In this modeling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries 🧪 #MedSky #TB
plos.io/4ryyBFX
I wanted dinner recommendations so I scraped 13,000+ London restaurants and accidentally discovered Google Maps is running a shadow economy. Anyway here's a dashboard and a political economy thesis: open.substack.com/pub/laurenle...
Our photos are telling a story are at a display at the #2025UnionConference #CommunityConnect, Bella Centre Balcony 3.
📷 Our photography exhibition features work that we have conducted using the photovoice study method.
Learn more: light.lstmed.ac.uk/research-2
TODAY!
Innovation from Nigeria at the Union Conference! #WCLH2025
Nathan Zoakah presents an e-poster on how community-based initiatives improved TB knowledge and attitudes in Nasarawa — using machine learning to assess impact.
#TB #PublicHealth #GlobalHealth #Nigeria @zanklic.bsky.social
Is TB more common in cities or rural areas?
New analysis presented by Seyed Alireza Mortazavi at #WCLH2025 today!
• Urban > Rural in Africa
• Rural > Urban in Western Pacific
• Similar elsewhere
2.3 million participants 26 countries using a Bayesian model fitted to WHO data.
🤝 by @LIGHTonTB
All are welcome to join the Gender Equity in TB Working Group today at 12:30 in Room B4B @theunion.org! We'll share updates on working group activities and host a panel discussion on progress to date and ways forward to ensure an equitable and inclusive #TB response.
💬 Can community-wide TB screening help bend the curve in Uganda?
Today at #WCLH2025, @alexandra-richards.bsky.social presents modelling on Uganda’s twice-yearly active case-finding campaigns.
The work suggests these community efforts are meaningfully reducing #TB incidence and mortality.
At the World Conference on Lung Health in Copenhagen, @johngreensbluesky.bsky.social apologized on behalf of his country (USA) for the aid cuts that are devastating
“On behalf of my country, I am sorry and also that I am ashamed. It seems small minded but that’s because it is small minded”
Day 1: the LIGHT Annual Consortium meeting kicks off this morning at the Crown Plaza in Copenhagen.
Consortium partners from Nigeria, Malawi, Kenya, Uganda and the UK meet to discuss the key research findings, research uptake and impact so far.
Sobering study on the devastating impact of aid cuts on tuberculosis incidence and mortality in low and middle income countries
Governments of highest TB burden nations will need to wake up and invest more!
www.thelancet.com/journals/lan...
Reduced international donor funding through not only the termination of #USAID, but also announced reductions in donor pledges to #TheGlobalFund from other countries, could lead to substantial potential impacts on #TB morbidity and mortality.
Read how in our new study in @lancetgh.bsky.social 👇
Our work estimating the potential impacts of reductions in international donor funding for #TB is now out in @lancetgh.bsky.social:
bit.ly/3TDl28T
@raclark18.bsky.social @cfmcquaid.bsky.social @alexandra-richards.bsky.social @top-j.bsky.social @reinhouben.bsky.social @richardwhite321.bsky.social
The first page of the Lancet Public Health manuscripts
Two graphs showing a) prevalence of MTB immunoreactivity by sex and age and b) ARTI by sex and age
Figure showing male-to-female prevalence ratio in MTB immunoreactivity
In meta analysis of data from nearly half a million people, we found that men have higher M. #tuberculosis immunoreactivity risk than women.
Likely to be key driver of
sex differences in global tuberculosis morbidity & mortality
@hannahrickman.bsky.social 🛟🧪
authors.elsevier.com/sd/article/S...
Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.
World report on social determinants of health equity by the @who.int
"Conclusion: Equity is a political choice"
⬇️
This is a timely impressive report in both its breadth & depth 👏
iris.who.int/bitstream/ha...
#Tuberculosis prevention and care relies heavily on international donor funding in many settings. In our latest preprint, we examine the potential impact of reductions in international donor funding for #TB - by the US and by other major donor countries. 1/8
www.medrxiv.org/content/10.1...
Climate-driven migration and displacement and their potential impact on TB in Latin America gh.bmj.com/content/10/4... @cfmcquaid.bsky.social @reinhouben.bsky.social @lshtm-tbmod.bsky.social
Line chart showing median number of TB deaths in 79 low- and middle-income countries from 2010 through 2040. A black line shows a decline from 1.25 million deaths in 2010 to just under 1 million deaths in 2024. A blue line shows the number of deaths staying constant through 2040 if 2024 funding and programmes are maintained. A red line shows the number of deaths increasing to 1.2 million in 2040 if US funding to national TB programmes is terminated.
New pre-print modelling impact of US funding cuts on HIV, #TB, MCH and family planning. We estimate impact of termination of US funding to NTPs via #USAID & The Global Fund may lead to 2.2 (1.5-2.9) million excess TB deaths between 2025 and 2040, reversing over a decade of progress.
bit.ly/4lowp18
Our latest pre-print led by @alexandra-richards.bsky.social shows that improving #TB treatment coverage among men to the level achieved among women could reduce morbidity and mortality in men, women, and children. Further evidence of the need for gender-responsive TB prevention and care!
Great to be able to finally get this work out, closing out my time with @lshtm-tbmod.bsky.social
As I've adjusted the code to using ggplot and added some extra features, here is the link to my GitHub with the code and some (hopefully) simple instructions.
github.com/alexandrasri...
If anyone gives this a go, I'd love to see other examples!
A year ago, I was tasked with creating a timeline for @lshtm-tbmod.bsky.social and we came across this amazing example of a way to keep track of a group with a long history.
We now have a record of our history going back to 2011, and I hope that this can stay alive and continuously updated as well!
Trump Is Ceding Ground to a Deadly Enemy, an essay by me adapted from my book Everything Is Tuberculosis.
www.theatlantic.com/health/archi...
PhD position (London, UK)
Quantify the effects of climate change on TB
with @cfmcquaid.bsky.social @reinhouben.bsky.social @laragosce.bsky.social
at @cmmid-lshtm.bsky.social @tb-lshtm.bsky.social @lshtm.bsky.social
More details: http://iddjobs.org/jobs/2253
Hot off the press! 🔥 Our new systematic review digs deep into #TB cluster randomised trials, exploring how contamination can influence results, and offers insights for improving trial design #TBSky #IDSky #MedSky doi-org.ez.lshtm.ac.uk/10.5588/ijtl...
The advert is now live here:
jobs.lshtm.ac.uk/EPH-EPED-202...
Until August 2027 we would be working on data analysis and modelling to try and untangle the dynamics of #AMR by age and sex exploring electronic health records 🧫📑👩💻. Get in touch if any questions!
I’m hiring! watch this space for a 2yr position on modelling and data analysis to determine how #AMR varies by age and sex @lshtm.bsky.social
Reducing #TB burden requires understanding local contexts. Our new preprint emphasizes the importance of considering social contact patterns for interventions like active case finding, infection prevention & control, & cluster trial design #TBsky #IDsky #GlobalHealth
www.medrxiv.org/content/10.1...
New preprint (with all pre-print caveats!) tinyurl.com/589ffhu4 on Mtb infection risk by sex & age.
Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky
Our ASCENT modelling paper on Digital Adherence Technologies (DAT) for TB treatment is now out in BMJ Global Health gh.bmj.com/content/9/12... DATs may have limited epidemiological impact but can reduce costs and have important budgetary implications. @cfmcquaid.bsky.social @lshtm-tbmod.bsky.social
