‼️Towards the end of #AusUb25, we caught up with Jonathan Pruneda to discuss ubiquitin signalling and its relationship with host-pathogen interactions. It was an amazing conference and such a great chance to meet people from across the ubiquitin field 🤩
‼️ Following on from our “M1 chains everywhere!” session at #AusUb25 we took the chance to interview one of the pioneering researchers in this field, Kazuhiro Iwai. Have a look below! ✨✨✨
‼️Have a listen to a little about Kylie Walter’s exciting new research, conference talk, and her experience at #AusUb2025. What did she enjoy most about the conference?
More interviews to come in the next week so stay tuned 😁
‼️It was wonderful to have Professor Kay Hoffmann at the #AusUb25 - and even better to get the chance to interview him! Hear about his experiences in industry and academia as well as his love for proteins😁
#ArtAdventCalendar Day 5
Ubiquitin - Spraypaint on conrete
ICYMI: New online: UBA6 specificity for ubiquitin E2 conjugating enzymes reveals a priority mechanism of BIRC6
💯
'A scientific figure (or art in general) is more than a function of communication, it’s a reflection of how we interact with, interpret, and perceive science.'
It’s hard to believe that #AusUb2025 has already come to an end 😢. Don’t worry though - we’ll still be posting our speaker interviews in the next couple of days.
Here’s what Sonja Lorenz thought of the Australian Ubiquitin Summit. 👇
A huge shout-out to David Komander, Grant Dewson, Bernhard Lechtenberg, Rebecca Feltham and Aimee for the stellar organisation of #AusUb2025 and for making the first Ub Summit such a success.
Already excited for what comes next 🌊
@ausub.bsky.social
Connecting with so many brilliant #ubiquitin aficionados from around the world was genuinely energising: a reminder of how special this community is😇
Also grateful for the engaging discussions at my poster that led to a Best Poster Award. 🏆
What a fantastic few days at The *inaugural* Australian Ubiquitin Summit 🤩 #UbiquitinByTheBay
It was fun to contribute behind the scenes in the lead-up, help chair the opening session, host lightning talks, and dive into conversations during the poster session and EMCR panel discussions.
Is there any chain more enigmatic than K27-Ub? 😍
#UbiquitinByTheBay
#AusUb2025
Is there any biomolecule thats not #Ubiquitinated ? 🫣
It was super fun to chair my fav session on 'Ubiquitinating EVERYthing' during the kickstart event of #AusUb2025
Have you already spotted some ‘local residents’ at Lorne? Share photos and tag #AusUb2025!
We were also honoured to have Ebony Hickey welcoming everyone to Gadubanud country with a powerful story. Indigenous Australians have a long and continuing history, and were the first scientists on this land.
Today is the day! The Inaugural Australian Ubiquitin Summit #AusUb2025 was officially opened by committee chair David Komander.
⏰#AusUb2025 is TOMORROW!!! Here’s our final pre-conference interview - have a listen to Bernhard Lechtenberg’s thoughts on conference organising and what he’s most looking forward to!
@lechtenberglab.bsky.social
Any fun conference moments to share? Impressed by any of our speakers? Got any cute wildlife pics 🦜? Share your #AusUb2025 moments using the hashtag!
Don’t forget to follow us on socials by scanning the QR codes ✨✨
We can’t wait to see you in Lorne tomorrow 😉
Can't wait for #AusUb2025 to start tomorrow ⏰ ? Head over for a sneak peak 👀 on what's coming! 👇
lorneubiquitin.org/program-2025
Watch this interview with our organising committee’s resident PROTAC expert Rebecca (Bekky) Feltham to learn about what went into organising the Targeted Protein Degradation (TPD) Day and more about the conference! 📝
⏳Three days to go until #AusUb2025! What is Grant Dewson most looking forward to in the upcoming Ubiquitin Summit? 🤔 Perhaps the speakers? Perhaps the free coffee ☕️? Or perhaps the very British prospect of cloudy, sunless days at the beach☁️? Watch the video to find out!
⏳Four days to go until #AusUb2025! Check out the video below to hear some conference tips and tricks from our committee chair David Komander (and some potentially controversial interest rankings!?!?).
More interviews to come in the next few days so watch this space 😉
Stay tuned for some ✨exclusive✨ interviews from our organising committee members (including committee chair David Komander!).
A poster advertising the Australian Ubiquitin Summit in Lorne from the 20th - 23rd of November. The logo of the conference, as well as a note that there is a Targeted Protein Degradation Day are displayed at the top of the poster. The rest of the poster contains a photo of the bay at Lorne, looking out from rock pools into the ocean. Sitting atop this image is a list of the invited speakers (available on the Lorne Ubiquitin website), and below a note that the meeting is being organised in conjunction with the International Symposium on Autophagy, held on the 16th - 20th of November.
📢 All ubiquitin aficionados! 📢
We are gearing up for the first Australian Ubiquitin Summit in three weeks 🤩🗓️
Are you ready for talking ubiquitin by the bay?
🗓️ 20-23 Nov
📍Mantra, Lorne, VIC
Chaired by David Komander (@komanderlab.bsky.social)
#AusUb2025
#ResearchExplained!
Using BEST-HSQC NMR, Dr Rashmi Agrata from Dr Ranabir Das's team at NCBS team tracked ubiquitin deamidation in real-time, revealing varied deamidase efficiencies despite similar structures.
Read here: bit.ly/3L56RIR
✏️Christeen Paulson
